{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Abdominal+Wall+Defect",
    "query": {
      "condition": "Abdominal Wall Defect"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Abdominal+Wall+Defect&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:18:06.612Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02416674",
      "title": "Vascularized Composite Allotransplantation for Treatment of Abdominal Wall Defects",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Abdominal Wall Defect"
      ],
      "interventions": [
        {
          "name": "abdominal wall transplantation",
          "type": "PROCEDURE"
        },
        {
          "name": "Immunosuppressive Agents",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 10,
      "start_date": "2015-03-01",
      "completion_date": "2025-02",
      "has_results": false,
      "last_update_posted_date": "2023-07-27",
      "last_synced_at": "2026-05-22T05:18:06.612Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02416674"
    },
    {
      "nct_id": "NCT05704257",
      "title": "Fetal Repair of Complex Gastroschisis: A Safety and Feasibility Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastroschisis"
      ],
      "interventions": [
        {
          "name": "fetoscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 10,
      "start_date": "2023-10-20",
      "completion_date": "2029-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-23",
      "last_synced_at": "2026-05-22T05:18:06.612Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05704257"
    },
    {
      "nct_id": "NCT01214252",
      "title": "A Retrospective Study Evaluating the Use of Permacol Surgical Implant in the Repair of Abdominal Wall Defects",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Abdominal Wall Defects"
      ],
      "interventions": [
        {
          "name": "Permacol Surgical Implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic - MITG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 343,
      "start_date": "2010-10",
      "completion_date": "2012-01",
      "has_results": true,
      "last_update_posted_date": "2014-05-09",
      "last_synced_at": "2026-05-22T05:18:06.612Z",
      "location_count": 1,
      "location_summary": "Bedford, Massachusetts",
      "locations": [
        {
          "city": "Bedford",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01214252"
    },
    {
      "nct_id": "NCT01364233",
      "title": "Safety Study of MotifMESH (cPTFE) in Abdominal Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hernia"
      ],
      "interventions": [
        {
          "name": "MotifMESH",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medline Industries",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2011-05",
      "completion_date": "2014-03",
      "has_results": true,
      "last_update_posted_date": "2019-02-26",
      "last_synced_at": "2026-05-22T05:18:06.612Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01364233"
    },
    {
      "nct_id": "NCT02228889",
      "title": "RCT of Two Noncrosslinked Porcine Acellular Dermal Matrices in Ab Wall Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hernia, Ventral",
        "Intestinal Fistula",
        "Fibromatosis, Abdominal"
      ],
      "interventions": [
        {
          "name": "Abdominal wall reconstruction with Strattice",
          "type": "PROCEDURE"
        },
        {
          "name": "Assess pain intensity at last office visit preoperatively",
          "type": "OTHER"
        },
        {
          "name": "Assess pain interference at last office visit preoperatively",
          "type": "OTHER"
        },
        {
          "name": "Assess physical functioning at last office visit preoperatively",
          "type": "OTHER"
        },
        {
          "name": "Assess patient quality of life at last office visit preoperatively",
          "type": "OTHER"
        },
        {
          "name": "Assess patient pain intensity postoperatively",
          "type": "OTHER"
        },
        {
          "name": "Assess pain interference postoperatively",
          "type": "OTHER"
        },
        {
          "name": "Assess physical functioning postoperatively",
          "type": "OTHER"
        },
        {
          "name": "Assess quality of life postoperatively",
          "type": "OTHER"
        },
        {
          "name": "Assess hernia recurrence at 30 days postoperatively",
          "type": "OTHER"
        },
        {
          "name": "Assess bulge at 30 days postoperatively",
          "type": "OTHER"
        },
        {
          "name": "Assess Surgical Site Occurrences at 30 days postoperatively",
          "type": "OTHER"
        },
        {
          "name": "Assess hernia recurrence at 1 year postoperatively",
          "type": "OTHER"
        },
        {
          "name": "Assess bulge at 1 year postoperatively",
