{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Acute+Injury+of+Anterior+Cruciate+Ligament",
    "query": {
      "condition": "Acute Injury of Anterior Cruciate Ligament"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T06:07:13.507Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01773317",
      "title": "Can Neuromuscular Training Alter Movement Patterns",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Injury of Anterior Cruciate Ligament"
      ],
      "interventions": [
        {
          "name": "Perturbation",
          "type": "OTHER"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Lynn Snyder-Mackler",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "13 Years to 55 Years"
      },
      "enrollment_count": 80,
      "start_date": "2011-11",
      "completion_date": "2018-08-28",
      "has_results": false,
      "last_update_posted_date": "2019-07-25",
      "last_synced_at": "2026-07-24T06:07:13.507Z",
      "location_count": 1,
      "location_summary": "Newark, Delaware",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01773317"
    },
    {
      "nct_id": "NCT02930122",
      "title": "IL-1RA Treatment in Patients With Acute ACL Tear and Painful Effusions",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Tear"
      ],
      "interventions": [
        {
          "name": "anakinra (150mg)",
          "type": "DRUG"
        },
        {
          "name": "Saline intraarticularly",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Cale Jacobs, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "14 Years to 40 Years"
      },
      "enrollment_count": 6,
      "start_date": "2019-06-20",
      "completion_date": "2020-10-16",
      "has_results": true,
      "last_update_posted_date": "2021-11-24",
      "last_synced_at": "2026-07-24T06:07:13.507Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02930122"
    },
    {
      "nct_id": "NCT04593264",
      "title": "Quantifying the Benefits of Supervised vs. Unsupervised Pre-habilitation for Patients With Acute ACL Tears",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Rupture",
        "Anterior Cruciate Ligament Tear",
        "Anterior Cruciate Ligament Injuries"
      ],
      "interventions": [
        {
          "name": "Self-guided pre-habilitation exercise program",
          "type": "OTHER"
        },
        {
          "name": "Traditional pre-habilitation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "WellSpan Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "13 Years to 50 Years"
      },
      "enrollment_count": 128,
      "start_date": "2021-02-23",
      "completion_date": "2022-06-30",
      "has_results": false,
      "last_update_posted_date": "2023-03-27",
      "last_synced_at": "2026-07-24T06:07:13.507Z",
      "location_count": 1,
      "location_summary": "York, Pennsylvania",
      "locations": [
        {
          "city": "York",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04593264"
    },
    {
      "nct_id": "NCT02010125",
      "title": "Feasibility Trial Using Imaging and Biochemical Technologies to Measure Knee Cartilage Composition in Acute ACL Injury",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Injury of Anterior Cruciate Ligament"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "13 Years to 70 Years"
      },
      "enrollment_count": 89,
      "start_date": "2013-11",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2018-11-13",
      "last_synced_at": "2026-07-24T06:07:13.507Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02010125"
    },
    {
      "nct_id": "NCT07142369",
      "title": "Synovial Fluid Withdrawal or PRP Injection For Acute ACL Tears and Cytokines",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Posttraumatic Osteoarthritis",
        "Anterior Cruciate Ligament (ACL) Rupture"
      ],
      "interventions": [
        {
          "name": "Synovial Fluid withdrawal at the preoperative clinic visit",
          "type": "PROCEDURE"
        },
        {
          "name": "Platelet-Rich Plasma (PRP) preparation and injection",
          "type": "PROCEDURE"
        },
        {
          "name": "Synovial fluid withdrawal at the time of surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "3mL synovial fluid withdrawn at the preoperative visit",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 99,
      "start_date": "2026-09",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-18",
      "last_synced_at": "2026-07-24T06:07:13.507Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07142369"
    },
    {
      "nct_id": "NCT00332254",
      "title": "Study to Prevent Cartilage Damage Following Acute Knee Injury.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Knee Injury"
      ],
      "interventions": [
        {
          "name": "Anakinra",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 10,
      "start_date": "2006-03",
      "completion_date": "2007-06",
      "has_results": false,
      "last_update_posted_date": "2013-05-30",
      "last_synced_at": "2026-07-24T06:07:13.507Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00332254"
    },
    {
      "nct_id": "NCT04088227",
      "title": "Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Tear",
        "Anterior Cruciate Ligament Rupture"
      ],
      "interventions": [
        {
          "name": "Experimental Group",
          "type": "DRUG"
        },
        {
          "name": "Control Group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Andrews Research & Education Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "14 Years to 40 Years"
      },
      "enrollment_count": 24,
      "start_date": "2019-09-12",
      "completion_date": "2023-04-21",
      "has_results": true,
      "last_update_posted_date": "2025-02-17",
      "last_synced_at": "2026-07-24T06:07:13.507Z",
      "location_count": 1,
      "location_summary": "Gulf Breeze, Florida",
      "locations": [
        {
          "city": "Gulf Breeze",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04088227"
    },
    {
      "nct_id": "NCT00504114",
      "title": "MR Imaging of Knee Osteoarthritis and Acute Knee Injuries",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthritis, Knee"
      ],
      "interventions": [
        {
          "name": "ACL Reconstruction Surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Cartilage Resurfacing Surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Total Knee Replacement",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 139,
      "start_date": "2006-08",
      "completion_date": "2013-07",
      "has_results": false,
      "last_update_posted_date": "2013-12-12",
      "last_synced_at": "2026-07-24T06:07:13.507Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00504114"
    },
    {
      "nct_id": "NCT06529679",
      "title": "Michigan Split-belt Treadmill Training Program to Improve Acute Knee Biomechanics After ACL Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL",
        "ACL Injury"
      ],
      "interventions": [
        {
          "name": "Split-belt Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tied-Belt Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "14 Years to 45 Years"
      },
      "enrollment_count": 32,
      "start_date": "2024-10-29",
      "completion_date": "2026-02-25",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-07-24T06:07:13.507Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06529679"
    }
  ]
}