{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Actinic+Keratoses&page=6", "query": { "condition": "Actinic Keratoses", "page": 6 }, "page_size": 10 }, "pagination": { "page": 6, "page_size": 10, "total_count": 167, "total_pages": 17, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Actinic+Keratoses&page=7&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Actinic+Keratoses&page=5&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-14T18:20:25.611Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00948428", "title": "Bioequivalence of Generic Imiquimod Cream, 5% When Compared to Aldara™ (Imiquimod) Cream, 5% in the Treatment of Actinic Keratosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Actinic Keratoses" ], "interventions": [ { "name": "imiquimod", "type": "DRUG" }, { "name": "Aldara™", "type": "DRUG" }, { "name": "Vehicle Cream", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Actavis Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 462, "start_date": "2008-05", "completion_date": "2009-04", "has_results": true, "last_update_posted_date": "2020-09-04", "last_synced_at": "2026-10-14T18:20:25.611Z", "location_count": 20, "location_summary": "Hot Springs, Arkansas • Fresno, California • San Diego, California + 17 more", "locations": [ { "city": "Hot Springs", "state": "Arkansas" }, { "city": "Fresno", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00948428" }, { "nct_id": "NCT02628236", "title": "Maximal Use Systemic Exposure Study of Levulan Kerastick (MUSE 2)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Keratosis, Actinic" ], "interventions": [ { "name": "Aminolevulinic Acid (ALA)", "type": "DRUG" }, { "name": "BLU-U", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "DUSA Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 14, "start_date": "2016-02", "completion_date": "2016-07", "has_results": true, "last_update_posted_date": "2017-09-18", "last_synced_at": "2026-10-14T18:20:25.611Z", "location_count": 2, "location_summary": "Austin, Texas • College Station, Texas", "locations": [ { "city": "Austin", "state": "Texas" }, { "city": "College Station", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02628236" }, { "nct_id": "NCT02120456", "title": "Safety and Efficacy of Escalating Doses of LEO 43204 Applied Once Daily for Two Consecutive Days on Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic Keratosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Actinic Keratosis" ], "interventions": [ { "name": "LEO 43204", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "LEO Pharma", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 224, "start_date": "2014-05", "completion_date": "2015-05", "has_results": true, "last_update_posted_date": "2025-03-06", "last_synced_at": "2026-10-14T18:20:25.611Z", "location_count": 13, "location_summary": "Phoenix, Arizona • Lomita, California • San Diego, California + 9 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Lomita", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Coral Gables", "state": "Florida" }, { "city": "Ormond Beach", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02120456" }, { "nct_id": "NCT06461442", "title": "Efficacy and Safety of Cryotherapy Versus 5-Fluorouracil in the Treatment of Actinic Keratosis", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Actinic Keratoses" ], "interventions": [ { "name": "Cryotherapy", "type": "PROCEDURE" }, { "name": "5Fluorouracil", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DRUG" ], "sponsor": "University of California, Davis", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 73, "start_date": "2024-07-01", "completion_date": "2026-09-01", "has_results": false, "last_update_posted_date": "2026-07-06", "last_synced_at": "2026-10-14T18:20:25.611Z", "location_count": 1, "location_summary": "Sacramento, California", "locations": [ { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06461442" }, { "nct_id": "NCT02622594", "title": "Bilateral Comparison of Treatment of Facial Actinic Keratoses Using Microneedling and Photodynamic Therapy With Aminolevulinic Acid and Blue Light Versus Photodynamic Therapy With Aminolevulinic Acid and Blue Light Using Two Incubation Times", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Actinic Keratoses" ], "interventions": [ { "name": "Aminolevulinic Acid (ALA)", "type": "DRUG" }, { "name": "Environ Cosmetic Roller", "type": "DEVICE" }, { "name": "BLU-U IIlluminator", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Dermatology, Laser & Vein Specialists of the Carolinas", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2015-10", "completion_date": "2017-04-13", "has_results": false, "last_update_posted_date": "2017-07-19", "last_synced_at": "2026-10-14T18:20:25.611Z", "location_count": 