{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Acid+Reflux&page=17",
    "query": {
      "condition": "Acid Reflux",
      "page": 17
    },
    "page_size": 10
  },
  "pagination": {
    "page": 17,
    "page_size": 10,
    "total_count": 498,
    "total_pages": 50,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Acid+Reflux&page=18&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Acid+Reflux&page=16&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-19T20:51:21.365Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05455359",
      "title": "Gastrointestinal Dysmotility on Aspiration Risk",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Esophageal Motility Disorders",
        "Gastric Motor Dysfunction",
        "Aspiration Pneumonia",
        "Gastro Esophageal Reflux"
      ],
      "interventions": [
        {
          "name": "Prucalopride",
          "type": "DRUG"
        },
        {
          "name": "Famotidine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "5 Years to 21 Years"
      },
      "enrollment_count": 120,
      "start_date": "2025-02-13",
      "completion_date": "2027-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-03",
      "last_synced_at": "2026-10-19T20:51:21.365Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05455359"
    },
    {
      "nct_id": "NCT02030925",
      "title": "Ph2a Study to Evaluate IW-3718 in Patients With Gastroesophageal Reflux Not Completely Responsive to Proton Pump Inhibitors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Gastroesophageal Reflux"
      ],
      "interventions": [
        {
          "name": "IW-3718",
          "type": "DRUG"
        },
        {
          "name": "Matching Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ironwood Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 93,
      "start_date": "2014-02",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2016-08-01",
      "last_synced_at": "2026-10-19T20:51:21.365Z",
      "location_count": 10,
      "location_summary": "North Little Rock, Arkansas • Anaheim, California • Monroe, Louisiana + 7 more",
      "locations": [
        {
          "city": "North Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Monroe",
          "state": "Louisiana"
        },
        {
          "city": "Chesterfield",
          "state": "Michigan"
        },
        {
          "city": "Raleigh",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02030925"
    },
    {
      "nct_id": "NCT04846010",
      "title": "Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Sequelae of; Infection",
        "Post Infection Glomerulonephritis",
        "Post-Infectious Peripheral Neuralgia",
        "Post-Infectious Disorder (Disorder)",
        "Post-Infectious Arthritis",
        "Post-Infectious Polyneuritis",
        "Post-Infectious Parkinsonism",
        "Post-Infectious Hypothyroidism",
        "Post Infectious Osteoarthritis",
        "Anxiety Disorders",
        "Depression",
        "Depression, Anxiety",
        "Depression, Bipolar",
        "Insomnia",
        "GERD",
        "Gastro Esophageal Reflux",
        "Hepatitis",
        "Glomerulonephritis"
      ],
      "interventions": [
        {
          "name": "PurWet",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "FurFat",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "PurApo",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "PurPhl",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "PurClo",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "PurInf",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Smoliv",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "All Natural Medicine Clinic, LLC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 2000,
      "start_date": "2021-03-01",
      "completion_date": "2022-10-01",
      "has_results": false,
      "last_update_posted_date": "2021-05-26",
      "last_synced_at": "2026-10-19T20:51:21.365Z",
      "location_count": 1,
      "location_summary": "Rockville, Maryland",
      "locations": [
        {
          "city": "Rockville",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04846010"
    },
    {
      "nct_id": "NCT00260585",
      "title": "Esophageal Cancer Risk Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Esophageal Cancer",
        "Gastroesophageal Reflux Disease (GERD)",
        "Esophageal Diseases",
        "Hiatal Hernia",
        "Esophageal Achalasia"
      ],
      "interventions": [
        {
          "name": "Survey of client health, personal habits, family history",
          "type": "PROCEDURE"
        },
        {
          "name": "Blood specimen for non-DNA and DNA parts",
          "type": "PROCEDURE"
        },
        {
          "name": "Biopsy of esophageal/stomach tissue, lymph nodes, tumor",
          "type": "PROCEDURE"
        },
        {
          "name": "Biopsies, oral (saliva) and/or secretions, washings or mucosal scrapings/brushing from routine clinical surveillance endoscopies",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 7000,
      "start_date": "1999-06",
      "completion_date": "2050-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-14",
      "last_synced_at": "2026-10-19T20:51:21.365Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00260585"
    },
    {
      "nct_id": "NCT00693225",
      "title": "Impact of Timing on the Efficacy of Zegerid 40 mg in Healing Reflux Esophagitis: A Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Erosive Esophagitis"
      ],
      "interventions": [
        {
          "name": "Omeprazole/sodium bicarbonate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yvonne Romero",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 91,
      "start_date": "2008-01",
      "completion_date": "2010-12",
      "has_results": true,
      "last_update_posted_date": "2012-09-20",
      "last_synced_at": "2026-10-19T20:51:21.365Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00693225"
    },
    {
      "nct_id": "NCT01865825",
      "title": "Proton Pump Inhibitor (PPI) Responsive Eosinophilic Esophagitis EoE: Gastroesophageal Reflux Disease (GERD) or Eosinophilic Esophagitis (EoE)?",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Erosive Esophagitis"
      ],
      "interventions": [
        {
          "name": "Esophageal Barium Xray",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "RADIATION"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2013-03",
      "completion_date": "2017-03",
      "has_results": false,
      "last_update_posted_date": "2017-03-22",
      "last_synced_at": "2026-10-19T20:51:21.365Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01865825"
    },
    {
      "nct_id": "NCT00307944",
      "title": "Study of Pantoprazole for Sleepiness Associated With Acid Reflux and Sleep Apnea",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Acid Reflux Disease",
        "Obstructive Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "Pantoprazole",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 68,
      "start_date": "2004-08",
      "completion_date": "2006-08",
      "has_results": false,
      "last_update_posted_date": "2007-12-12",
      "last_synced_at": "2026-10-19T20:51:21.365Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00307944"
    },
    {
      "nct_id": "NCT01374074",
      "title": "Racial Disparity in Barrett's Esophagus",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Barrett's Esophagus",
        "Gastroesophageal Reflux Disease (GERD)",
        "Intestinal Metaplasia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 255,
      "start_date": "2011-03",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2015-09-23",
      "last_synced_at": "2026-10-19T20:51:21.365Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01374074"
    },
    {
      "nct_id": "NCT01281618",
      "title": "Influence of Acid Reflux on Stromal Epithelial Interaction in Barrett's Esophagus",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Barrett's Esophagus"
      ],
      "interventions": [
        {
          "name": "24 hour pH study and upper endoscopy (EGD)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 48,
      "start_date": "2008-10",
      "completion_date": "2011-06",
      "has_results": false,
      "last_update_posted_date": "2013-05-06",
      "last_synced_at": "2026-10-19T20:51:21.365Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01281618"
    },
    {
      "nct_id": "NCT01755221",
      "title": "Positive Predictive Value of the Dx-pH Probe for Predicting PPI Response in LPR",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Laryngopharyngeal Reflux (LPR)",
        "Extraesophageal Reflux",
        "Reflux Laryngitis",
        "Posterior Laryngitis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 42,
      "start_date": "2012-08",
      "completion_date": "2016-08",
      "has_results": false,
      "last_update_posted_date": "2024-04-24",
      "last_synced_at": "2026-10-19T20:51:21.365Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01755221"
    }
  ]
}