{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Adenomatous+Polyposis&page=2", "query": { "condition": "Adenomatous Polyposis", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Adenomatous+Polyposis&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-06-25T17:23:51.385Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03847636", "title": "CryoBalloon Ablation for Treatment of Duodenal Adenomas", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Duodenal Adenomas", "Familial Adenomatous Polyposis" ], "interventions": [ { "name": "CryoBalloon ablation", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Johns Hopkins University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 44, "start_date": "2019-05-13", "completion_date": "2026-03", "has_results": false, "last_update_posted_date": "2025-03-11", "last_synced_at": "2026-06-25T17:23:51.385Z", "location_count": 4, "location_summary": "Baltimore, Maryland • Manhasset, New York • Danville, Pennsylvania + 1 more", "locations": [ { "city": "Baltimore", "state": "Maryland" }, { "city": "Manhasset", "state": "New York" }, { "city": "Danville", "state": "Pennsylvania" }, { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03847636" }, { "nct_id": "NCT05630794", "title": "Testing for Safety and Colorectal Cancer Preventive Effects of ONC201", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Colorectal Adenomatous Polyp", "Colorectal Carcinoma", "Familial Adenomatous Polyposis", "Multiple Adenomatous Polyps" ], "interventions": [ { "name": "Biopsy Procedure", "type": "PROCEDURE" }, { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Colonoscopy", "type": "PROCEDURE" }, { "name": "Dordaviprone Hydrochloride", "type": "DRUG" }, { "name": "Questionnaire Administration", "type": "OTHER" }, { "name": "Sigmoidoscopy", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE", "DRUG", "OTHER" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 36, "start_date": "2025-10-06", "completion_date": "2028-03-01", "has_results": false, "last_update_posted_date": "2026-06-12", "last_synced_at": "2026-06-25T17:23:51.385Z", "location_count": 5, "location_summary": "Ann Arbor, Michigan • St Louis, Missouri • Cleveland, Ohio + 2 more", "locations": [ { "city": "Ann Arbor", "state": "Michigan" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Cleveland", "state": "Ohio" }, { "city": "Columbus", "state": "Ohio" }, { "city": "Providence", "state": "Rhode Island" } ], "official_url": "https://clinicaltrials.gov/study/NCT05630794" }, { "nct_id": "NCT00663819", "title": "Bioabsorbable Staple Line Reinforcement in Colorectal,Coloanal and Ileoanal Anastomoses", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Rectal Cancer", "Ulcerative Colitis", "Familial Adenomatous Polyposis", "Diverticulitis" ], "interventions": [ { "name": "GORE SEAMGUARD® Bioabsorbable Staple Line Reinforcement", "type": "DEVICE" }, { "name": "Staple line without reinforcement", "type": "PROCEDURE" } ], "intervention_types": [ "DEVICE", "PROCEDURE" ], "sponsor": "W.L.Gore & Associates", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 258, "start_date": "2008-04", "completion_date": "2012-10", "has_results": true, "last_update_posted_date": "2018-04-17", "last_synced_at": "2026-06-25T17:23:51.385Z", "location_count": 16, "location_summary": "Mobile, Alabama • Los Angeles, California • Weston, Florida + 12 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "Weston", "state": "Florida" }, { "city": "Barrington", "state": "Illinois" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00663819" }, { "nct_id": "NCT03027401", "title": "Clinical Sequencing of Cancer and Tissue Repository: OncoGenomics", "overall_status": "WITHDRAWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Neoplasms", "Adenomatous Polyposis Coli", "Neurofibroma, Plexiform", "Myelodysplastic Syndromes" ], "interventions": [], "intervention_types": [], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "99 Years", "sex": "ALL", "summary": "Up to 99 Years" }, "enrollment_count": 0, "start_date": "2017-01-10", "completion_date": "2020-10-05", "has_results": false, "last_update_posted_date": "2020-10-08", "last_synced_at": "2026-06-25T17:23:51.385Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03027401" }, { "nct_id": "NCT03649971", "title": "A Study of Guselkumab in Participants With Familial Adenomatous Polyposis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Adenomatous Polyposis Coli" ], "interventions": [ { "name": "Guselkumab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 77, "start_date": "2018-11-19", "completion_date": "2022-03-23", "has_results": false, "last_update_posted_date": "2025-02-03", "last_synced_at": "2026-06-25T17:23:51.385Z", "location_count": 