1, "location_summary": "Charlotte, North Carolina", "locations": [ { "city": "Charlotte", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02622594" }, { "nct_id": "NCT00005097", "title": "Green Tea Extract in Treating Patients With Actinic Keratosis", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Non-melanomatous Skin Cancer" ], "interventions": [ { "name": "Polyphenon E and Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Frank Meyskens", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 88, "start_date": "1999-08", "completion_date": "2002-08", "has_results": false, "last_update_posted_date": "2018-04-05", "last_synced_at": "2026-10-14T18:20:25.611Z", "location_count": 1, "location_summary": "Orange, California", "locations": [ { "city": "Orange", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00005097" }, { "nct_id": "NCT00952783", "title": "A Long Term Follow up Study of Patients Who Have Completed the PEP005-020 Study", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Actinic Keratosis" ], "interventions": [ { "name": "Lesion count", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Peplin", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 98, "start_date": "2009-07", "completion_date": "2010-10", "has_results": false, "last_update_posted_date": "2015-03-26", "last_synced_at": "2026-10-14T18:20:25.611Z", "location_count": 8, "location_summary": "Orange Park, Florida • Newnan, Georgia • Snellville, Georgia + 5 more", "locations": [ { "city": "Orange Park", "state": "Florida" }, { "city": "Newnan", "state": "Georgia" }, { "city": "Snellville", "state": "Georgia" }, { "city": "Clinton Twp", "state": "Michigan" }, { "city": "Detroit", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT00952783" }, { "nct_id": "NCT00099112", "title": "Effect of Solar-Simulated Ultraviolet Radiation on Gene Expression in Unprotected and Sunscreen-Protected Skin of Healthy Adults With Fitzpatrick Skin Type II", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Non-melanomatous Skin Cancer", "Precancerous Condition" ], "interventions": [ { "name": "microarray analysis", "type": "GENETIC" }, { "name": "biopsy", "type": "PROCEDURE" }, { "name": "evaluation of cancer risk factors", "type": "PROCEDURE" } ], "intervention_types": [ "GENETIC", "PROCEDURE" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": null, "start_date": "2004-02", "completion_date": null, "has_results": false, "last_update_posted_date": "2015-04-30", "last_synced_at": "2026-10-14T18:20:25.611Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00099112" }, { "nct_id": "NCT03210740", "title": "Safety and Efficacy Study of AM001 Cream in the Treatment of Actinic Keratosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Actinic Keratosis" ], "interventions": [ { "name": "AM001 Cream, 7.5%", "type": "DRUG" }, { "name": "Vehicle Cream", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AmDerma", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 30, "start_date": "2017-06-06", "completion_date": "2018-04-24", "has_results": false, "last_update_posted_date": "2019-04-30", "last_synced_at": "2026-10-14T18:20:25.611Z", "location_count": 1, "location_summary": "High Point, North Carolina", "locations": [ { "city": "High Point", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03210740" }, { "nct_id": "NCT01922050", "title": "A Study of Increasing Strengths, Safety and Efficacy of Two Formulas of LEO 43204 on the Face or the Chest in Patients With Actinic Keratosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Actinic Keratosis" ], "interventions": [ { "name": "LEO 43204 Formulation 1", "type": "DRUG" }, { "name": "LEO 43204 Formulation 2", "type": "DRUG" }, { "name": "LEO 43204 Formulation 1 Dose X", "type": "DRUG" }, { "name": "LEO 43204 Formulation 1 Dose Y", "type": "DRUG" }, { "name": "LEO 43204 Formulation 2 Dose XX", "type": "DRUG" }, { "name": "LEO 43204 Formulation 2 Dose YY", "type": "DRUG" }, { "name": "Placebo Formulation 1", "type": "DRUG" }, { "name": "Placebo Formulation 2", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "LEO Pharma", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 320, "start_date": "2013-10", "completion_date": "2014-11", "has_results": true, "last_update_posted_date": "2025-03-06", "last_synced_at": "2026-10-14T18:20:25.611Z", "location_count": 13, "location_summary": "Phoenix, Arizona • Lomita, California • San Diego, California + 9 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Lomita", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Ormond Beach", "state": "Florida" }, { "city": "Tampa", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01922050" } ] }