{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Acute+Orthopedic+Injury",
    "query": {
      "condition": "Acute Orthopedic Injury"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 14,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Acute+Orthopedic+Injury&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T15:36:10.813Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00685295",
      "title": "Fentanyl Administered Intraorally for Rapid Treatment of Orthopedic Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Pain, Fracture, Sprain"
      ],
      "interventions": [
        {
          "name": "Fentanyl",
          "type": "DRUG"
        },
        {
          "name": "Lansoprazole",
          "type": "DRUG"
        },
        {
          "name": "Oxycodone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 60,
      "start_date": "2008-08",
      "completion_date": "2009-02",
      "has_results": true,
      "last_update_posted_date": "2017-02-09",
      "last_synced_at": "2026-07-22T15:36:10.813Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00685295"
    },
    {
      "nct_id": "NCT06624969",
      "title": "Virtual Reality in Reducing Acute Orthopedic Pain",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fractures"
      ],
      "interventions": [
        {
          "name": "virtual reality",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2026-04-23",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-07-22T15:36:10.813Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06624969"
    },
    {
      "nct_id": "NCT05552430",
      "title": "Virtual Reality for Pain in Acute Orthopedic Injuries",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Injuries",
        "Injury Arm",
        "Injury;Sports",
        "Injury, Knee",
        "Injury Wrist",
        "Injury, Ankle",
        "Injury Foot",
        "Injury, Hand",
        "Injury Finger",
        "Injury Leg"
      ],
      "interventions": [
        {
          "name": "RelieveVRx",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2022-10-17",
      "completion_date": "2023-10-12",
      "has_results": true,
      "last_update_posted_date": "2024-08-22",
      "last_synced_at": "2026-07-22T15:36:10.813Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05552430"
    },
    {
      "nct_id": "NCT05292001",
      "title": "Single-dose Intravenous Iron Therapy for Anemia After Orthopaedic Trauma",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Acute Blood Loss Anemia",
        "Fracture"
      ],
      "interventions": [
        {
          "name": "Iron-Dextran Complex Injection [InFed]",
          "type": "DRUG"
        },
        {
          "name": "Saline Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 150,
      "start_date": "2022-06-01",
      "completion_date": "2026-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-08-08",
      "last_synced_at": "2026-07-22T15:36:10.813Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05292001"
    },
    {
      "nct_id": "NCT03991546",
      "title": "Pain and Narcotic Usage After Orthopaedic Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fractures, Closed",
        "Pain, Postoperative",
        "Pain Catastrophizing",
        "Pain, Acute",
        "Analgesia",
        "Opioid Use",
        "Acceptance and Commitment Therapy",
        "Orthopedics",
        "Analgesics, Opioid",
        "Text Messaging"
      ],
      "interventions": [
        {
          "name": "Acceptance and Commitment Therapy Delivered via an Automated Mobile Messaging Robot",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Christopher Anthony",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 82,
      "start_date": "2016-06-03",
      "completion_date": "2019-06-17",
      "has_results": false,
      "last_update_posted_date": "2019-09-04",
      "last_synced_at": "2026-07-22T15:36:10.813Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03991546"
    },
    {
      "nct_id": "NCT04973696",
      "title": "Toolkit for Optimal Recovery After Orthopedic Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Orthopedic Injury"
      ],
      "interventions": [
        {
          "name": "Toolkit for Optimal Recovery after Orthopedic Injury",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Minimally Enhanced Usual Care (MEUC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 195,
      "start_date": "2021-09-21",
      "completion_date": "2023-08-15",
      "has_results": true,
      "last_update_posted_date": "2025-06-27",
      "last_synced_at": "2026-07-22T15:36:10.813Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04973696"
    },
    {
      "nct_id": "NCT00411060",
      "title": "Clinical Orthopaedic Data Bank (Acute and Chronic)",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthritis",
        "Osteosarcoma",
        "Scoliosis",
        "Cerebral Palsy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 10000,
      "start_date": "2007-01",
      "completion_date": "2026-08-14",
      "has_results": false,
      "last_update_posted_date": "2025-08-06",
      "last_synced_at": "2026-07-22T15:36:10.813Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00411060"
    },
    {
      "nct_id": "NCT06201676",
      "title": "Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Orthopaedic Trauma",
        "Chronic Opioid Use"
      ],
      "interventions": [
        {
          "name": "Ketorolac Injection",
          "type": "DRUG"
        },
        {
          "name": "Standard of Care (SOC) Multimodal Analgesia",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 458,
      "start_date": "2025-02-28",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-07-22T15:36:10.813Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Nashville, Tennessee",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06201676"
    },
    {
      "nct_id": "NCT03532256",
      "title": "Post-op Crowd Sourcing Health Data Via Text-messaging",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Orthopedic Surgery",
        "Opioid Use",
        "Acute Injuries Knee",
        "Neurosurgery",
        "Surgery"
      ],
      "interventions": [
        {
          "name": "Observation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Text to online survey",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Bi-directional text script",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 127,
      "start_date": "2019-07-01",
      "completion_date": "2019-09-16",
      "has_results": true,
      "last_update_posted_date": "2025-06-04",
      "last_synced_at": "2026-07-22T15:36:10.813Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03532256"
    },
    {
      "nct_id": "NCT02301832",
      "title": "Reliability of Sensor Spacing for NIRS in Traumatic Tibia Fractures",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Orthopedic Disorders",
        "Tibial Fractures"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 14,
      "start_date": "2014-12",
      "completion_date": "2016-07-20",
      "has_results": false,
      "last_update_posted_date": "2017-02-06",
      "last_synced_at": "2026-07-22T15:36:10.813Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02301832"
    }
  ]
}