{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Actinic+Keratoses&page=2",
    "query": {
      "condition": "Actinic Keratoses",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Actinic+Keratoses&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-21T23:29:13.809Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06851507",
      "title": "A Pilot Clinical Trial Comparing Topical Fluorouracil to Fluorouracil Plus Calcipotriene Field Treatments in Patients With Multiple Actinic Keratoses",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Multiple Actinic Keratoses"
      ],
      "interventions": [
        {
          "name": "Fluorouracil 5-FU",
          "type": "DRUG"
        },
        {
          "name": "Fluorouracil/Calcipotriene",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2025-10-06",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-13",
      "last_synced_at": "2026-05-21T23:29:13.809Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06851507"
    },
    {
      "nct_id": "NCT01302925",
      "title": "PEP005 Gel - Evaluation of Local Tolerability After Exposure to Ingenol Mebutate Gel Followed by Hand Washing in Healthy Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy",
        "Actinic Keratosis"
      ],
      "interventions": [
        {
          "name": "PEP005 Gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Peplin",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2011-02",
      "completion_date": "2011-03",
      "has_results": false,
      "last_update_posted_date": "2015-09-14",
      "last_synced_at": "2026-05-21T23:29:13.809Z",
      "location_count": 1,
      "location_summary": "Paramus, New Jersey",
      "locations": [
        {
          "city": "Paramus",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01302925"
    },
    {
      "nct_id": "NCT00814528",
      "title": "Photodynamic Therapy Mediated by Topical Application of 5- ALA for the Treatment of Actinic Keratoses",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Actinic Keratosis"
      ],
      "interventions": [
        {
          "name": "5-ALA plus Blu-Light",
          "type": "DRUG"
        },
        {
          "name": "5-FU, Imiquimod or treatment with cryotherapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "18 Years to 95 Years"
      },
      "enrollment_count": 0,
      "start_date": "2007-11",
      "completion_date": "2009-09",
      "has_results": false,
      "last_update_posted_date": "2018-09-10",
      "last_synced_at": "2026-05-21T23:29:13.809Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00814528"
    },
    {
      "nct_id": "NCT05359419",
      "title": "Comparison of Two Modes of Photodynamic Therapy for the Treatment of Actinic Keratosis on the Upper Extremities",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Skin Neoplasms"
      ],
      "interventions": [
        {
          "name": "aminolevulinic acid hydrochloride gel, 10%",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "aminolevulinic acid HCl topical solution, 20%",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Goldman, Butterwick, Fitzpatrick and Groff",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "35 Years to 85 Years"
      },
      "enrollment_count": 20,
      "start_date": "2022-05-15",
      "completion_date": "2023-12-30",
      "has_results": false,
      "last_update_posted_date": "2022-05-04",
      "last_synced_at": "2026-05-21T23:29:13.809Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05359419"
    },
    {
      "nct_id": "NCT03996252",
      "title": "Combination Topical Therapy for Treatment of Scalp Actinic Keratoses",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Actinic Keratoses"
      ],
      "interventions": [
        {
          "name": "Calcipotriene 0.005% Foam",
          "type": "DRUG"
        },
        {
          "name": "Efudex 5% Topical Cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tulane University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2019-07-01",
      "completion_date": "2020-06-08",
      "has_results": false,
      "last_update_posted_date": "2020-12-07",
      "last_synced_at": "2026-05-21T23:29:13.809Z",
      "location_count": 1,
      "location_summary": "New Orleans, Louisiana",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03996252"
    },
    {
      "nct_id": "NCT03116698",
      "title": "A Study to Evaluate Two Concentrations of DFD-07 Cream, in Subjects With Actinic Keratosis (AK) of the Face and/or Scalp Over a 12-week Treatment Period",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Actinic Keratosis (AK)"
      ],
      "interventions": [
        {
          "name": "Low dose DFD07 once daily",
          "type": "DRUG"
        },
        {
          "name": "High dose DFD07 once daily",
          "type": "DRUG"
        },
        {
          "name": "High dose DFD07 twice daily",
          "type": "DRUG"
        },
        {