18, "location_summary": "Phoenix, Arizona • Duarte, California • New Haven, Connecticut + 13 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Duarte", "state": "California" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03649971" }, { "nct_id": "NCT05014360", "title": "A Study of JNJ-64251330 in Participants With Familial Adenomatous Polyposis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Adenomatous Polyposis Coli" ], "interventions": [ { "name": "JNJ-64251330", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 42, "start_date": "2021-11-10", "completion_date": "2023-02-15", "has_results": false, "last_update_posted_date": "2023-06-02", "last_synced_at": "2026-06-25T17:23:51.385Z", "location_count": 5, "location_summary": "Duarte, California • Miami, Florida • Boston, Massachusetts + 1 more", "locations": [ { "city": "Duarte", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05014360" }, { "nct_id": "NCT03050268", "title": "Familial Investigations of Childhood Cancer Predisposition", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Acute Leukemia", "Adenomatous Polyposis", "Adrenocortical Carcinoma", "AML", "BAP1 Tumor Predisposition Syndrome", "Carney Complex", "Choroid Plexus Carcinoma", "Constitutional Mismatch Repair Deficiency Syndrome", "Diamond-Blackfan Anemia", "DICER1 Syndrome", "Dyskeratosis Congenita", "Emberger Syndrome", "Familial Acute Myeloid Leukemia", "Familial Adenomatous Polyposis", "Fanconi Anemia", "Familial Cancer", "Familial Wilms Tumor", "Familial Neuroblastoma", "GIST", "Hereditary Breast and Ovarian Cancer", "Hereditary Paraganglioma-Pheochromocytoma Syndrome", "Hodgkin Lymphoma", "Juvenile Polyposis", "Li-Fraumeni Syndrome", "Lynch Syndrome", "MDS", "Melanoma Syndrome", "Multiple Endocrine Neoplasia Type 1", "Multiple Endocrine Neoplasia Type 2", "Neuroblastoma", "Neurofibromatosis Type 1", "Neurofibromatosis Type II", "Nevoid Basal Cell Carcinoma Syndrome", "Non Hodgkin Lymphoma", "Noonan Syndrome and Other Rasopathy", "Overgrowth Syndromes", "Pancreatic Cancer", "Peutz-Jeghers Syndrome", "Pheochromocytoma/Paraganglioma", "PTEN Hamartoma Tumor Syndrome", "Retinoblastoma", "Rhabdoid Tumor Predisposition Syndrome", "Rhabdomyosarcoma", "Rothmund-Thomson Syndrome", "Tuberous Sclerosis", "Von Hippel-Lindau Disease" ], "interventions": [], "intervention_types": [], "sponsor": "St. Jude Children's Research Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1500, "start_date": "2017-04-06", "completion_date": "2037-03-31", "has_results": false, "last_update_posted_date": "2026-06-17", "last_synced_at": "2026-06-25T17:23:51.385Z", "location_count": 1, "location_summary": "Memphis, Tennessee", "locations": [ { "city": "Memphis", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT03050268" }, { "nct_id": "NCT04678011", "title": "A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Familial Adenomatous Polyposis" ], "interventions": [ { "name": "Personalized surveillance and intervention protocol", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1000, "start_date": "2021-11-24", "completion_date": "2026-11", "has_results": false, "last_update_posted_date": "2026-02-23", "last_synced_at": "2026-06-25T17:23:51.385Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04678011" }, { "nct_id": "NCT02747862", "title": "Non-Surgical Management of Attenuated and Deleterious (Classical) Familial Adenomatous Polyposis: A Long-term Surveillance Program", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Attenuated Familial Adenomatous Polyposis", "Deleterious Familial Adenomatous Polyposis" ], "interventions": [ { "name": "Chart Review", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1500, "start_date": "2008-02", "completion_date": "2022-08-17", "has_results": false, "last_update_posted_date": "2022-09-02", "last_synced_at": "2026-06-25T17:23:51.385Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02747862" }, { "nct_id": "NCT06578637", "title": "Investigation of β-hydroxybutyrate Supplementation as Chemoprevention in Familial Adenomatous Polyposis", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "FAP", "Familial Adenomatous Polyposis" ], "interventions": [ { "name": "R-1,3-Butanediol (10G-A)", "type": "DIETARY_SUPPLEMENT" }, { "name": "R-1,3-Butanediol (20G-A)", "type": "DIETARY_SUPPLEMENT" }, { "name": "R-1,3-Butanediol (30G-A)", "type": "DIETARY_SUPPLEMENT" }, { "name": "R-1,3-Butanediol (30G-B)", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "Abramson Cancer Center at Penn Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2024-09-20", "completion_date": "2027-10", "has_results": false, "last_update_posted_date": "2025-09-04", "last_synced_at": "2026-06-25T17:23:51.385Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT06578637" } ] }