{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Acute+Hypoxic+Respiratory+Failure",
    "query": {
      "condition": "Acute Hypoxic Respiratory Failure"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 15,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Acute+Hypoxic+Respiratory+Failure&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T07:18:34.520Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03969615",
      "title": "SuperNO2VA™ and General Anesthesia Postoperative Care",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypoxemia",
        "Acute Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "SuperNO2VA nasal positive airway pressure devic",
          "type": "DEVICE"
        },
        {
          "name": "Supplemental oxygen",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vyaire Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2018-10-15",
      "completion_date": "2019-10-15",
      "has_results": false,
      "last_update_posted_date": "2019-06-03",
      "last_synced_at": "2026-06-26T07:18:34.520Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03969615"
    },
    {
      "nct_id": "NCT04408222",
      "title": "Awake Proning in COVID-19 Patients With Hypoxemic Respiratory Failure",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Oxygen Deficiency",
        "Coronavirus Infection"
      ],
      "interventions": [
        {
          "name": "Awake proning",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2020-04-16",
      "completion_date": "2022-03-06",
      "has_results": false,
      "last_update_posted_date": "2022-03-09",
      "last_synced_at": "2026-06-26T07:18:34.520Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04408222"
    },
    {
      "nct_id": "NCT00041561",
      "title": "Effects of Inhaled Nitric Oxide in the Treatment of Acute Hypoxemic Respiratory Failure (AHRF) in Pediatrics",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Respiratory Insufficiency",
        "Anoxemia"
      ],
      "interventions": [
        {
          "name": "Nitrogen gas",
          "type": "DRUG"
        },
        {
          "name": "inhaled nitric oxide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mallinckrodt",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "Up to 16 Years"
      },
      "enrollment_count": 55,
      "start_date": "2002-01",
      "completion_date": "2004-12",
      "has_results": false,
      "last_update_posted_date": "2016-07-26",
      "last_synced_at": "2026-06-26T07:18:34.520Z",
      "location_count": 16,
      "location_summary": "Orange, California • Stanford, California • Denver, Colorado + 13 more",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00041561"
    },
    {
      "nct_id": "NCT04681040",
      "title": "Risk Stratification of COVID-19 Using Urine Biomarkers",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Covid19",
        "Urine",
        "Biomarker",
        "Acute Respiratory Failure With Hypoxia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Center for Global Health and Medicine, Japan",
      "sponsor_class": "OTHER_GOV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "20 Years and older"
      },
      "enrollment_count": 964,
      "start_date": "2020-09-15",
      "completion_date": "2024-03-25",
      "has_results": false,
      "last_update_posted_date": "2024-03-27",
      "last_synced_at": "2026-06-26T07:18:34.520Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04681040"
    },
    {
      "nct_id": "NCT04193878",
      "title": "ARrest RESpiraTory Failure From PNEUMONIA",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pneumonia",
        "Hypoxemia",
        "Acute Respiratory Failure",
        "COVID-19 Pneumonia"
      ],
      "interventions": [
        {
          "name": "Inhaled budesonide and formoterol",
          "type": "DRUG"
        },
        {
          "name": "Inhaled placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 465,
      "start_date": "2020-06-01",
      "completion_date": "2025-07-22",
      "has_results": false,
      "last_update_posted_date": "2025-08-19",
      "last_synced_at": "2026-06-26T07:18:34.520Z",
      "location_count": 12,
      "location_summary": "Birmingham, Alabama • Scottsdale, Arizona • Tucson, Arizona + 8 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04193878"
    },
    {
      "nct_id": "NCT01937884",
      "title": "Supplemental Parenteral Nutrition in Pediatric Respiratory Failure",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Respiratory Failure With Hypoxia",
        "Malnutrition"
      ],
      "interventions": [
        {
          "name": "Parenteral Nutrition",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Arizona",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "1 Month to 16 Years"
      },
      "enrollment_count": 18,
      "start_date": "2013-08",
      "completion_date": "2018-08",
      "has_results": true,
      "last_update_posted_date": "2021-03-03",
      "last_synced_at": "2026-06-26T07:18:34.520Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01937884"
    },
    {
      "nct_id": "NCT02114944",
      "title": "Treatment of Dyspnea in Do-not-intubate Patients",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Respiratory Failure",
        "Acute on Chronic Respiratory Failure",
        "Dyspnea"
      ],
      "interventions": [
        {
          "name": "NIV",
          "type": "DEVICE"
        },
        {
          "name": "CPAP",
          "type": "DEVICE"
        },
        {
          "name": "Standard oxygen",
          "type": "DEVICE"
        },
        {
          "name": "HFNC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2014-04",
      "completion_date": "2023-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-05-13",
      "last_synced_at": "2026-06-26T07:18:34.520Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02114944"
    },
    {
      "nct_id": "NCT02105298",
      "title": "Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Respiratory Failure",
        "Acute Respiratory Failure Requiring Reintubation",
        "Pulmonary Edema",
        "Pneumonia",
        "Hypoxia",
        "Acute Kidney Injury"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 104000,
      "start_date": "2013-09",
      "completion_date": "2014-03",
      "has_results": false,
      "last_update_posted_date": "2015-08-21",
      "last_synced_at": "2026-06-26T07:18:34.520Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02105298"
    },
    {
      "nct_id": "NCT03021824",
      "title": "Severe ARDS: Generating Evidence",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Respiratory Distress Syndrome",
        "Acute Respiratory Failure With Hypoxia",
        "Acute Respiratory Failure"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2400,
      "start_date": "2016-10-01",
      "completion_date": "2017-04-30",
      "has_results": false,
      "last_update_posted_date": "2020-01-28",
      "last_synced_at": "2026-06-26T07:18:34.520Z",
      "location_count": 28,
      "location_summary": "Tucson, Arizona • Los Angeles, California • Jacksonville, Florida + 22 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03021824"
    },
    {
      "nct_id": "NCT04079829",
      "title": "Postoperative Respiratory Abnormalities",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Respiratory Failure",
        "Respiratory Arrest",
        "Respiratory Distress Syndrome",
        "Acute Respiratory Failure",
        "Acute Respiratory Failure With Hypoxia",
        "Acute Respiratory Failure With Hypercapnia",
        "Acute Respiratory Failure Post Surgical",
        "Acute Respiratory Failure Postprocedural",
        "Acute Respiratory Failure Following Trauma and Surgery",
        "Acute Respiratory Failure Requiring Reintubation",
        "Acute Respiratory Failure Post Traumatic",
        "Acute Respiratory Decompensation",
        "Shock",
        "Shock, Septic",
        "Shock, Cardiogenic",
        "Acute Cardiac Failure",
        "Multi Organ Failure",
        "Acute Kidney Failure"
      ],
      "interventions": [
        {
          "name": "Observational retrospective cohort to describe data validity; and Data reliability; and Completeness of the data",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Efficacy Care R&D Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 50000,
      "start_date": "2019-09-01",
      "completion_date": "2020-10",
      "has_results": false,
      "last_update_posted_date": "2020-06-24",
      "last_synced_at": "2026-06-26T07:18:34.520Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04079829"
    }
  ]
}