{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=ALS&page=41", "query": { "condition": "ALS", "page": 41 }, "page_size": 10 }, "pagination": { "page": 41, "page_size": 10, "total_count": 487, "total_pages": 49, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=ALS&page=42&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=ALS&page=40&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-22T23:53:50.225Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00230074", "title": "A Long-term Extension Study of TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis(ALS)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Amyotrophic Lateral Sclerosis" ], "interventions": [ { "name": "TCH346", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "21 Years to 80 Years" }, "enrollment_count": 350, "start_date": "2004-11", "completion_date": "2005-02", "has_results": false, "last_update_posted_date": "2011-11-23", "last_synced_at": "2026-10-22T23:53:50.225Z", "location_count": 1, "location_summary": "East Hanover, New Jersey", "locations": [ { "city": "East Hanover", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT00230074" }, { "nct_id": "NCT01495390", "title": "A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Amyotrophic Lateral Sclerosis", "Nervous System Diseases", "Sclerosis", "Motor Neuron Disease", "Spinal Cord Diseases", "Central Nervous System Diseases", "Neurodegenerative Diseases", "Neuromuscular Diseases", "ALS" ], "interventions": [], "intervention_types": [], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 139, "start_date": "2011-11", "completion_date": "2016-12-31", "has_results": false, "last_update_posted_date": "2017-05-30", "last_synced_at": "2026-10-22T23:53:50.225Z", "location_count": 6, "location_summary": "Phoenix, Arizona • Jacksonville, Florida • Atlanta, Georgia + 3 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Worcester", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01495390" }, { "nct_id": "NCT04220190", "title": "RAPA-501 Therapy for ALS", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Amyotrophic Lateral Sclerosis" ], "interventions": [ { "name": "RAPA-501 Autologous T stem cells", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Rapa Therapeutics LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 41, "start_date": "2025-01-02", "completion_date": "2028-07-01", "has_results": false, "last_update_posted_date": "2026-09-29", "last_synced_at": "2026-10-22T23:53:50.225Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04220190" }, { "nct_id": "NCT03016897", "title": "ALS Testing Through Home-based Outcome Measures", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Amyotrophic Lateral Sclerosis" ], "interventions": [ { "name": "Respirometer, Handgrip Meter, Skulpt Chisel, ActigraphyMeter", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Jeremy Shefner", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 144, "start_date": "2017-02-22", "completion_date": "2019-09-30", "has_results": false, "last_update_posted_date": "2023-02-08", "last_synced_at": "2026-10-22T23:53:50.225Z", "location_count": 1, "location_summary": "Phoenix, Arizona", "locations": [ { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT03016897" }, { "nct_id": "NCT07142291", "title": "PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALS", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Amyotrophic Lateral Sclerosis (ALS)" ], "interventions": [ { "name": "Cromolyn Sodium (34.2 mg BID)", "type": "DRUG" }, { "name": "Cromolyn Sodium (17.1 mg BID)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Riluzole (100 mg)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "PhenoNet, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 105, "start_date": "2025-11-25", "completion_date": "2027-06", "has_results": false, "last_update_posted_date": "2026-07-23", "last_synced_at": "2026-10-22T23:53:50.225Z", "location_count": 5, "location_summary": "Scottsdale, Arizona • La Jolla, California • San Francisco, California + 2 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "La Jolla", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT07142291" }, { "nct_id": "NCT02493491", "title": "Neurogenic Dysphonia/Dysphagia Registry", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Neurogenic Dysphonia", "Neurogenic Dysphagia" ], "interventions": [], "intervention_types": [], "sponsor": "Merz North America, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 146, "start_date": "2015-06", "completion_date": "2016-09", "has_results": false, "last_update_posted_date": "2016-09-09", "last_synced_at": "2026-10-22T23:53:50.225Z", "location_count": 12, "location_summary": "La Jolla, California • Sacramento, California • Augusta, Georgia + 8 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Augusta", "state": "Georgia" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Burlington", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02493491" }, { "nct_id": "NCT03516994", "title": "Reducing Disparities in the Quality of Advance Care Planning for Older Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Metastatic Cancer", "Congestive Heart Failure", "Chronic Obstructive Pulmonary Disease", "Parkinson Disease", "Interstitial Lung Disease", "Amyotrophic Lateral Sclerosis", "End Stage Liver Disease", "End Stage Renal Disease", "Diabetes Complications" ], "interventions": [ { "name": "Respecting Choices First Steps", "type": "BEHAVIORAL" }, { "name": "Five Wishes Form", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "65 Years", "maximum_age": null, "sex": "ALL", "summary": "65 Years and older" }, "enrollment_count": 790, "start_date": "2018-08-01", "completion_date": "2024-04-15", "has_results": false, "last_update_posted_date": "2024-05-16", "last_synced_at": "2026-10-22T23:53:50.225Z", "location_count": 4, "location_summary": "Birmingham, Alabama • Atlanta, Georgia • Columbia, South Carolina + 1 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Columbia", "state": "South Carolina" }, { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03516994" }, { "nct_id": "NCT05635266", "title": "Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Age-Related Macular Degeneration", "Allergies", "Alpha-Gal Syndrome", "Alzheimer Disease", "Amyloidosis", "Ankylosing Spondylitis", "Arthritis", "Alopecia Areata", "Asthma", "Atopic Dermatitis", "Autism", "Autoimmune Hepatitis", "Behcet's Disease", "Beta-Thalassemia", "Cancer", "Celiac Disease", "Kidney Diseases", "COPD", "Crohn Disease", "Cystic Fibrosis", "Diabetes", "Dravet Syndrome", "DMD", "Fibromyalgia", "Graves Disease", "Thyroid Diseases", "Hepatitis", "Hidradenitis Suppurativa", "ITP", "Leukemia", "ALS", "Lupus or SLE", "Lymphoma", "Multiple Sclerosis", "Myasthenia Gravis", "Heart Diseases", "Parkinson Disease", "Pemphigus Vulgaris", "Cirrhosis", "Psoriasis", "Schizophrenia", "Scleroderma", "Sickle Cell Disease", "Stroke", "Ulcerative Colitis", "Vasculitis", "Vitiligo" ], "interventions": [ { "name": "Specimen sample", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Sanguine Biosciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 20000, "start_date": "2021-10-26", "completion_date": "2025-10", "has_results": false, "last_update_posted_date": "2024-05-07", "last_synced_at": "2026-10-22T23:53:50.225Z", "location_count": 1, "location_summary": "Waltham, Massachusetts", "locations": [ { "city": "Waltham", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05635266" }, { "nct_id": "NCT04414345", "title": "HEALEY ALS Platform Trial - Regimen C CNM-Au8", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Amyotrophic Lateral Sclerosis" ], "interventions": [ { "name": "CNM-Au8", "type": "DRUG" }, { "name": "Matching Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Merit E. Cudkowicz, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 161, "start_date": "2020-07-30", "completion_date": "2023-03-07", "has_results": true, "last_update_posted_date": "2023-07-25", "last_synced_at": "2026-10-22T23:53:50.225Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04414345" }, { "nct_id": "NCT01393444", "title": "ECoG Direct Brain Interface for Individuals With Upper Limb Paralysis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Tetraplegia", "Spinal Cord Injury", "Brachial Plexus Injury", "Muscular Dystrophy", "ALS", "Brainstem Stroke" ], "interventions": [ { "name": "Implantation of ECoG sensors on the brain surface", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Pittsburgh", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 6, "start_date": "2011-05", "completion_date": "2015-04", "has_results": true, "last_update_posted_date": "2016-12-12", "last_synced_at": "2026-10-22T23:53:50.225Z", "location_count": 1, "location_summary": "Pittsburgh, Pennsylvania", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01393444" } ] }