          "type": "OTHER"
        },
        {
          "name": "Assess Surgical Site Occurrences at 1 year postoperatively",
          "type": "OTHER"
        },
        {
          "name": "Assess overall complications at 30 days postoperatively",
          "type": "OTHER"
        },
        {
          "name": "Assess overall complications at 1 year postoperatively",
          "type": "OTHER"
        },
        {
          "name": "Abdominal wall reconstruction with XenMatrix",
          "type": "PROCEDURE"
        },
        {
          "name": "Strattice",
          "type": "DEVICE"
        },
        {
          "name": "XenMatrix",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Jeffrey Janis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 46,
      "start_date": "2015-01",
      "completion_date": "2025-03-27",
      "has_results": true,
      "last_update_posted_date": "2025-06-06",
      "last_synced_at": "2026-05-22T05:18:06.612Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02228889"
    },
    {
      "nct_id": "NCT05579652",
      "title": "Change in Fascial Tension in Open Abdomens",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Abdominal Wall Defect",
        "Incisional Hernia"
      ],
      "interventions": [
        {
          "name": "Abdominal tension measurement",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Benjamin T. Miller",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2022-10-17",
      "completion_date": "2024-03-29",
      "has_results": false,
      "last_update_posted_date": "2024-05-23",
      "last_synced_at": "2026-05-22T05:18:06.612Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05579652"
    },
    {
      "nct_id": "NCT03241719",
      "title": "Novel Strategies to Improve Immunomodulation and Non-invasive Clinical Monitoring in VCA",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Amputation, Traumatic",
        "Amputation;Traumatic;Old",
        "Face Injury",
        "Face; Deformity",
        "Abdominal Wall Defect"
      ],
      "interventions": [
        {
          "name": "IL-2",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 2,
      "start_date": "2017-10-17",
      "completion_date": "2021-07-21",
      "has_results": false,
      "last_update_posted_date": "2021-07-28",
      "last_synced_at": "2026-05-22T05:18:06.612Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03241719"
    },
    {
      "nct_id": "NCT01794338",
      "title": "The Use of Biologic Mesh vs Bioabsorbable Mesh During Ventral Hernia Repair in At-risk Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ventral Hernia"
      ],
      "interventions": [
        {
          "name": "Strattice Arm",
          "type": "DEVICE"
        },
        {
          "name": "Bio-A Arm",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 28,
      "start_date": "2012-11",
      "completion_date": "2017-07-21",
      "has_results": true,
      "last_update_posted_date": "2022-08-15",
      "last_synced_at": "2026-05-22T05:18:06.612Z",
      "location_count": 1,
      "location_summary": "Charlotte, North Carolina",
      "locations": [
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01794338"
    },
    {
      "nct_id": "NCT00820040",
      "title": "Feasibility of Permacol Use in Infected Fields",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Hernia"
      ],
      "interventions": [
        {
          "name": "acellular porcine dermal collagen mesh",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic - MITG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 10,
      "start_date": "2009-07",
      "completion_date": "2011-08",
      "has_results": true,
      "last_update_posted_date": "2020-12-09",
      "last_synced_at": "2026-05-22T05:18:06.612Z",
      "location_count": 3,
      "location_summary": "Lexington, Kentucky • Albany, New York • Greenville, South Carolina",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Albany",
          "state": "New York"
        },
        {
          "city": "Greenville",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00820040"
    },
    {
      "nct_id": "NCT01644695",
      "title": "Review of Complex Recurrent Hernia Repair",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Recurrent Hernia"
      ],
      "interventions": [
        {
          "name": "Bony Anchoring Reinforcement System",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Institute For Advanced Reconstruction",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 85,
      "start_date": "2011-10",
      "completion_date": "2020-01",
      "has_results": true,
      "last_update_posted_date": "2012-10-15",
      "last_synced_at": "2026-05-22T05:18:06.612Z",
      "location_count": 1,
      "location_summary": "Shrewsbury, New Jersey",
      "locations": [
        {
          "city": "Shrewsbury",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01644695"
    }
  ]
}