{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Adrenergic+Beta-Receptor+Blockader",
    "query": {
      "condition": "Adrenergic Beta-Receptor Blockader"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 107,
    "total_pages": 11,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Adrenergic+Beta-Receptor+Blockader&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T18:09:55.173Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04757584",
      "title": "Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEF",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Heart Failure",
        "Heart Failure, Diastolic",
        "Heart Failure With Preserved Ejection Fraction",
        "Cardiac Failure",
        "Heart Disease"
      ],
      "interventions": [
        {
          "name": "Beta blockers",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 9,
      "start_date": "2021-04-01",
      "completion_date": "2023-04-28",
      "has_results": true,
      "last_update_posted_date": "2024-04-09",
      "last_synced_at": "2026-07-23T18:09:55.173Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04757584"
    },
    {
      "nct_id": "NCT05585125",
      "title": "A Preliminary Study for INFORMED",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Heart Failure",
        "Heart Failure, Diastolic",
        "Heart Failure With Preserved Ejection Fraction",
        "Cardiac Failure",
        "Heart Diseases"
      ],
      "interventions": [
        {
          "name": "Beta blocker",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2024-02-07",
      "completion_date": "2026-07",
      "has_results": false,
      "last_update_posted_date": "2025-10-23",
      "last_synced_at": "2026-07-23T18:09:55.173Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05585125"
    },
    {
      "nct_id": "NCT04047355",
      "title": "Propranolol for Challenging Behaviors in Autism",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Autism Spectrum Disorder",
        "Developmental Disability",
        "Aggression",
        "Self-Injurious Behavior",
        "Challenging Behavior"
      ],
      "interventions": [
        {
          "name": "Propranolol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "12 Years to 30 Years"
      },
      "enrollment_count": 8,
      "start_date": "2021-02-11",
      "completion_date": "2023-09-30",
      "has_results": true,
      "last_update_posted_date": "2025-06-04",
      "last_synced_at": "2026-07-23T18:09:55.173Z",
      "location_count": 1,
      "location_summary": "New Brunswick, New Jersey",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04047355"
    },
    {
      "nct_id": "NCT00006398",
      "title": "Prevention of Esophageal Varices by Beta-Adrenergic Blockers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Esophageal and Gastric Varices",
        "Liver Cirrhosis",
        "Portal Hypertension"
      ],
      "interventions": [
        {
          "name": "Timolol Maleate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 213,
      "start_date": "1993-08",
      "completion_date": "2002-09",
      "has_results": false,
      "last_update_posted_date": "2017-06-01",
      "last_synced_at": "2026-07-23T18:09:55.173Z",
      "location_count": 3,
      "location_summary": "New Haven, Connecticut • West Haven, Connecticut • Boston, Massachusetts",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "West Haven",
          "state": "Connecticut"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00006398"
    },
    {
      "nct_id": "NCT05414331",
      "title": "WithDRawal Impact Of Postoperative Beta-Blocker",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Coronary Artery Bypass"
      ],
      "interventions": [
        {
          "name": "Discontinuing all beta-blocker",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 43,
      "start_date": "2022-11-04",
      "completion_date": "2024-05-30",
      "has_results": false,
      "last_update_posted_date": "2025-04-06",
      "last_synced_at": "2026-07-23T18:09:55.173Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05414331"
    },
    {
      "nct_id": "NCT00211172",
      "title": "HMO Research Network CERT: Acute Myocardial Infarction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Myocardial Infarction (AMI)"
      ],
      "interventions": [
        {
          "name": "Beta-blocker adherence after an AMI",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 836,
      "start_date": "2003-10",
      "completion_date": "2009-05",
      "has_results": true,
      "last_update_posted_date": "2014-10-09",
      "last_synced_at": "2026-07-23T18:09:55.173Z",
      "location_count": 4,
      "location_summary": "Atlanta, Georgia • Boston, Massachusetts • Minneapolis, Minnesota + 1 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00211172"
    },
    {
      "nct_id": "NCT00060931",
      "title": "Effect Of Carvedilol Versus Metoprolol On Glycemic Control In Patients With Type II Diabetes And Hypertension",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "carvedilol",
          "type": "DRUG"
        },
        {
          "name": "metoprolol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "30 Years to 80 Years"
      },
      "enrollment_count": 501,
      "start_date": "2001-06",
      "completion_date": "2004-04",
      "has_results": false,
      "last_update_posted_date": "2015-04-14",
      "last_synced_at": "2026-07-23T18:09:55.173Z",
      "location_count": 119,
      "location_summary": "Birmingham, Alabama • Columbia, Alabama • Mobile, Alabama + 97 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Columbia",
          "state": "Alabama"
        },
        {
          "city": "Mobile",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00060931"
    },
    {
      "nct_id": "NCT02746575",
      "title": "Pilot - Peri-operative Beta Blockade",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Adrenergic Beta-Receptor Blockader",
        "Troponin Levels",
        "Cardiomyopathy, Post-surgical"
      ],
      "interventions": [
        {
          "name": "metoprolol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "51 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "51 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2015-11",
      "completion_date": "2017-10",
      "has_results": true,
      "last_update_posted_date": "2020-01-30",
      "last_synced_at": "2026-07-23T18:09:55.173Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02746575"
    },
    {
      "nct_id": "NCT00430612",
      "title": "The PACE-MI Registry Study - Outcomes of Beta-blocker Therapy After Myocardial Infarction (OBTAIN)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Myocardial Infarction"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "30 Years and older"
      },
      "enrollment_count": 7057,
      "start_date": "2009-05",
      "completion_date": "2015-10",
      "has_results": false,
      "last_update_posted_date": "2023-04-24",
      "last_synced_at": "2026-07-23T18:09:55.173Z",
      "location_count": 22,
      "location_summary": "Little Rock, Arkansas • Long Beach, California • Los Angeles, California + 19 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Bridgeport",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00430612"
    },
    {
      "nct_id": "NCT01099397",
      "title": "Antihypertensive Medication Exposure as Risk for Impaired Glucose Tolerance: A PEAR Sub-Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Prediabetic State"
      ],
      "interventions": [
        {
          "name": "Oral glucose tolerance test",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 26,
      "start_date": "2009-05",
      "completion_date": "2010-12",
      "has_results": true,
      "last_update_posted_date": "2018-04-03",
      "last_synced_at": "2026-07-23T18:09:55.173Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01099397"
    }
  ]
}