{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Aggressive+Childhood+Behavior",
    "query": {
      "condition": "Aggressive Childhood Behavior"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 23,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Aggressive+Childhood+Behavior&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T01:50:41.291Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00796302",
      "title": "Treatment of Severe Childhood Aggression (The TOSCA Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Attention Deficit Disorder With Hyperactivity"
      ],
      "interventions": [
        {
          "name": "Methylphenidate HCl",
          "type": "DRUG"
        },
        {
          "name": "Risperidone",
          "type": "DRUG"
        },
        {
          "name": "Parent Management Training (PMT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Michael Aman",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "6 Years to 12 Years"
      },
      "enrollment_count": 168,
      "start_date": "2008-08",
      "completion_date": "2012-11",
      "has_results": true,
      "last_update_posted_date": "2017-07-26",
      "last_synced_at": "2026-05-22T01:50:41.291Z",
      "location_count": 4,
      "location_summary": "Stony Brook, New York • Cleveland, Ohio • Columbus, Ohio + 1 more",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00796302"
    },
    {
      "nct_id": "NCT04087772",
      "title": "Enhancing School-Based Violence Prevention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aggressive Childhood Behavior"
      ],
      "interventions": [
        {
          "name": "Mental Health Enhanced Positive Behavioral Interventions and Supports (PBIS-MH)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Racial/Ethnic Discrimination Interventions (RED)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "105 Years",
        "sex": "ALL",
        "summary": "10 Years to 105 Years"
      },
      "enrollment_count": 4840,
      "start_date": "2019-09-13",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-20",
      "last_synced_at": "2026-05-22T01:50:41.291Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04087772"
    },
    {
      "nct_id": "NCT07091279",
      "title": "Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Autism Spectrum Disorder",
        "Challenging Behaviour",
        "Aggression",
        "Severe Disruptive Behaviour Disorders",
        "Self-injury"
      ],
      "interventions": [
        {
          "name": "Propranolol",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jeremy Veenstra-vanderweele",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "12 Years to 40 Years"
      },
      "enrollment_count": 60,
      "start_date": "2026-01-30",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-30",
      "last_synced_at": "2026-05-22T01:50:41.291Z",
      "location_count": 2,
      "location_summary": "Staten Island, New York • White Plains, New York",
      "locations": [
        {
          "city": "Staten Island",
          "state": "New York"
        },
        {
          "city": "White Plains",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07091279"
    },
    {
      "nct_id": "NCT00410657",
      "title": "Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplant",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Breast Cancer",
        "Chronic Myeloproliferative Disorders",
        "Gestational Trophoblastic Tumor",
        "Graft Versus Host Disease",
        "Leukemia",
        "Lymphoma",
        "Multiple Myeloma and Plasma Cell Neoplasm",
        "Myelodysplastic Syndromes",
        "Myelodysplastic/Myeloproliferative Diseases",
        "Neuroblastoma",
        "Ovarian Cancer",
        "Testicular Germ Cell Tumor"
      ],
      "interventions": [
        {
          "name": "alemtuzumab",
          "type": "BIOLOGICAL"
        },
        {
          "name": "methylprednisolone",
          "type": "DRUG"
        },
        {
          "name": "prednisone",
          "type": "DRUG"
        },
        {
          "name": "flow cytometry",
          "type": "OTHER"
        },
        {
          "name": "immunologic technique",
          "type": "OTHER"
        },
        {
          "name": "pharmacological study",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Fred Hutchinson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 53,
      "start_date": "2006-07",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2010-05-14",
      "last_synced_at": "2026-05-22T01:50:41.291Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00410657"
    },
    {
      "nct_id": "NCT05925101",
      "title": "Basic and Applied Research on Extinction Bursts",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Problem Behavior",
        "Aggression",
        "Self Injury"
      ],
      "interventions": [
        {
