{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=ARX",
    "query": {
      "condition": "ARX"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T02:00:38.496Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00612534",
      "title": "A Multicenter, Randomized, Placebo-Controlled Phase 2 Study to Evaluate the Clinical Efficacy, Safety, and Tolerability of ARX-F01 Sublingual Sufentanil in Patients Undergoing Elective Unilateral Total Knee Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Post Operative Pain"
      ],
      "interventions": [
        {
          "name": "Sufentanil NanoTab",
          "type": "DRUG"
        },
        {
          "name": "Placebo NanoTab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Talphera, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "45 Years to 80 Years"
      },
      "enrollment_count": 94,
      "start_date": "2008-03",
      "completion_date": "2008-10",
      "has_results": true,
      "last_update_posted_date": "2014-02-17",
      "last_synced_at": "2026-05-22T02:00:38.496Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00612534"
    },
    {
      "nct_id": "NCT00833040",
      "title": "A Study for the Evaluation of the Safety, Tolerability, and Efficacy of ARX-F02 (Sufentanil NanoTab) Compared to Placebo in the Treatment of Cancer Breakthrough Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cancer",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Sublingual sufentanil NanoTabs™ and placebo NanoTabs™",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Talphera, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2009-04",
      "completion_date": "2010-03",
      "has_results": true,
      "last_update_posted_date": "2015-01-01",
      "last_synced_at": "2026-05-22T02:00:38.496Z",
      "location_count": 13,
      "location_summary": "Montebello, California • Jacksonville, Florida • Lakeland, Florida + 10 more",
      "locations": [
        {
          "city": "Montebello",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Lakeland",
          "state": "Florida"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Venice",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00833040"
    },
    {
      "nct_id": "NCT00718081",
      "title": "A Multicenter, Randomized, Placebo-Controlled Phase 2 Study to Evaluate the Clinical Efficacy, Safety, and Tolerability of ARX-F01 Sublingual Sufentanil in Patients Undergoing Major Abdominal Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Major Upper or Lower Abdominal Surgery"
      ],
      "interventions": [
        {
          "name": "Oral sufentanil",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Talphera, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 88,
      "start_date": "2008-08",
      "completion_date": "2009-03",
      "has_results": true,
      "last_update_posted_date": "2015-01-22",
      "last_synced_at": "2026-05-22T02:00:38.496Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00718081"
    },
    {
      "nct_id": "NCT02952534",
      "title": "A Study of Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Metastatic Castration Resistant Prostate Cancer"
      ],
      "interventions": [
        {
          "name": "Rucaparib",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "pharmaand GmbH",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 277,
      "start_date": "2017-02-15",
      "completion_date": "2021-07-27",
      "has_results": true,
      "last_update_posted_date": "2023-06-09",
      "last_synced_at": "2026-05-22T02:00:38.496Z",
      "location_count": 58,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 47 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02952534"
    },
    {
      "nct_id": "NCT00859313",
      "title": "An Open-Label Functionality, Safety and Efficacy Study in Patients Undergoing Elective Unilateral Knee Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pain, Postoperative"
      ],
      "interventions": [
        {
          "name": "Sufentanil NanoTab PCA System/15 mcg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Talphera, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "45 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2009-04",
      "completion_date": "2009-08",
      "has_results": true,
      "last_update_posted_date": "2012-03-01",
      "last_synced_at": "2026-05-22T02:00:38.496Z",
      "location_count": 3,
      "location_summary": "Birmingham, Alabama • Vero Beach, Florida • Houston, Texas",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Vero Beach",
          "state": "Florida"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00859313"
    },
    {
      "nct_id": "NCT01238250",
      "title": "Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "16P11.2 Deletion Syndrome",
        "16p11.2 Duplications",
        "1Q21.1 Deletion",
        "1Q21.1 Microduplication Syndrome (Disorder)",
        "ACTL6B",
        "ADNP",
        "AHDC1",
        "ANK2",
        "ANKRD11",
        "ARID1B",
        "ASH1L",
        "BCL11A",
        "CHAMP1",
        "CHD2",
        "CHD8",
        "CSNK2A1",
        "CTBP1",
        "CTNNB1 Gene Mutation",
        "CUL3",
        "DDX3X",
        "DNMT3A",
        "DSCAM",
        "DYRK1A",
        "FOXP1",
        "GRIN2A",
        "GRIN2B",
        "HIVEP2-Related Intellectual Disability",
        "HNRNPH2",
        "KATNAL2",
        "KDM5B",
        "KDM6B",
        "KMT2C Gene Mutation",
        "KMT2E",
        "KMT5B",
        "MBD5",
        "MED13L",
        "PACS1",
        "PPP2R5D-Related Intellectual Disability",
        "PTCHD1",
        "REST",
        "SCN2A Encephalopathy",
