{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=AV+Node+Disease",
    "query": {
      "condition": "AV Node Disease"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=AV+Node+Disease&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T08:27:56.137Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00284830",
      "title": "SAVEPACe - Search AV Extension and Managed Ventricular Pacing for Promoting Atrio-Ventricular Conduction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sick Sinus Syndrome",
        "Heart Failure, Congestive",
        "Atrial Fibrillation",
        "Bradycardia",
        "Ventricular Dysfunction"
      ],
      "interventions": [
        {
          "name": "Implantable Pulse Generators",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Cardiac Rhythm and Heart Failure",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1070,
      "start_date": "2003-01",
      "completion_date": "2008-02",
      "has_results": false,
      "last_update_posted_date": "2008-02-29",
      "last_synced_at": "2026-07-24T08:27:56.137Z",
      "location_count": 63,
      "location_summary": "Phoenix, Arizona • Scottsdale, Arizona • Conway, Arkansas + 60 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Conway",
          "state": "Arkansas"
        },
        {
          "city": "Glendale",
          "state": "California"
        },
        {
          "city": "La Mesa",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00284830"
    },
    {
      "nct_id": "NCT03903107",
      "title": "The Fluoroless-CSP Trial Using Electroanatomic Mapping",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sinus Node Dysfunction",
        "Heart Block AV",
        "LBBB",
        "Heart Failure, Systolic"
      ],
      "interventions": [
        {
          "name": "Conventional fluoroscopy guided Conduction System Pacing(CSP)",
          "type": "PROCEDURE"
        },
        {
          "name": "Electroanatomic Mapping (Fluoroless) guided Conduction System Pacing(CSP)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2020-10-26",
      "completion_date": "2024-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-02-28",
      "last_synced_at": "2026-07-24T08:27:56.137Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03903107"
    },
    {
      "nct_id": "NCT01170611",
      "title": "Prevention of Atrial Arrhythmia in Patients Without Atrioventricular (AV) Conduction Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Sinus Node Dysfunction",
        "Brady Tachy Syndrome"
      ],
      "interventions": [
        {
          "name": "PACEMAKER SYMPHONY 2550",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "LivaNova",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2004-07",
      "completion_date": "2007-01",
      "has_results": false,
      "last_update_posted_date": "2010-07-27",
      "last_synced_at": "2026-07-24T08:27:56.137Z",
      "location_count": 10,
      "location_summary": "Birmingham, Alabama • Mesa, Arizona • Los Angeles, California + 7 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Jackson",
          "state": "Mississippi"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01170611"
    },
    {
      "nct_id": "NCT03850808",
      "title": "LV Dysfunction Following Pacemaker Placement",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 500,
      "start_date": "2013-09",
      "completion_date": "2018-09",
      "has_results": false,
      "last_update_posted_date": "2019-02-25",
      "last_synced_at": "2026-07-24T08:27:56.137Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03850808"
    },
    {
      "nct_id": "NCT00356057",
      "title": "Investigational Device Exemption (IDE) Study for the Approval of Closed Loop Stimulation (CLS) and Cardiac Resyncronization Pacing Therapies (CRT) for the Treatment of Atrial Fibrillation (AF) With Ablate and Pace",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atrial Fibrillation",
        "Congestive Heart Failure"
      ],
      "interventions": [
        {
          "name": "Protos DR/CLS and Stratos LV CRT pacemakers",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Biotronik, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 153,
      "start_date": "2004-12",
      "completion_date": "2008-06",
      "has_results": true,
      "last_update_posted_date": "2018-02-27",
      "last_synced_at": "2026-07-24T08:27:56.137Z",
      "location_count": 10,
      "location_summary": "Birmingham, Alabama • Lake Charles, Louisiana • Boston, Massachusetts + 7 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Lake Charles",
          "state": "Louisiana"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Lapeer",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00356057"
    },
    {
      "nct_id": "NCT06445439",
      "title": "Optimal Pacing Rate for Cardiac Resynchronization Therapy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atrial Fibrillation, Persistent"
      ],
      "interventions": [
        {
          "name": "Pacing rate of 80 bpm",
          "type": "DEVICE"
        },
        {
          "name": "Pacing rate of 60 bpm",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medstar Health Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 60,
      "start_date": "2023-12-19",
      "completion_date": "2025-08",
      "has_results": false,
      "last_update_posted_date": "2024-10-15",
      "last_synced_at": "2026-07-24T08:27:56.137Z",
      "location_count": 5,
      "location_summary": "Washington D.C., District of Columbia • Baltimore, Maryland • Clinton, Maryland + 1 more",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Clinton",
          "state": "Maryland"
        },
        {
          "city": "Fairfax",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06445439"
    },
    {
      "nct_id": "NCT04245345",
      "title": "Accelerometer Sensing for Micra AV Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "AV Block",
        "AV Block Complete",
        "3rd Degree Heart Block",
        "Complete Heart Block"
      ],
      "interventions": [
        {
          "name": "Accelerometer Sensing for Micra AV Study",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Cardiac Rhythm and Heart Failure",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 157,
      "start_date": "2020-06-09",
      "completion_date": "2022-01-10",
      "has_results": true,
      "last_update_posted_date": "2023-02-23",
      "last_synced_at": "2026-07-24T08:27:56.137Z",
      "location_count": 18,
      "location_summary": "Stockton, California • Jacksonville, Florida • Leesburg, Florida + 14 more",
      "locations": [
        {
          "city": "Stockton",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Leesburg",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Manchester",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04245345"
    },
    {
      "nct_id": "NCT00589303",
      "title": "AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation - Pilot Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Atrial Fibrillation",
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "FDA approved rate and rhythm control drugs",
          "type": "DRUG"
        },
        {
          "name": "AV Node ablation and device implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 27,
      "start_date": "2007-12",
      "completion_date": "2011-07",
      "has_results": true,
      "last_update_posted_date": "2013-04-04",
      "last_synced_at": "2026-07-24T08:27:56.137Z",
      "location_count": 5,
      "location_summary": "Scottsdale, Arizona • Evansville, Indiana • Rochester, Minnesota + 2 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Evansville",
          "state": "Indiana"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Chattanooga",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00589303"
    },
    {
      "nct_id": "NCT06690333",
      "title": "Efficacy and Safety of Leadless Pacemakers Versus Left Bundle Area Pacing - A Preliminary Exploration",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pacemaker Implantation",
        "AV Node Disease"
      ],
      "interventions": [
        {
          "name": "Pacemaker",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "NCH Healthcare System, Inc. dba Naples Comprehensive Health and dba NCH",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 75,
      "start_date": "2024-11-05",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-05-30",
      "last_synced_at": "2026-07-24T08:27:56.137Z",
      "location_count": 2,
      "location_summary": "Naples, Florida • Boston, Massachusetts",
      "locations": [
        {
          "city": "Naples",
          "state": "Florida"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06690333"
    },
    {
      "nct_id": "NCT04232371",
      "title": "Treatment Study of AV Node Reentry Tachycardia",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Supraventricular Tachycardia"
      ],
      "interventions": [
        {
          "name": "New Ablation Technique",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard Ablation Technique",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Jeffrey Moak",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "Up to 21 Years"
      },
      "enrollment_count": 300,
      "start_date": "2020-07-15",
      "completion_date": "2023-03",
      "has_results": false,
      "last_update_posted_date": "2022-07-28",
      "last_synced_at": "2026-07-24T08:27:56.137Z",
      "location_count": 5,
      "location_summary": "Washington D.C., District of Columbia • Hollywood, Florida • Iowa City, Iowa + 2 more",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04232371"
    }
  ]
}