{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Affective+Symptoms",
    "query": {
      "condition": "Affective Symptoms"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 122,
    "total_pages": 13,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Affective+Symptoms&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:21:40.428Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04048720",
      "title": "Norwalk Feasibility Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Behavior Problem",
        "Development Delay",
        "Emotional Disturbances",
        "Family Conflict",
        "Relation, Mother-Child"
      ],
      "interventions": [
        {
          "name": "Family Nurture Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "24 Months",
        "maximum_age": "78 Months",
        "sex": "ALL",
        "summary": "24 Months to 78 Months"
      },
      "enrollment_count": 38,
      "start_date": "2019-07-05",
      "completion_date": "2019-10-01",
      "has_results": false,
      "last_update_posted_date": "2020-11-09",
      "last_synced_at": "2026-05-22T08:21:40.428Z",
      "location_count": 1,
      "location_summary": "Norwalk, Connecticut",
      "locations": [
        {
          "city": "Norwalk",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04048720"
    },
    {
      "nct_id": "NCT04902469",
      "title": "Cognitive and Affective Mechanisms Underlying an Olfactory Approach to Modify Cigarette Craving",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Craving"
      ],
      "interventions": [
        {
          "name": "Pleasant Odor",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Odor Blank",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "18 Years to 49 Years"
      },
      "enrollment_count": 250,
      "start_date": "2021-12-01",
      "completion_date": "2026-06",
      "has_results": false,
      "last_update_posted_date": "2025-07-03",
      "last_synced_at": "2026-05-22T08:21:40.428Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04902469"
    },
    {
      "nct_id": "NCT02150369",
      "title": "Interleukin-2-Induced Cognitive/Affective/Sleep Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Metastatic Renal Cell Carcinoma",
        "Metastatic Melanoma",
        "High-dose Interleukin-2"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "16 Years to 65 Years"
      },
      "enrollment_count": 32,
      "start_date": "2015-02-16",
      "completion_date": "2017-03-02",
      "has_results": false,
      "last_update_posted_date": "2017-05-31",
      "last_synced_at": "2026-05-22T08:21:40.428Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02150369"
    },
    {
      "nct_id": "NCT00001545",
      "title": "Evaluation of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Mood Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Bipolar Disorder",
        "Mood Disorder",
        "Unipolar Depression"
      ],
      "interventions": [
        {
          "name": "Magstim Super Rapid Magnetic Stimulator",
          "type": "DEVICE"
        },
        {
          "name": "Cadwell MES-10",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 91,
      "start_date": "1996-05",
      "completion_date": "2006-07",
      "has_results": false,
      "last_update_posted_date": "2006-07-13",
      "last_synced_at": "2026-05-22T08:21:40.428Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001545"
    },
    {
      "nct_id": "NCT02970565",
      "title": "Family Nurture Intervention, A Group Model in Connecticut",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Behavior Problem",
        "Development Delay",
        "Emotional Disturbance",
        "Family Conflict"
      ],
      "interventions": [
        {
          "name": "Family Nurture Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nutrition and Play Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "24 Months",
        "maximum_age": "54 Months",
        "sex": "ALL",
        "summary": "24 Months to 54 Months"
      },
      "enrollment_count": 106,
      "start_date": "2016-10",
      "completion_date": "2019-05",
      "has_results": false,
      "last_update_posted_date": "2023-02-15",
      "last_synced_at": "2026-05-22T08:21:40.428Z",
      "location_count": 1,
      "location_summary": "Cos Cob, Connecticut",
      "locations": [
        {
          "city": "Cos Cob",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02970565"
    },
    {
      "nct_id": "NCT06125964",
      "title": "eMOTION Formative Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Physical Inactivity",
        "Overweight or Obesity",
        "Cancer"
      ],
      "interventions": [
        {
          "name": "Intensity-Based Goals",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Affect-Based Goals",
          "type": "BEHAVIORAL"
        },
        {
          "name": "TYPE/CONTEXT Enhancement",
          "type": "BEHAVIORAL"
        },
        {
          "name": "SAVOR Enhancement",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 47,
      "start_date": "2023-10-06",
      "completion_date": "2024-06-30",
      "has_results": true,
      "last_update_posted_date": "2025-08-14",
      "last_synced_at": "2026-05-22T08:21:40.428Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06125964"
    },
    {
      "nct_id": "NCT06758414",
      "title": "CBT-CP for Veterans With SMI",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain",
        "Schizophrenia",
        "Psychotic Disorders",
        "Bipolar Disorder",
        "Affective Disorders, Psychotic"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy for Chronic Pain (CBT-CP)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health & Wellness (H&W)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 190,
      "start_date": "2026-02-01",
      "completion_date": "2029-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-09",
      "last_synced_at": "2026-05-22T08:21:40.428Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06758414"
    },
    {
      "nct_id": "NCT04159168",
      "title": "Facial Affect Sensitivity Training for Young Children With Callous-unemotional Traits",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Affective Symptoms",
        "Empathy"
      ],
      "interventions": [
        {
          "name": "Facial Affect Sensitivity Training (FAST)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Implicit Gaze Training task (Active control condition)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Alabama, Tuscaloosa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "11 Years",
        "sex": "ALL",
        "summary": "6 Years to 11 Years"
      },
      "enrollment_count": 168,
      "start_date": "2021-02-15",
      "completion_date": "2026-07-31",
      "has_results": false,
      "last_update_posted_date": "2025-06-15",
      "last_synced_at": "2026-05-22T08:21:40.428Z",
      "location_count": 1,
      "location_summary": "Tuscaloosa, Alabama",
      "locations": [
        {
          "city": "Tuscaloosa",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04159168"
    },
    {
      "nct_id": "NCT05623046",
      "title": "Building Emotional Self-Awareness Teletherapy (BEST)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Concussion, Mild",
        "Concussion, Brain",
        "Concussion, Severe",
        "Concussion, Intermediate",
        "Concussion; Syndrome",
        "Concussion Injury of Cerebrum",
        "Concussion with Brief Loss of Consciousness",
        "Alexithymia"
      ],
      "interventions": [
        {
          "name": "Treatment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2023-02-23",
      "completion_date": "2025-03-25",
      "has_results": false,
      "last_update_posted_date": "2025-04-01",
      "last_synced_at": "2026-05-22T08:21:40.428Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05623046"
    },
    {
      "nct_id": "NCT06662357",
      "title": "Family Connections",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Emotional Disturbance",
        "Behavior Disorders in Children"
      ],
      "interventions": [
        {
          "name": "Behavioral Treatment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Cambridge Health Alliance",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "3 Years to 18 Years"
      },
      "enrollment_count": 300,
      "start_date": "2025-01-30",
      "completion_date": "2028-09-29",
      "has_results": false,
      "last_update_posted_date": "2025-06-26",
      "last_synced_at": "2026-05-22T08:21:40.428Z",
      "location_count": 1,
      "location_summary": "Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06662357"
    }
  ]
}