{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Adverse+Reaction+to+Drug",
    "query": {
      "condition": "Adverse Reaction to Drug"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 180,
    "total_pages": 18,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Adverse+Reaction+to+Drug&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T03:39:25.891Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02012712",
      "title": "Personal Health Records and Elder Medication Use Quality",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adverse Reaction to Drug",
        "Health Behavior",
        "Medication Adherence",
        "Physician-Patient Relations"
      ],
      "interventions": [
        {
          "name": "Personal Health Record (PHR)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "65 Years to 95 Years"
      },
      "enrollment_count": 1163,
      "start_date": "2010-07",
      "completion_date": "2011-02",
      "has_results": false,
      "last_update_posted_date": "2019-08-28",
      "last_synced_at": "2026-05-22T03:39:25.891Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02012712"
    },
    {
      "nct_id": "NCT00198419",
      "title": "Hypersensitivity Reaction to Vitrase (Ovine Hyaluronidase)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Drug Hypersensitivity"
      ],
      "interventions": [
        {
          "name": "Vitrase",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bausch & Lomb Incorporated",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2004-03",
      "completion_date": "2004-03",
      "has_results": false,
      "last_update_posted_date": "2013-03-14",
      "last_synced_at": "2026-05-22T03:39:25.891Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00198419"
    },
    {
      "nct_id": "NCT01747772",
      "title": "Sonoelastography: Ultrasound Method to Measure Liver Fibrosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Liver Disease",
        "Non-Alcoholic Fatty Liver Disease",
        "Hepatitis C Virus (HCV) Coinfection",
        "Hepatitis B Virus (HBV)",
        "Drug-Induced Liver Injury"
      ],
      "interventions": [
        {
          "name": "Shear Wave Sonoelastography",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 180,
      "start_date": "2010-02",
      "completion_date": "2014-02-14",
      "has_results": true,
      "last_update_posted_date": "2017-06-14",
      "last_synced_at": "2026-05-22T03:39:25.891Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01747772"
    },
    {
      "nct_id": "NCT04196777",
      "title": "Audit-and-feedback to Improve Antimicrobial-prescribing Among Urologists",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Urologic Diseases",
        "Antibacterial Drug Adverse Reaction"
      ],
      "interventions": [
        {
          "name": "Audit-and-feedback",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Iowa City Veterans Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 525,
      "start_date": "2022-08-01",
      "completion_date": "2023-08-31",
      "has_results": true,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-05-22T03:39:25.891Z",
      "location_count": 3,
      "location_summary": "Gainesville, Florida • Iowa City, Iowa • New York, New York",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04196777"
    },
    {
      "nct_id": "NCT04397445",
      "title": "Clinical Study to Investigate the Urinary Excretion of N-nitrosodimethylamine (NDMA) After Ranitidine Administration",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Ranitidine Adverse Reaction",
        "Pharmacokinetics",
        "Food-drug Interaction"
      ],
      "interventions": [
        {
          "name": "Ranitidine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Low nitrite/NDMA meals",
          "type": "OTHER"
        },
        {
          "name": "High nitrite/NDMA meals",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Food and Drug Administration (FDA)",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 18,
      "start_date": "2020-06-08",
      "completion_date": "2020-07-01",
      "has_results": true,
      "last_update_posted_date": "2021-08-09",
      "last_synced_at": "2026-05-22T03:39:25.891Z",
      "location_count": 1,
      "location_summary": "West Bend, Wisconsin",
      "locations": [
        {
          "city": "West Bend",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04397445"
    },
    {
      "nct_id": "NCT06970223",
      "title": "A Study to Investigate if Long Acting Cabotegravir (CAB) and Lenacapavir (LEN) Injections Are Tolerable and Acceptable When Administered to Healthy Adults Without HIV",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "Cabotegravir long-acting",
          "type": "DRUG"
        },
        {
          "name": "Lenacapavir long-acting",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "ViiV Healthcare",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2025-04-22",
      "completion_date": "2026-07-10",
      "has_results": false,
      "last_update_posted_date": "2025-11-28",
      "last_synced_at": "2026-05-22T03:39:25.891Z",
      "location_count": 1,
      "location_summary": "Long Beach, California",
      "locations": [
        {
          "city": "Long Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06970223"
    },
    {
      "nct_id": "NCT00047476",
      "title": "D-MPH in the Treatment of Fatigue and Neurobehavioral Function Related to Chemotherapy in Adult Cancer Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fatigue",
        "Neoplasms"
      ],
      "interventions": [
        {
          "name": "dexmethylphenidate(d-mph)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Celgene Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 160,
      "start_date": "2002-06",
      "completion_date": "2004-03",
      "has_results": false,
      "last_update_posted_date": "2005-06-24",
      "last_synced_at": "2026-05-22T03:39:25.891Z",
      "location_count": 21,
      "location_summary": "Birmingham, Alabama • Flagstaff, Arizona • Tucson, Arizona + 17 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Flagstaff",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Berkeley",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00047476"
    },
    {
      "nct_id": "NCT03748355",
      "title": "Using Pharmacogenetics to Identify Patients With Polypharmacy at Risk of Medication Adverse Effects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Psychiatric Disorder"
      ],
      "interventions": [
        {
          "name": "Pharmacogentic Analysis",
          "type": "GENETIC"
        }
      ],
      "intervention_types": [
        "GENETIC"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2018-10-14",
      "completion_date": "2020-01-02",
      "has_results": false,
      "last_update_posted_date": "2020-03-11",
      "last_synced_at": "2026-05-22T03:39:25.891Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03748355"
    },
    {
      "nct_id": "NCT03287622",
      "title": "Evaluation of an Interactive Opioid Risk Education Program (STOMP) for Parents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain, Postoperative",
        "Medication Adherence",
        "Opioid Use",
        "Knowledge, Attitudes, Practice",
        "Risk Reduction Behavior"
      ],
      "interventions": [
        {
          "name": "Educational Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nudge",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "21 Years to 99 Years"
      },
      "enrollment_count": 712,
      "start_date": "2017-10-24",
      "completion_date": "2019-09-30",
      "has_results": true,
      "last_update_posted_date": "2020-11-19",
      "last_synced_at": "2026-05-22T03:39:25.891Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03287622"
    },
    {
      "nct_id": "NCT06789601",
      "title": "Evaluating Informatics-assisted Immune-related Adverse Event Detection to Improve Registration Onto a Biorepository",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Malignancy",
        "Immune Related Adverse Events"
      ],
      "interventions": [
        {
          "name": "Informatics system for eligibility monitoring",
          "type": "OTHER"
        },
        {
          "name": "Standard eligibility monitoring",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 100,
      "start_date": "2025-06-17",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-06-19",
      "last_synced_at": "2026-05-22T03:39:25.891Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06789601"
    }
  ]
}