          "name": "Extinction-only condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Rate-drop condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Rate-hold condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Magnitude-drop condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Magnitude-hold condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Quality-drop condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Quality-hold condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Rate-drop/quality-increase condition",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "3 Years to 17 Years"
      },
      "enrollment_count": 40,
      "start_date": "2023-07-07",
      "completion_date": "2028-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-05-22T01:50:41.291Z",
      "location_count": 1,
      "location_summary": "Somerset, New Jersey",
      "locations": [
        {
          "city": "Somerset",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05925101"
    },
    {
      "nct_id": "NCT00308074",
      "title": "An Open-Label Trial of Aripiprazole in Autism Spectrum Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Autism",
        "Asperger's Disorder",
        "Pervasive Developmental Disorder"
      ],
      "interventions": [
        {
          "name": "Aripiprazole",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cambridge Health Alliance",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Years to 17 Years"
      },
      "enrollment_count": 14,
      "start_date": "2006-02",
      "completion_date": "2009-02",
      "has_results": true,
      "last_update_posted_date": "2017-02-15",
      "last_synced_at": "2026-05-22T01:50:41.291Z",
      "location_count": 1,
      "location_summary": "Medford, Massachusetts",
      "locations": [
        {
          "city": "Medford",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00308074"
    },
    {
      "nct_id": "NCT01631851",
      "title": "Cognitive-Behavioral Therapy for Irritability in Adolescents With High Functioning Autism Spectrum Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autism",
        "Autism Spectrum Disorder (ASD",
        "Asperger's Disorder",
        "Pervasive Developmental Disorder (PDD-NOS)"
      ],
      "interventions": [
        {
          "name": "Cognitive-Behavioral Therapy (CBT) for Irritability",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "9 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "9 Years to 16 Years"
      },
      "enrollment_count": 9,
      "start_date": "2011-05",
      "completion_date": "2013-04-23",
      "has_results": false,
      "last_update_posted_date": "2023-11-18",
      "last_synced_at": "2026-05-22T01:50:41.291Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01631851"
    },
    {
      "nct_id": "NCT01965184",
      "title": "Cognitive-Behavioral Therapy for Disruptive Behavior in Children and Adolescents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Disruptive Behavior",
        "Aggression",
        "Anger",
        "Irritability",
        "Noncompliance"
      ],
      "interventions": [
        {
          "name": "Cognitive-Behavioral Therapy for Anger and Aggression",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Supportive Psychotherapy (SPT)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "8 Years to 16 Years"
      },
      "enrollment_count": 101,
      "start_date": "2013-11-14",
      "completion_date": "2018-11-03",
      "has_results": false,
      "last_update_posted_date": "2023-11-18",
      "last_synced_at": "2026-05-22T01:50:41.291Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01965184"
    },
    {
      "nct_id": "NCT00842439",
      "title": "Healthy Brains & Behavior: Understanding and Treating Youth Aggression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aggression"
      ],
      "interventions": [
        {
          "name": "CBI",
          "type": "BEHAVIORAL"
        },
        {
          "name": "NUT",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "11 Years to 12 Years"
      },
      "enrollment_count": 335,
      "start_date": "2009-02",
      "completion_date": "2012-08",
      "has_results": false,
      "last_update_posted_date": "2016-08-19",
      "last_synced_at": "2026-05-22T01:50:41.291Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00842439"
    },
    {
      "nct_id": "NCT01547052",
      "title": "Adapting Dialectical Behavior Therapy for Children in Residential Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Childhood Aggression"
      ],
      "interventions": [
        {
          "name": "DBT for children",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced Supportive-Educational therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "12 Years",
        "sex": "MALE",
        "summary": "6 Years to 12 Years · Male only"
      },
      "enrollment_count": 47,
      "start_date": "2011-04",
      "completion_date": "2016-09",
      "has_results": false,
      "last_update_posted_date": "2018-07-23",
      "last_synced_at": "2026-05-22T01:50:41.291Z",
      "location_count": 1,
      "location_summary": "Brewster, New York",
      "locations": [
        {
          "city": "Brewster",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01547052"
    }
  ]
}