{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Actinic+Keratosis+%28AK%29&page=2",
    "query": {
      "condition": "Actinic Keratosis (AK)",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Actinic+Keratosis+%28AK%29&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-25T14:48:39.245Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07144852",
      "title": "Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Upper Extremities",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Actinic Keratosis"
      ],
      "interventions": [
        {
          "name": "Reformulated Levulan Kerastick containing aminolevulinic acid hydrochloride (ALA HCl), 20%",
          "type": "DRUG"
        },
        {
          "name": "Vehicle",
          "type": "OTHER"
        },
        {
          "name": "Blue Light Photodynamic Therapy Illuminator device, BLU-U® model 4170E.",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Sun Pharmaceutical Industries, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 260,
      "start_date": "2025-11-29",
      "completion_date": "2027-04",
      "has_results": false,
      "last_update_posted_date": "2026-04-22",
      "last_synced_at": "2026-06-25T14:48:39.245Z",
      "location_count": 20,
      "location_summary": "Phoenix, Arizona • Fremont, California • Castle Rock, Colorado + 17 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Fremont",
          "state": "California"
        },
        {
          "city": "Castle Rock",
          "state": "Colorado"
        },
        {
          "city": "Aventura",
          "state": "Florida"
        },
        {
          "city": "North Miami Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07144852"
    },
    {
      "nct_id": "NCT01458587",
      "title": "Levulan PDT Versus Vehicle for Extremity Actinic Keratoses (AK)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Keratosis, Actinic"
      ],
      "interventions": [
        {
          "name": "Aminolevulinic Acid PDT (ALA)",
          "type": "DRUG"
        },
        {
          "name": "Vehicle PDT (VEH)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "DUSA Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2011-11",
      "completion_date": "2012-07",
      "has_results": true,
      "last_update_posted_date": "2013-03-14",
      "last_synced_at": "2026-06-25T14:48:39.245Z",
      "location_count": 3,
      "location_summary": "San Diego, California • Orange Park, Florida • Austin, Texas",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Orange Park",
          "state": "Florida"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01458587"
    },
    {
      "nct_id": "NCT02124733",
      "title": "Protocols for Painless Photodynamic Therapy (PDT) of Actinic Keratoses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Actinic Keratosis"
      ],
      "interventions": [
        {
          "name": "Aminolevulinic acid based photodynamic therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 23,
      "start_date": "2014-04",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2023-10-10",
      "last_synced_at": "2026-06-25T14:48:39.245Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02124733"
    },
    {
      "nct_id": "NCT03285477",
      "title": "A Multi-Center Study to Evaluate the Efficacy and Safety of KX2-391 Ointment 1% on AK on Face or Scalp",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Actinic Keratoses"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "KX2-391 Ointment 1%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Almirall, S.A.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 351,
      "start_date": "2017-09-18",
      "completion_date": "2019-04-24",
      "has_results": true,
      "last_update_posted_date": "2021-04-13",
      "last_synced_at": "2026-06-25T14:48:39.245Z",
      "location_count": 30,
      "location_summary": "Mobile, Alabama • Glendale, Arizona • Fremont, California + 27 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Fremont",
          "state": "California"
        },
        {
          "city": "Rancho Mirage",
          "state": "California"
        },
        {
          "city": "Wheat Ridge",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03285477"
    },
    {
      "nct_id": "NCT03727074",
      "title": "Bioequivalence Study to Compare Sol-Gel Technologies' 5-FU Cream With Efudex® (5-FU) Cream",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Actinic Keratosis (AK)"
      ],
      "interventions": [
        {
          "name": "5-FU Cream",
          "type": "DRUG"
        },
        {
          "name": "Efudex®",
          "type": "DRUG"
        },
        {
          "name": "Vehicle",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sol-Gel Technologies, Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 462,
      "start_date": "2018-12-21",
      "completion_date": "2019-12-19",
      "has_results": false,
      "last_update_posted_date": "2020-03-18",
      "last_synced_at": "2026-06-25T14:48:39.245Z",
      "location_count": 1,
      "location_summary": "Cerritos, California",
      "locations": [
        {
          "city": "Cerritos",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03727074"
    },
    {
      "nct_id": "NCT00814528",
