{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Above+Knee+Amputation&page=2",
    "query": {
      "condition": "Above Knee Amputation",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Above+Knee+Amputation&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T12:28:36.756Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07664995",
      "title": "Determining the Effects of Ischemic Conditioning and Neuromuscular Electrical Stimulation on Overall Function After Lower Limb Amputation",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Limb Amputation Above Knee",
        "Below Knee Amputation"
      ],
      "interventions": [
        {
          "name": "Blood pressure cuff",
          "type": "DEVICE"
        },
        {
          "name": "Neuromuscular Electrical Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2026-07-01",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-24",
      "last_synced_at": "2026-07-22T12:28:36.756Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07664995"
    },
    {
      "nct_id": "NCT07204912",
      "title": "Evaluation of a Neural-Controlled Powered Prosthesis Across Diverse Real-World Tasks",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Transfemoral Amputation"
      ],
      "interventions": [
        {
          "name": "MIT Powered Leg",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 10,
      "start_date": "2025-05-31",
      "completion_date": "2028-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-02",
      "last_synced_at": "2026-07-22T12:28:36.756Z",
      "location_count": 1,
      "location_summary": "Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07204912"
    },
    {
      "nct_id": "NCT07613502",
      "title": "Bio Leg: Advancing Mobility (BAM)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation of Lower Limb Above Knee",
        "Amputee",
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Bio Leg",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 12,
      "start_date": "2026-06-01",
      "completion_date": "2028-07",
      "has_results": false,
      "last_update_posted_date": "2026-07-06",
      "last_synced_at": "2026-07-22T12:28:36.756Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07613502"
    },
    {
      "nct_id": "NCT04038151",
      "title": "Intuitive Control of a Hybrid Prosthetic Leg During Ambulation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Hybrid Leg",
          "type": "DEVICE"
        },
        {
          "name": "Prescribed Passive Prosthesis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Shirley Ryan AbilityLab",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "18 Years to 95 Years"
      },
      "enrollment_count": 20,
      "start_date": "2018-12-01",
      "completion_date": "2025-06-30",
      "has_results": false,
      "last_update_posted_date": "2024-05-17",
      "last_synced_at": "2026-07-22T12:28:36.756Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04038151"
    },
    {
      "nct_id": "NCT06194838",
      "title": "Clinical Outcomes With Non-Powered vs. Powered Prosthetic Knees by K2-level Amputees",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation",
        "Amputation; Traumatic, Leg, Lower",
        "Limb; Absence, Congenital, Lower",
        "Prosthesis User",
        "Lower Limb Amputation Above Knee (Injury)",
        "Amputation; Traumatic, Leg: Thigh, Between Hip and Knee"
      ],
      "interventions": [
        {
          "name": "Ossur Power Knee",
          "type": "DEVICE"
        },
        {
          "name": "Reboocon Intuy Knee",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Liberating Technologies, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 26,
      "start_date": "2023-09-12",
      "completion_date": "2026-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-09-03",
      "last_synced_at": "2026-07-22T12:28:36.756Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06194838"
    },
    {
      "nct_id": "NCT02685098",
      "title": "A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Ischemia",
        "Peripheral Arterial Disease",
        "Peripheral Vascular Disease",
        "Vascular Disease",
        "Arterial Occlusive Disease",
        "Arteriosclerosis",
        "Atherosclerosis",
        "Cardiovascular Disease",
        "Pathologic Processes",
        "Orthopedic Procedures",
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Allogeneic bone marrow derived mesenchymal stem cells",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "40 Years to 90 Years"
      },
      "enrollment_count": 81,
      "start_date": "2017-01-23",
      "completion_date": "2023-10-03",
      "has_results": false,
      "last_update_posted_date": "2025-09-23",
      "last_synced_at": "2026-07-22T12:28:36.756Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02685098"
    },
    {
      "nct_id": "NCT04239222",
      "title": "Feasibility Study to Evaluate a New Energy Storage and Return Prosthetic Foot",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Limb Amputation Below Knee (Injury)",
        "Lower Limb Amputation Above Knee (Injury)",
        "Lower Limb Amputation Knee"
      ],
      "interventions": [
        {
          "name": "Revo-M",
          "type": "DEVICE"
        },
        {
          "name": "Taleo",
          "type": "DEVICE"
        },
        {
          "name": "Proflex XC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Otto Bock Healthcare Products GmbH",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 27,
      "start_date": "2020-03-10",
      "completion_date": "2022-03-11",
      "has_results": true,
      "last_update_posted_date": "2024-09-23",
      "last_synced_at": "2026-07-22T12:28:36.756Z",
      "location_count": 4,
      "location_summary": "Mesa, Arizona • Linthicum, Maryland • Dayton, Ohio + 1 more",
      "locations": [
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Linthicum",
          "state": "Maryland"
        },
        {
          "city": "Dayton",
          "state": "Ohio"
        },
        {
          "city": "Exton",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04239222"
    },
    {
      "nct_id": "NCT05126485",
      "title": "Biofeedback Retention in Individuals With AKA",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Amputation of Knee",
        "Back Pain",
        "Osteo Arthritis Knee"
      ],
      "interventions": [
        {
          "name": "Haptic Biofeedback from SageMotion Biofeedback System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "San Jose State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 35,
      "start_date": "2021-09-15",
      "completion_date": "2024-09-14",
      "has_results": false,
      "last_update_posted_date": "2023-10-02",
      "last_synced_at": "2026-07-22T12:28:36.756Z",
      "location_count": 2,
      "location_summary": "Palo Alto, California • San Francisco, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05126485"
    },
    {
      "nct_id": "NCT03446131",
      "title": "Improved Training Program for Fall Prevention of War Fighters",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Limb Injury"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 45,
      "start_date": "2018-03-12",
      "completion_date": "2020-12-31",
      "has_results": false,
      "last_update_posted_date": "2021-01-07",
      "last_synced_at": "2026-07-22T12:28:36.756Z",
      "location_count": 4,
      "location_summary": "San Diego, California • Bethesda, Maryland • Rochester, Minnesota + 1 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03446131"
    },
    {
      "nct_id": "NCT05925712",
      "title": "Aerofit Post Market Investigation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Transfemoral Amputation",
        "Amputation",
        "Skin Health"
      ],
      "interventions": [
        {
          "name": "AeroFit Seal-In Liner / Socket",
          "type": "DEVICE"
        },
        {
          "name": "Seal-In Silicone Liner",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Össur Iceland ehf",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 56,
      "start_date": "2023-06-06",
      "completion_date": "2024-05-31",
      "has_results": false,
      "last_update_posted_date": "2024-10-08",
      "last_synced_at": "2026-07-22T12:28:36.756Z",
      "location_count": 7,
      "location_summary": "Gainesville, Florida • Indianapolis, Indiana • Bay City, Michigan + 3 more",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Bay City",
          "state": "Michigan"
        },
        {
          "city": "Perrysburg",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05925712"
    }
  ]
}