        "SETBP1 Gene Mutation",
        "SETD5",
        "SMARCA4 Gene Mutation",
        "SMARCC2",
        "STXBP1 Encephalopathy With Epilepsy",
        "SYNGAP1-Related Intellectual Disability",
        "TBR1",
        "ARHGEF9",
        "HNRNPU",
        "PPP3CA",
        "PPP2R1A",
        "SLC6A1",
        "2p16.3 Deletions",
        "5q35 Deletions",
        "5q35 Duplications",
        "7q11.23 Duplications",
        "15Q13.3 Deletion Syndrome",
        "16p11.2 Triplications",
        "16P12.2 Microdeletion",
        "16P13.11 Microdeletion Syndrome (Disorder)",
        "17Q12 Microdeletion Syndrome (Disorder)",
        "17Q12 Duplication Syndrome",
        "17Q21.31 Deletion Syndrome",
        "17q21.3 Duplications",
        "ACTB",
        "ADSL",
        "AFF2",
        "ALDH5A1",
        "ANK3",
        "ARX",
        "ATRX Gene Mutation",
        "AUTS2 Syndrome",
        "BCKDK",
        "BRSK2",
        "CACNA1C",
        "CAPRIN1",
        "CASK",
        "CASZ1",
        "CHD3",
        "CIC",
        "CNOT3",
        "CREBBP Gene Mutation",
        "CSDE1",
        "CTCF",
        "DEAF1",
        "DHCR7",
        "DLG4",
        "EBF3",
        "EHMT1",
        "EP300 Gene Mutation",
        "GIGYF1",
        "GRIN1",
        "GRIN2D",
        "IQSEC2-Related Syndromic Intellectual Disability",
        "IRF2BPL",
        "KANSL1",
        "KCNB1",
        "KDM3B",
        "NEXMIF",
        "KMT2A",
        "MBOAT7",
        "MEIS2",
        "MYT1L",
        "NAA15",
        "NBEA",
        "NCKAP1",
        "NIPBL",
        "NLGN2",
        "NLGN3",
        "NLGN4X",
        "NR4A2",
        "NRXN1",
        "NRXN2",
        "NSD1 Gene Mutation",
        "PHF21A",
        "PHF3",
        "PHIP",
        "POMGNT1",
        "PSMD12",
        "RELN",
        "RERE",
        "RFX3",
        "RIMS1",
        "RORB",
        "SCN1A",
        "SETD2 Gene Mutation",
        "SHANK2",
        "SIN3A",
        "SLC9A6",
        "SON",
        "SOX5",
        "SPAST",
        "SRCAP",
        "TAOK1",
        "TANC2",
        "TCF20",
        "TLK2",
        "TRIO",
        "TRIP12",
        "UPF3B",
        "USP9X",
        "VPS13B",
        "WAC",
        "WDFY3",
        "ZBTB20",
        "ZNF292",
        "ZNF462",
        "2Q37 Deletion Syndrome",
        "9q34 Duplications",
        "15q15 Deletions",
        "15Q24 Deletion",
        "NR3C2",
        "SYNCRIP",
        "2q34 Duplication",
        "2q37.3 Deletion",
        "6q16 Deletion",
        "15q11.2 BP1-BP2 Deletion",
        "16p13.3 Deletion",
        "17Q11.2 Microduplication Syndrome (Disorder)",
        "17p13.3",
        "Xq28 Duplication",
        "CLCN4",
        "CSNK2B",
        "DYNC1H1",
        "EIF3F",
        "GNB1",
        "MED13",
        "MEF2C",
        "RALGAPB",
        "SCN1B",
        "YY1",
        "Xp11.22 Duplication",
        "PACS2",
        "MAOA",
        "MAOB",
        "HNRNPC",
        "HNRNPD",
        "HNRNPK",
        "HNRNPR",
        "HNRNPUL2",
        "5P Deletion Syndrome",
        "TCF7L2 Gene Mutation",
        "HECW2"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Simons Searchlight",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 100000,
      "start_date": "2010-10",
      "completion_date": "2050-10",
      "has_results": false,
      "last_update_posted_date": "2025-06-06",
      "last_synced_at": "2026-05-22T02:00:38.496Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Lewisburg, Pennsylvania",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Lewisburg",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01238250"
    },
    {
      "nct_id": "NCT00894699",
      "title": "A Study to Evaluate the Clinical Efficacy, Safety and Tolerability of ARX-F03 Sublingual Sufentanil/Triazolam NanoTab™ in Patients Undergoing an Elective Abdominal Liposuction Procedure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Sedation",
        "Anxiety",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Sublingual Sufentanil/Triazolam NanoTab™ (ARX-F03)",
          "type": "DRUG"
        },
        {
          "name": "Placebo NanoTab™",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Talphera, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 40,
      "start_date": "2009-06",
      "completion_date": "2009-09",
      "has_results": true,
      "last_update_posted_date": "2014-06-25",
      "last_synced_at": "2026-05-22T02:00:38.496Z",
      "location_count": 1,
      "location_summary": "Pasadena, California",
      "locations": [
        {
          "city": "Pasadena",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00894699"
    },
    {
      "nct_id": "NCT05787587",
      "title": "A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Advanced or Metastatic Solid Tumors",
        "Breast Cancer",
        "Ovarian Cancer",
        "Prostate Cancer",
        "Endometrial Cancer",
        "Colorectal Cancer",
        "Head and Neck Cancers",
        "Extensive Stage Small Cell Lung Cancer (ES-SCLC)",
        "NSCLC"
      ],
      "interventions": [
        {
          "name": "IDE-161",
          "type": "DRUG"
        },
        {
          "name": "Pembrolizumab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "IDEAYA Biosciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 216,
      "start_date": "2023-04-18",
      "completion_date": "2027-05",
      "has_results": false,
      "last_update_posted_date": "2026-02-09",
      "last_synced_at": "2026-05-22T02:00:38.496Z",
      "location_count": 27,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Newport Beach, California + 22 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05787587"
    }
  ]
}