{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=ACL&page=2",
    "query": {
      "condition": "ACL",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=ACL&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:26:21.822Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00625885",
      "title": "Multicenter ACL Revision Study (MARS)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Rupture of Anterior Cruciate Ligament"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "12 Years to 65 Years"
      },
      "enrollment_count": 1234,
      "start_date": "2006-03-26",
      "completion_date": "2029-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-06-17",
      "last_synced_at": "2026-05-22T05:26:21.822Z",
      "location_count": 47,
      "location_summary": "La Jolla, California • Los Angeles, California • San Francisco, California + 39 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Aspen",
          "state": "Colorado"
        },
        {
          "city": "Boulder",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00625885"
    },
    {
      "nct_id": "NCT05461326",
      "title": "Quadriceps Tendon Versus Bone Patellar Tendon Bone Autograft ACL Reconstruction RCT",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Orthopedic Disorder",
        "Anterior Cruciate Ligament Injuries"
      ],
      "interventions": [
        {
          "name": "Quad tendon",
          "type": "PROCEDURE"
        },
        {
          "name": "BTB",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "14 Years to 65 Years"
      },
      "enrollment_count": 100,
      "start_date": "2023-09-26",
      "completion_date": "2030-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-06-08",
      "last_synced_at": "2026-05-22T05:26:21.822Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05461326"
    },
    {
      "nct_id": "NCT02602561",
      "title": "Effects of HMB Supplementation on Recovery Following ACL Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL Injury"
      ],
      "interventions": [
        {
          "name": "HMB",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Metabolic Technologies Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "18 Years to 49 Years"
      },
      "enrollment_count": 4,
      "start_date": "2015-11",
      "completion_date": "2017-08",
      "has_results": false,
      "last_update_posted_date": "2019-03-13",
      "last_synced_at": "2026-05-22T05:26:21.822Z",
      "location_count": 1,
      "location_summary": "Ames, Iowa",
      "locations": [
        {
          "city": "Ames",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02602561"
    },
    {
      "nct_id": "NCT03519555",
      "title": "BIOSURE™ RG Knee Safety & Performance Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "ACL Repair",
        "Posterior Cruciate Ligament (PCL) Repair",
        "Medial Collateral Ligament (MCL)",
        "Lateral Collateral Ligament (LCL)",
        "Posterior Oblique Ligament (POL)",
        "Patellar Realignment and Tendon Repairs",
        "Vastus Medialis Obliquus Advancement",
        "Iliotibial Band Tenodesis",
        "Extra-capsular Repairs",
        "Knee Repair"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Smith & Nephew, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2017-11-09",
      "completion_date": "2020-10-05",
      "has_results": false,
      "last_update_posted_date": "2021-07-08",
      "last_synced_at": "2026-05-22T05:26:21.822Z",
      "location_count": 3,
      "location_summary": "Rockford, Illinois • Charlotte, North Carolina • Houston, Texas",
      "locations": [
        {
          "city": "Rockford",
          "state": "Illinois"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03519555"
    },
    {
      "nct_id": "NCT04682392",
      "title": "ACL Bone Health and Loading Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL Tear"
      ],
      "interventions": [
        {
          "name": "Delfi's PTS Personalized Tourniquet System for Blood Flow Restriction Group",
          "type": "DEVICE"
        },
        {
          "name": "Standard ACL rehab",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Candice Dunkin, MS, LAT, ATC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "22 Years",
        "sex": "ALL",
        "summary": "16 Years to 22 Years"
      },
      "enrollment_count": 19,
      "start_date": "2021-02-17",
      "completion_date": "2025-05-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-05-22T05:26:21.822Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04682392"
    },
    {
      "nct_id": "NCT03389685",
      "title": "Can PRP Reduce Pro-Inflammatory Biomarkers Following ACL Injury",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "ACL - Anterior Cruciate Ligament Rupture",
        "ACL Injury"
      ],
      "interventions": [
        {
          "name": "Platelet Rich Plasma",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Saline Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 0,
      "start_date": "2018-09-09",
      "completion_date": "2024-02",
      "has_results": false,
      "last_update_posted_date": "2024-04-15",
      "last_synced_at": "2026-05-22T05:26:21.822Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03389685"
    },
    {
      "nct_id": "NCT07046000",
      "title": "MRI Evaluation of Graft Maturation Following ACL Reconstruction",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "ACL Tears"
      ],
      "interventions": [
        {
          "name": "MRI",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Skye Biologics Holdings, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "14 Years to 50 Years"
      },
      "enrollment_count": 10,
      "start_date": "2026-08-01",
      "completion_date": "2028-02",
      "has_results": false,
      "last_update_posted_date": "2026-04-24",
      "last_synced_at": "2026-05-22T05:26:21.822Z",
      "location_count": 1,
      "location_summary": "Sugar Land, Texas",
      "locations": [
        {
          "city": "Sugar Land",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07046000"
    },
    {
      "nct_id": "NCT01756560",
      "title": "Effect of Dexamethasone on Duration of Lower Extremity Blocks With Bupivacaine in Subjects Having ACL Repair",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Duration of Pain Relief"
      ],
      "interventions": [
        {
          "name": "dexamethsone",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 2,
      "start_date": "2013-01",
      "completion_date": "2015-01",
      "has_results": true,
      "last_update_posted_date": "2019-05-14",
      "last_synced_at": "2026-05-22T05:26:21.822Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01756560"
    },
    {
      "nct_id": "NCT04593264",
      "title": "Quantifying the Benefits of Supervised vs. Unsupervised Pre-habilitation for Patients With Acute ACL Tears",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Rupture",
        "Anterior Cruciate Ligament Tear",
        "Anterior Cruciate Ligament Injuries"
      ],
      "interventions": [
        {
          "name": "Self-guided pre-habilitation exercise program",
          "type": "OTHER"
        },
        {
          "name": "Traditional pre-habilitation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "WellSpan Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "13 Years to 50 Years"
      },
      "enrollment_count": 128,
      "start_date": "2021-02-23",
      "completion_date": "2022-06-30",
      "has_results": false,
      "last_update_posted_date": "2023-03-27",
      "last_synced_at": "2026-05-22T05:26:21.822Z",
      "location_count": 1,
      "location_summary": "York, Pennsylvania",
      "locations": [
        {
          "city": "York",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04593264"
    },
    {
      "nct_id": "NCT05190120",
      "title": "Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Tear",
        "Knee Meniscus Tear"
      ],
      "interventions": [
        {
          "name": "Femoral Nerve Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Adductor Canal Nerve Block",
          "type": "PROCEDURE"
        },
        {
          "name": "preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine",
          "type": "DRUG"
        },
        {
          "name": "Preoperative Adductor canal block with 0.75%% ropivacaine 13.3ml.",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 132,
      "start_date": "2016-01",
      "completion_date": "2022-03-20",
      "has_results": true,
      "last_update_posted_date": "2025-09-30",
      "last_synced_at": "2026-05-22T05:26:21.822Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05190120"
    }
  ]
}