{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=ALI",
    "query": {
      "condition": "ALI"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 50,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=ALI&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T12:43:11.459Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04144959",
      "title": "A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo Aspiration System",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lower Extremity Acute Limb Ischemia",
        "LE ALI"
      ],
      "interventions": [
        {
          "name": "Indigo Aspiration System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Penumbra Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 119,
      "start_date": "2019-12-17",
      "completion_date": "2023-10-20",
      "has_results": true,
      "last_update_posted_date": "2025-06-27",
      "last_synced_at": "2026-07-22T12:43:11.459Z",
      "location_count": 14,
      "location_summary": "Stanford, California • Danbury, Connecticut • Bradenton, Florida + 11 more",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Danbury",
          "state": "Connecticut"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04144959"
    },
    {
      "nct_id": "NCT00429637",
      "title": "Continuous Exhaled Breath Condensate pH in Mechanically Ventilated Patients",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Respiratory Distress Syndrome, Adult",
        "Respiratory Syncytial Virus Infections",
        "Pneumonia",
        "Acute Lung Injury"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Hour",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "1 Hour and older"
      },
      "enrollment_count": 120,
      "start_date": "2004-12",
      "completion_date": "2009-01",
      "has_results": false,
      "last_update_posted_date": "2008-08-07",
      "last_synced_at": "2026-07-22T12:43:11.459Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00429637"
    },
    {
      "nct_id": "NCT02184208",
      "title": "Retrospective Review of Mechanically Ventilated Patients Using a Continuous Data Collection System.",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mechanical Ventilation",
        "Acute Respiratory Distress Syndrome",
        "Hypoxic Respiratory Failure"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "1 Day to 35 Years"
      },
      "enrollment_count": 278,
      "start_date": "2014-01-17",
      "completion_date": "2017-01-09",
      "has_results": true,
      "last_update_posted_date": "2018-02-05",
      "last_synced_at": "2026-07-22T12:43:11.459Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02184208"
    },
    {
      "nct_id": "NCT04344184",
      "title": "SAFEty Study of Early Infusion of Vitamin C for Treatment of Novel Coronavirus Acute Lung Injury (SAFE EVICT CORONA-ALI)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "COVID-19",
        "Lung Injury, Acute",
        "Kidney Injury"
      ],
      "interventions": [
        {
          "name": "L-ascorbic acid",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 47,
      "start_date": "2020-12-18",
      "completion_date": "2022-06-10",
      "has_results": true,
      "last_update_posted_date": "2024-04-04",
      "last_synced_at": "2026-07-22T12:43:11.459Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04344184"
    },
    {
      "nct_id": "NCT00883948",
      "title": "Early Versus Delayed Enteral Feeding to Treat People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Respiratory Distress Syndrome, Adult"
      ],
      "interventions": [
        {
          "name": "Minimal (Trophic) Feeding",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Full Feeding",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "13 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2007-12",
      "completion_date": "2011-05",
      "has_results": false,
      "last_update_posted_date": "2016-04-13",
      "last_synced_at": "2026-07-22T12:43:11.459Z",
      "location_count": 39,
      "location_summary": "Fresno, California • Sacramento, California • San Francisco, California + 19 more",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00883948"
    },
    {
      "nct_id": "NCT01083355",
      "title": "Assessing Respiratory Variability During Mechanical Ventilation in Acute Lung Injury (ALI)",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Lung Injury",
        "Adult Respiratory Distress Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Boston Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2010-03",
      "completion_date": "2016-03",
      "has_results": false,
      "last_update_posted_date": "2016-03-30",
      "last_synced_at": "2026-07-22T12:43:11.459Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01083355"
    },
    {
      "nct_id": "NCT00217321",
      "title": "Parkinson's Disease Registry of the Muhammad Ali Parkinson Center",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Parkinson's Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Muhammad Ali Parkinson Research Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 20000,
      "start_date": "2003-11",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2010-07-21",
      "last_synced_at": "2026-07-22T12:43:11.459Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00217321"
    },
    {
      "nct_id": "NCT00980915",
      "title": "Timing and Intensity of the Exposures and Attributable Burden of Acute Lung Injury",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Lung Injury",
        "Acute Respiratory Distress Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6600,
      "start_date": "2008-12",
      "completion_date": "2020-12",
      "has_results": false,
      "last_update_posted_date": "2021-02-05",
      "last_synced_at": "2026-07-22T12:43:11.459Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00980915"
    },
    {
      "nct_id": "NCT03021824",
      "title": "Severe ARDS: Generating Evidence",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Respiratory Distress Syndrome",
        "Acute Respiratory Failure With Hypoxia",
        "Acute Respiratory Failure"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2400,
      "start_date": "2016-10-01",
      "completion_date": "2017-04-30",
      "has_results": false,
      "last_update_posted_date": "2020-01-28",
      "last_synced_at": "2026-07-22T12:43:11.459Z",
      "location_count": 28,
      "location_summary": "Tucson, Arizona • Los Angeles, California • Jacksonville, Florida + 22 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03021824"
    },
    {
      "nct_id": "NCT01274481",
      "title": "Iloprost Effects on Gas Exchange and Pulmonary Mechanics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Acute Respiratory Distress Syndrome",
        "Acute Lung Injury",
        "Pulmonary Hypertension"
      ],
      "interventions": [
        {
          "name": "Iloprost",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2011-03",
      "completion_date": "2012-07",
      "has_results": false,
      "last_update_posted_date": "2012-08-10",
      "last_synced_at": "2026-07-22T12:43:11.459Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01274481"
    }
  ]
}