          "name": "Placebo twice daily",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Dr. Reddy's Laboratories Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 240,
      "start_date": "2017-02-14",
      "completion_date": "2018-07-05",
      "has_results": true,
      "last_update_posted_date": "2019-04-24",
      "last_synced_at": "2026-05-21T23:29:13.809Z",
      "location_count": 20,
      "location_summary": "Cerritos, California • Fremont, California • Palm Springs, California + 14 more",
      "locations": [
        {
          "city": "Cerritos",
          "state": "California"
        },
        {
          "city": "Fremont",
          "state": "California"
        },
        {
          "city": "Palm Springs",
          "state": "California"
        },
        {
          "city": "Santa Ana",
          "state": "California"
        },
        {
          "city": "Boca Raton",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03116698"
    },
    {
      "nct_id": "NCT00304239",
      "title": "Metvix PDT Versus Vehicle PDT With Aktilite CL128 Lamp in Patients With Actinic Keratosis on the Face and Scalp",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Actinic Keratosis"
      ],
      "interventions": [
        {
          "name": "Metvix-PDT",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Vehicle-PDT",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Galderma R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 131,
      "start_date": "2006-03-13",
      "completion_date": "2007-01-23",
      "has_results": true,
      "last_update_posted_date": "2023-07-03",
      "last_synced_at": "2026-05-21T23:29:13.809Z",
      "location_count": 4,
      "location_summary": "Naperville, Illinois • Louisville, Kentucky • Portland, Oregon + 1 more",
      "locations": [
        {
          "city": "Naperville",
          "state": "Illinois"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00304239"
    },
    {
      "nct_id": "NCT02628236",
      "title": "Maximal Use Systemic Exposure Study of Levulan Kerastick (MUSE 2)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Keratosis, Actinic"
      ],
      "interventions": [
        {
          "name": "Aminolevulinic Acid (ALA)",
          "type": "DRUG"
        },
        {
          "name": "BLU-U",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "DUSA Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2016-02",
      "completion_date": "2016-07",
      "has_results": true,
      "last_update_posted_date": "2017-09-18",
      "last_synced_at": "2026-05-21T23:29:13.809Z",
      "location_count": 2,
      "location_summary": "Austin, Texas • College Station, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "College Station",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02628236"
    },
    {
      "nct_id": "NCT00306800",
      "title": "Metvix PDT Versus Vehicle PDT With Aktilite CL128 Lamp in Patients With Actinic Keratosis on the Face and Scalp",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Actinic Keratosis"
      ],
      "interventions": [
        {
          "name": "Photodynamic therapy with methyl aminolevulinate cream",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Galderma R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2007-09",
      "completion_date": "2007-10",
      "has_results": false,
      "last_update_posted_date": "2021-02-18",
      "last_synced_at": "2026-05-21T23:29:13.809Z",
      "location_count": 7,
      "location_summary": "St. Petersburg, Florida • New York, New York • Rochester, New York + 4 more",
      "locations": [
        {
          "city": "St. Petersburg",
          "state": "Florida"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Rochester",
          "state": "New York"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00306800"
    },
    {
      "nct_id": "NCT02126670",
      "title": "ACT01 in Combination With Comp01-04 in Patients With Actinic Keratosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Actinic Keratosis"
      ],
      "interventions": [
        {
          "name": "ACT01",
          "type": "DRUG"
        },
        {
          "name": "Comp01",
          "type": "DRUG"
        },
        {
          "name": "Comp02",
          "type": "DRUG"
        },
        {
          "name": "Comp03",
          "type": "DRUG"
        },
        {
          "name": "Comp04",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Promius Pharma, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "30 Years to 85 Years"
      },
      "enrollment_count": 100,
      "start_date": "2014-04",
      "completion_date": "2014-09",
      "has_results": true,
      "last_update_posted_date": "2016-02-22",
      "last_synced_at": "2026-05-21T23:29:13.809Z",
      "location_count": 4,
      "location_summary": "San Diego, California • Louisville, Kentucky • High Point, North Carolina + 1 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "High Point",
          "state": "North Carolina"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02126670"
    }
  ]
}