{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Aging%2C+Biological&page=2",
    "query": {
      "condition": "Aging, Biological",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Aging%2C+Biological&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T07:09:05.174Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07220473",
      "title": "Tirzepatide to Slow Biological Aging",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Aging",
        "LONGEVITY 1"
      ],
      "interventions": [
        {
          "name": "Zepbound",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Medical Branch, Galveston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "55 Years to 70 Years"
      },
      "enrollment_count": 90,
      "start_date": "2026-02-27",
      "completion_date": "2028-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-24",
      "last_synced_at": "2026-06-11T07:09:05.174Z",
      "location_count": 1,
      "location_summary": "Galveston, Texas",
      "locations": [
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07220473"
    },
    {
      "nct_id": "NCT05570721",
      "title": "Depression, Aging, Stress and Heart Health Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Menopause",
        "Depression",
        "Heart Disease in Women",
        "Stress"
      ],
      "interventions": [
        {
          "name": "Trier Social Stress Test",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "44 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "44 Years to 55 Years · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2022-11-16",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-12-22",
      "last_synced_at": "2026-06-11T07:09:05.174Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05570721"
    },
    {
      "nct_id": "NCT01032733",
      "title": "Biological Effects of Weight Loss In Older, Obese Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Obesity",
        "Sarcopenia"
      ],
      "interventions": [
        {
          "name": "Lifestyle Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Educational Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "79 Years",
        "sex": "FEMALE",
        "summary": "55 Years to 79 Years · Female only"
      },
      "enrollment_count": 34,
      "start_date": "2006-09",
      "completion_date": "2009-10",
      "has_results": true,
      "last_update_posted_date": "2012-06-14",
      "last_synced_at": "2026-06-11T07:09:05.174Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01032733"
    },
    {
      "nct_id": "NCT00099697",
      "title": "Biologic Effects of Dehydroepiandrosterone (DHEA) in Humans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging",
        "Obesity",
        "Insulin Resistance"
      ],
      "interventions": [
        {
          "name": "DHEA",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute on Aging (NIA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "78 Years",
        "sex": "ALL",
        "summary": "65 Years to 78 Years"
      },
      "enrollment_count": 56,
      "start_date": "2001-06",
      "completion_date": "2004-02",
      "has_results": false,
      "last_update_posted_date": "2009-12-11",
      "last_synced_at": "2026-06-11T07:09:05.174Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00099697"
    },
    {
      "nct_id": "NCT03440099",
      "title": "Sex-specific Adaptation to Resistance Training in Older Adults",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Biological Aging"
      ],
      "interventions": [
        {
          "name": "Resistance exercise training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Massachusetts, Amherst",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "65 Years to 75 Years"
      },
      "enrollment_count": 50,
      "start_date": "2018-01-01",
      "completion_date": "2024-03-31",
      "has_results": false,
      "last_update_posted_date": "2022-06-28",
      "last_synced_at": "2026-06-11T07:09:05.174Z",
      "location_count": 1,
      "location_summary": "Amherst, Massachusetts",
      "locations": [
        {
          "city": "Amherst",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03440099"
    },
    {
      "nct_id": "NCT07218445",
      "title": "The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Obesity",
        "Menopause Hot Flashes"
      ],
      "interventions": [
        {
          "name": "Tirzepatide",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "46 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "46 Years to 60 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2026-04-08",
      "completion_date": "2027-09-18",
      "has_results": false,
      "last_update_posted_date": "2026-06-05",
      "last_synced_at": "2026-06-11T07:09:05.174Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07218445"
    },
    {
      "nct_id": "NCT02404792",
      "title": "Exercise for Healthy Aging: The Impact of HIV and Aging on Physical Function and the Somatopause",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV",
        "Inflammation",
        "Obesity",
        "Aging, Biological"
      ],
      "interventions": [
        {
          "name": "High-intensity cardiovascular and resistance exercise",
          "type": "OTHER"
        },
        {
          "name": "Moderate-intensity cardiovascular and resistance exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "50 Years to 75 Years"
      },
      "enrollment_count": 69,
      "start_date": "2015-04",
      "completion_date": "2018-03-01",
      "has_results": true,
      "last_update_posted_date": "2019-01-16",
      "last_synced_at": "2026-06-11T07:09:05.174Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02404792"
    },
    {
      "nct_id": "NCT00318864",
      "title": "Biological CVD Risk Factors in Older Depressed Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Hypertension",
        "Hypercholesterolemia"
      ],
      "interventions": [
        {
          "name": "Cognitive behavioral therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2002-06",
      "completion_date": "2005-07",
      "has_results": false,
      "last_update_posted_date": "2006-04-27",
      "last_synced_at": "2026-06-11T07:09:05.174Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00318864"
    },
    {
      "nct_id": "NCT07354620",
      "title": "A Pilot Study on Reverse Aging (The REVERSE Study)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Aging"
      ],
      "interventions": [
        {
          "name": "Rapamycin (Tablets)",
          "type": "DRUG"
        },
        {
          "name": "Prolon diet",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "The Christ Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 52,
      "start_date": "2025-02-15",
      "completion_date": "2026-05",
      "has_results": false,
      "last_update_posted_date": "2026-01-21",
      "last_synced_at": "2026-06-11T07:09:05.174Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07354620"
    },
    {
      "nct_id": "NCT05651620",
      "title": "The CALERIE™ Legacy Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Calorie Restriction"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "33 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "33 Years to 70 Years"
      },
      "enrollment_count": 216,
      "start_date": "2023-04-06",
      "completion_date": "2028-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-09",
      "last_synced_at": "2026-06-11T07:09:05.174Z",
      "location_count": 3,
      "location_summary": "Baton Rouge, Louisiana • Boston, Massachusetts • St Louis, Missouri",
      "locations": [
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05651620"
    }
  ]
}