{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Acute+Respiratory+Insufficiency&page=9", "query": { "condition": "Acute Respiratory Insufficiency", "page": 9 }, "page_size": 10 }, "pagination": { "page": 9, "page_size": 10, "total_count": 214, "total_pages": 22, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Acute+Respiratory+Insufficiency&page=10&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Acute+Respiratory+Insufficiency&page=8&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-11T04:27:10.370Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04141891", "title": "Advancing Understanding of Transportation Options", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Diabetic Retinopathy", "Macular Degeneration", "Glaucoma", "Retinitis Pigmentosa", "Vision Disorders", "Acute Coronary Syndrome", "Implantable Defibrillator User", "Congestive Heart Failure", "Hypertrophic Obstructive Cardiomyopathy", "Orthostatic Hypotension", "Syncope", "Presyncope", "Narcolepsy", "Dementia", "Multiple Sclerosis", "Parkinson Disease", "Brain Injuries", "Spinal Cord Injuries", "Stroke", "Vertigo", "Dizziness", "Seizures", "Substance Use", "Insulin Dependent Diabetes Mellitus", "Arthritis", "Foot--Abnormalities", "Chronic Obstructive Pulmonary Disease", "Obstructive Sleep Apnea", "End Stage Renal Disease", "Sleep Apnea", "Insomnia", "Restless Legs Syndrome" ], "interventions": [ { "name": "Driving Decision Aid", "type": "BEHAVIORAL" }, { "name": "Older Drivers Website", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 529, "start_date": "2019-12-12", "completion_date": "2023-12-21", "has_results": true, "last_update_posted_date": "2025-02-21", "last_synced_at": "2026-10-11T04:27:10.370Z", "location_count": 3, "location_summary": "La Jolla, California • Aurora, Colorado • Indianapolis, Indiana", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT04141891" }, { "nct_id": "NCT07293078", "title": "Point-of-Care AI Assistance and Critical Care Outcomes: A Randomized Trial", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Critical Illness", "Sepsis", "Acute Respiratory Failure (ARF)", "Multi-organ Failure", "Acute Kidney Injury", "Delirium Confusional State", "Shock" ], "interventions": [ { "name": "Point-of-care large language model decision support (ChatGPT-5)", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "MetroWest Artificial Intelligence Research Workgroup", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1000, "start_date": "2026-01-01", "completion_date": "2029-06-30", "has_results": false, "last_update_posted_date": "2025-12-18", "last_synced_at": "2026-10-11T04:27:10.370Z", "location_count": 1, "location_summary": "Framingham, Massachusetts", "locations": [ { "city": "Framingham", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT07293078" }, { "nct_id": "NCT04482712", "title": "Effects of mTOR Inhibition With Sirolimus (RAPA) in Patients With COVID-19 to Moderate the Progression of ARDS", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)", "Respiratory Failure", "Sars-CoV2" ], "interventions": [ { "name": "Rapamycin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The University of Texas Health Science Center at San Antonio", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": null, "sex": "ALL", "summary": "60 Years and older" }, "enrollment_count": 0, "start_date": "2021-04", "completion_date": "2023-01", "has_results": false, "last_update_posted_date": "2021-06-01", "last_synced_at": "2026-10-11T04:27:10.370Z", "location_count": 2, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04482712" }, { "nct_id": "NCT02841592", "title": "Non-rebreather at Flush Rate Compared to Bag Valve Mask With Assist", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Acute Respiratory Failure" ], "interventions": [ { "name": "Flush rate oxygen", "type": "OTHER" }, { "name": "Flush rate oxygen with assist", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Hennepin Healthcare Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 27, "start_date": "2016-07", "completion_date": "2016-08", "has_results": false, "last_update_posted_date": "2018-01-30", "last_synced_at": "2026-10-11T04:27:10.370Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT02841592" }, { "nct_id": "NCT05295784", "title": "PK and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Acute Kidney Injury", "Hypoxic-Ischemic Encephalopathy", "Caffeine" ], "interventions": [ { "name": "Caffeine citrate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Arkansas", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "0 Hours", "maximum_age": "24 Hours", "sex": "ALL", "summary": "0 Hours to 24 Hours" }, "enrollment_count": 0, "start_date": "2024-05-08", "completion_date": "2024-05-08", "has_results": false, "last_update_posted_date": "2024-05-10", "last_synced_at": "2026-10-11T04:27:10.370Z", "location_count": 2, "location_summary": "Little Rock, Arkansas", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Little Rock", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05295784" }, { "nct_id": "NCT00976833", "title": "Standardized Rehabilitation for Intensive Care Unit (ICU) Patients With Acute Respiratory Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Acute Respiratory Failure" ], "interventions": [ { "name": "Standardized Rehabilitation", "type": "OTHER" }, { "name": "Usual Care", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Wake Forest University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 300, "start_date": "2009-10", "completion_date": "2015-06", "has_results": false, "last_update_posted_date": "2018-08-10", "last_synced_at": "2026-10-11T04:27:10.370Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00976833" }, { "nct_id": "NCT04401423", "title": "TXA127 for the Treatment of Severe COVID-19", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "COVID-19" ], "interventions": [ { "name": "TXA127", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 22, "start_date": "2021-02-10", "completion_date": "2021-06-10", "has_results": true, "last_update_posted_date": "2022-07-27", "last_synced_at": "2026-10-11T04:27:10.370Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04401423" }, { "nct_id": "NCT03456323", "title": "Post-ICU Palliative Care Intervention (PIPCI) Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Critical Illness", "Frailty", "Palliative Care" ], "interventions": [ { "name": "Palliative Care Consultation", "type": "BEHAVIORAL" }, { "name": "Usual Care", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "OTHER" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 66, "start_date": "2018-03-20", "completion_date": "2019-01-23", "has_results": false, "last_update_posted_date": "2024-07-16", "last_synced_at": "2026-10-11T04:27:10.370Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT03456323" }, { "nct_id": "NCT07845305", "title": "INtubation With Sedation Only to Preserve Independent Respiratory Effort Trial", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Acute Respiratory Failure" ], "interventions": [ { "name": "Intubation with a sedative medication only", "type": "OTHER" }, { "name": "Intubation with a sedative medication and neuromuscular blockade agent", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 228, "start_date": "2026-09-28", "completion_date": "2030-05-29", "has_results": false, "last_update_posted_date": "2026-09-30", "last_synced_at": "2026-10-11T04:27:10.370Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT07845305" }, { "nct_id": "NCT02014285", "title": "Muscle Ultrasound Signifies Condition Upgrade Leading Approach to Recovery", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Acute Respiratory Failure", "Critical Illness" ], "interventions": [ { "name": "Muscle Ultrasound and Muscle Sample", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Wake Forest University Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1, "start_date": "2012-11", "completion_date": "2017-05-03", "has_results": false, "last_update_posted_date": "2017-11-08", "last_synced_at": "2026-10-11T04:27:10.370Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02014285" } ] }