{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=22q11.2+Syndrome",
    "query": {
      "condition": "22q11.2 Syndrome"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T03:06:15.075Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00105274",
      "title": "Velocardiofacial (VCFS; 22q11.2; DiGeorge) Syndrome Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "DiGeorge Syndrome",
        "Velocardiofacial Syndrome",
        "22q11.2 Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": null,
      "start_date": "2005-03-07",
      "completion_date": "2010-02-02",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-05-22T03:06:15.075Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00105274"
    },
    {
      "nct_id": "NCT00916955",
      "title": "Genetic Modifiers for 22q11.2 Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "22q11.2 Deletion Syndrome"
      ],
      "interventions": [
        {
          "name": "Observation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "State University of New York - Upstate Medical University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": null,
      "start_date": "2008-03",
      "completion_date": "2015-02",
      "has_results": false,
      "last_update_posted_date": "2021-10-20",
      "last_synced_at": "2026-05-22T03:06:15.075Z",
      "location_count": 1,
      "location_summary": "Syracuse, New York",
      "locations": [
        {
          "city": "Syracuse",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00916955"
    },
    {
      "nct_id": "NCT05290493",
      "title": "NB-001 in Children and Adolescents With 22q11 Deletion Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "22q11 Deletion Syndrome"
      ],
      "interventions": [
        {
          "name": "NB-001",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Nobias Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Years to 17 Years"
      },
      "enrollment_count": 37,
      "start_date": "2022-02-10",
      "completion_date": "2023-06-09",
      "has_results": true,
      "last_update_posted_date": "2025-02-10",
      "last_synced_at": "2026-05-22T03:06:15.075Z",
      "location_count": 3,
      "location_summary": "Aurora, Colorado • Philadelphia, Pennsylvania • Seattle, Washington",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05290493"
    },
    {
      "nct_id": "NCT00161109",
      "title": "Genetics and Psychopathology in the 22q11 Deletion Syndrome",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chromosome 22q11.2 Deletion Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "UMC Utrecht",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "8 Years to 20 Years"
      },
      "enrollment_count": 175,
      "start_date": "2002-10",
      "completion_date": "2012-10",
      "has_results": false,
      "last_update_posted_date": "2006-10-13",
      "last_synced_at": "2026-05-22T03:06:15.075Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00161109"
    },
    {
      "nct_id": "NCT01781923",
      "title": "Cognitive Remediation in 22q11DS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "22q11.2 Deletion Syndrome",
        "Velo-Cardio-Facial Syndrome"
      ],
      "interventions": [
        {
          "name": "Cognitive remediation program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Small group social skills training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "11 Years to 17 Years"
      },
      "enrollment_count": 38,
      "start_date": "2010-10",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2015-08-10",
      "last_synced_at": "2026-05-22T03:06:15.075Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01781923"
    },
    {
      "nct_id": "NCT05149898",
      "title": "Open-Label Study of ZYN002 Administered as a Transdermal Gel to Children and Adolescents With 22q11.2 Deletion Syndrome (INSPIRE)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "22Q11.2 Deletion Syndrome"
      ],
      "interventions": [
        {
          "name": "ZYN002",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Harmony Biosciences Management, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "4 Years to 17 Years"
      },
      "enrollment_count": 20,
      "start_date": "2020-02-19",
      "completion_date": "2022-11-09",
      "has_results": true,
      "last_update_posted_date": "2026-03-09",
      "last_synced_at": "2026-05-22T03:06:15.075Z",
      "location_count": 1,
      "location_summary": "Greenville, South Carolina",
      "locations": [
        {
          "city": "Greenville",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05149898"
    },
    {
      "nct_id": "NCT03836300",
      "title": "Parent and Infant Inter(X)Action Intervention (PIXI)",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fragile X Syndrome",
        "Angelman Syndrome",
        "Prader-Willi Syndrome",
        "Dup15Q Syndrome",
        "Duchenne Muscular Dystrophy",
        "Phelan-McDermid Syndrome",
        "Rett Syndrome",
        "Smith Magenis Syndrome",
        "Williams Syndrome",
        "Turner Syndrome",
        "Klinefelter Syndrome",
        "Chromosome 22q11.2 Deletion Syndrome",
        "Tuberous Sclerosis",
        "Down Syndrome"
      ],
      "interventions": [
        {
          "name": "Parent-Infant Inter(X)action Intervention (PIXI)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "RTI International",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "Up to 99 Years"
      },
      "enrollment_count": 120,
      "start_date": "2018-11-30",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-31",
      "last_synced_at": "2026-05-22T03:06:15.075Z",
      "location_count": 1,
      "location_summary": "Research Triangle Park, North Carolina",
      "locations": [
        {
          "city": "Research Triangle Park",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03836300"
    },
    {
      "nct_id": "NCT07493096",
      "title": "Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neurodevelopmental Disorders",
        "Neurodevelopmental Disorders (NDD)",
        "Neurodevelopmental Disorders and Developmental Abnormalities",
        "Developmental Delay (Disorder)",
        "Cerebral Palsy (CP)",
        "Cerebral Palsy Hemiparetic Cerebral Palsy Spasticity Gait Disorders, Neurologic Postural Balance Impairment",
        "Cerebral Palsy Infantile",
        "Cerebral Palsy Spastic Hemiplegic",
        "Cerebral Palsy, Dyskinetic",
        "Autism Spectrum Disorder",
        "Autism Spectrum Disorder (ASD",
        "Hypoxic Ischemic Encephalopathy",
        "Hypoxic Ischemic Encephalopathy (HIE)",
        "Traumatic Brain Injury (TBI)",
        "Sensory Processing Disorder",
        "Chromosomal Abnormalities",
        "Genetic Disorders",
        "Down Syndrome (Trisomy 21)",
        "Fragile X Syndrome (FXS)",
        "RETT Syndrome With Proven MECP2 Mutation",
        "Williams Syndrome",
        "22q11.2 Deletion Syndrome",
        "Sensorimotor Integration"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Healing Hope International",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "4 Years to 12 Years"
      },
      "enrollment_count": 100,
      "start_date": "2026-03-01",
      "completion_date": "2036-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-25",
      "last_synced_at": "2026-05-22T03:06:15.075Z",
      "location_count": 1,
      "location_summary": "The Woodlands, Texas",
      "locations": [
        {
          "city": "The Woodlands",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07493096"
    },
    {
      "nct_id": "NCT00556530",
      "title": "Examining Genetic Factors That Affect the Severity of 22q11.2 Deletion Syndrome",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "DiGeorge Syndrome",
        "22q11.2 Deletion Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Albert Einstein College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1000,
      "start_date": "2016-07",
      "completion_date": "2029-06",
      "has_results": false,
      "last_update_posted_date": "2025-07-22",
      "last_synced_at": "2026-05-22T03:06:15.075Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00556530"
    },
    {
      "nct_id": "NCT02895906",
      "title": "Safety and Efficacy Study of NFC-1 in Subjects Aged 12-17 Years With 22q11.2DS & Associated Neuropsychiatric Conditions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "22q11.2 Deletion Syndrome"
      ],
      "interventions": [
        {
          "name": "NFC-1",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Aevi Genomic Medicine, LLC, a Cerecor company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "12 Years to 17 Years"
      },
      "enrollment_count": 2,
      "start_date": "2016-11-28",
      "completion_date": "2017-04-20",
      "has_results": false,
      "last_update_posted_date": "2022-03-25",
      "last_synced_at": "2026-05-22T03:06:15.075Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02895906"
    }
  ]
}