      "title": "Photodynamic Therapy Mediated by Topical Application of 5- ALA for the Treatment of Actinic Keratoses",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Actinic Keratosis"
      ],
      "interventions": [
        {
          "name": "5-ALA plus Blu-Light",
          "type": "DRUG"
        },
        {
          "name": "5-FU, Imiquimod or treatment with cryotherapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "18 Years to 95 Years"
      },
      "enrollment_count": 0,
      "start_date": "2007-11",
      "completion_date": "2009-09",
      "has_results": false,
      "last_update_posted_date": "2018-09-10",
      "last_synced_at": "2026-06-25T14:48:39.245Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00814528"
    },
    {
      "nct_id": "NCT03110159",
      "title": "DUSA: Cyclic PDT for the Prevention of AK & NMSC in Solid Organ Transplant Recipients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Skin Cancer",
        "Non-melanoma Skin Cancer",
        "Sun Damaged Skin",
        "Actinic Keratosis"
      ],
      "interventions": [
        {
          "name": "Levulan® Kerastick®",
          "type": "DRUG"
        },
        {
          "name": "BLU-U Blue Light Photodynamic Therapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medical Dermatology Specialists",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2017-08-29",
      "completion_date": "2024-02-20",
      "has_results": false,
      "last_update_posted_date": "2024-03-15",
      "last_synced_at": "2026-06-25T14:48:39.245Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03110159"
    },
    {
      "nct_id": "NCT03210740",
      "title": "Safety and Efficacy Study of AM001 Cream in the Treatment of Actinic Keratosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Actinic Keratosis"
      ],
      "interventions": [
        {
          "name": "AM001 Cream, 7.5%",
          "type": "DRUG"
        },
        {
          "name": "Vehicle Cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "AmDerma",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2017-06-06",
      "completion_date": "2018-04-24",
      "has_results": false,
      "last_update_posted_date": "2019-04-30",
      "last_synced_at": "2026-06-25T14:48:39.245Z",
      "location_count": 1,
      "location_summary": "High Point, North Carolina",
      "locations": [
        {
          "city": "High Point",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03210740"
    },
    {
      "nct_id": "NCT01516515",
      "title": "Efficacy and Safety Phase II Study of SR-T100 to Treat Actinic Keratosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Actinic Keratosis"
      ],
      "interventions": [
        {
          "name": "Vehicle gel",
          "type": "DRUG"
        },
        {
          "name": "SR-T100 with 2.3% of SM",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "G&E Herbal Biotechnology Co., LTD",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 86,
      "start_date": "2013-02",
      "completion_date": "2018-10",
      "has_results": false,
      "last_update_posted_date": "2018-12-05",
      "last_synced_at": "2026-06-25T14:48:39.245Z",
      "location_count": 8,
      "location_summary": "Rancho Mirage, California • Longmont, Colorado • West Palm Beach, Florida + 4 more",
      "locations": [
        {
          "city": "Rancho Mirage",
          "state": "California"
        },
        {
          "city": "Longmont",
          "state": "Colorado"
        },
        {
          "city": "West Palm Beach",
          "state": "Florida"
        },
        {
          "city": "West Palm Beach",
          "state": "Florida"
        },
        {
          "city": "Katy",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01516515"
    },
    {
      "nct_id": "NCT07144345",
      "title": "Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Face and Scalp",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Actinic Keratosis"
      ],
      "interventions": [
        {
          "name": "Reformulated Levulan Kerastick containing aminolevulinic acid hydrochloride (ALA HCl), 20%",
          "type": "DRUG"
        },
        {
          "name": "Vehicle containing excipients only (VEH) without active ingredient",
          "type": "OTHER"
        },
        {
          "name": "Blue Light Photodynamic Therapy Illuminator device, BLU-U® model 4170E",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Sun Pharmaceutical Industries, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 160,
      "start_date": "2025-11-19",
      "completion_date": "2027-04",
      "has_results": false,
      "last_update_posted_date": "2026-04-22",
      "last_synced_at": "2026-06-25T14:48:39.245Z",
      "location_count": 10,
      "location_summary": "Fremont, California • Aventura, Florida • Rolling Meadows, Illinois + 7 more",
      "locations": [
        {
          "city": "Fremont",
          "state": "California"
        },
        {
          "city": "Aventura",
          "state": "Florida"
        },
        {
          "city": "Rolling Meadows",
          "state": "Illinois"
        },
        {
          "city": "Plainfield",
          "state": "Indiana"
        },
        {
          "city": "New Brighton",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07144345"
    }
  ]
}