{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Alpha-Synucleinopathy&page=2",
    "query": {
      "condition": "Alpha-Synucleinopathy",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Alpha-Synucleinopathy&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T11:40:51.825Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07217054",
      "title": "Colonic Tissue Biopsy Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis or REM Sleep Behavior Disorder",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "PARKINSON DISEASE (Disorder)",
        "Parkinson",
        "Parkinson s Disease",
        "Parkinson Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "CND Life Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "40 Years to 99 Years"
      },
      "enrollment_count": 40,
      "start_date": "2025-11-04",
      "completion_date": "2029-10",
      "has_results": false,
      "last_update_posted_date": "2026-02-11",
      "last_synced_at": "2026-07-24T11:40:51.825Z",
      "location_count": 1,
      "location_summary": "Branford, Connecticut",
      "locations": [
        {
          "city": "Branford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07217054"
    },
    {
      "nct_id": "NCT02046434",
      "title": "Phenylbutyrate Response as a Biomarker for Alpha-synuclein Clearance From the Brain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Parkinson's Disease"
      ],
      "interventions": [
        {
          "name": "Glycerol Phenylbutyrate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 38,
      "start_date": "2014-01",
      "completion_date": "2019-09",
      "has_results": false,
      "last_update_posted_date": "2022-04-25",
      "last_synced_at": "2026-07-24T11:40:51.825Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02046434"
    },
    {
      "nct_id": "NCT04020198",
      "title": "A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Parkinson Disease",
        "Multiple System Atrophy",
        "Rapid Eye Movement Sleep Behavior Disorder",
        "Normal Pressure Hydrocephalus"
      ],
      "interventions": [
        {
          "name": "Biomarker assay",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Stony Brook University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "50 Years to 75 Years"
      },
      "enrollment_count": 8,
      "start_date": "2020-01-15",
      "completion_date": "2022-10-19",
      "has_results": false,
      "last_update_posted_date": "2025-04-06",
      "last_synced_at": "2026-07-24T11:40:51.825Z",
      "location_count": 1,
      "location_summary": "Stony Brook, New York",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04020198"
    },
    {
      "nct_id": "NCT03170063",
      "title": "FoxBioNet Pilot Project: SAVE (Synuclein Assay Validation Effort)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "Procedure/Surgery: Biofluid samplings",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Michael J. Fox Foundation for Parkinson's Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "30 Years and older"
      },
      "enrollment_count": 54,
      "start_date": "2017-08-08",
      "completion_date": "2018-03-12",
      "has_results": false,
      "last_update_posted_date": "2018-08-20",
      "last_synced_at": "2026-07-24T11:40:51.825Z",
      "location_count": 5,
      "location_summary": "Chicago, Illinois • Boston, Massachusetts • Portland, Oregon + 2 more",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03170063"
    },
    {
      "nct_id": "NCT03133611",
      "title": "Detecting Parkinson's Disease Through Speech Analysis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson Disease",
        "REM Sleep Behavior Disorder"
      ],
      "interventions": [
        {
          "name": "Speech assessment",
          "type": "OTHER"
        },
        {
          "name": "Routine clinical assessment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Czech Technical University in Prague",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "50 Years to 80 Years"
      },
      "enrollment_count": 350,
      "start_date": "2017-04-01",
      "completion_date": "2020-12-31",
      "has_results": false,
      "last_update_posted_date": "2019-08-09",
      "last_synced_at": "2026-07-24T11:40:51.825Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03133611"
    },
    {
      "nct_id": "NCT05757206",
      "title": "The Syn-Sleep Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "REM Sleep Behavior Disorder (iRBD)"
      ],
      "interventions": [
        {
          "name": "Syn-One Test",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "CND Life Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 80,
      "start_date": "2022-09-15",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-01-15",
      "last_synced_at": "2026-07-24T11:40:51.825Z",
      "location_count": 8,
      "location_summary": "Chandler, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 5 more",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05757206"
    },
    {
      "nct_id": "NCT07204652",
      "title": "Colonoscopic Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "PARKINSON DISEASE (Disorder)",
        "Parkinson",
        "Parkinson's Disease and Parkinsonism",
        "Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "No Intervention: Observational Cohort",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "CND Life Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "40 Years to 99 Years"
      },
      "enrollment_count": 20,
      "start_date": "2025-09-03",
      "completion_date": "2029-09",
      "has_results": false,
      "last_update_posted_date": "2026-02-11",
      "last_synced_at": "2026-07-24T11:40:51.825Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07204652"
    },
    {
      "nct_id": "NCT04518059",
      "title": "Misfolded Proteins in the Skin of People With Parkinson's Disease and Other Parkinsonism",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Parkinson Disease",
        "Parkinsonism",
        "Dementia With Lewy Bodies",
        "Multiple System Atrophy",
        "Progressive Supranuclear Palsy",
        "Corticobasal Degeneration"
      ],
      "interventions": [
        {
          "name": "punch skin biopsy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University Hospitals Cleveland Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "21 Years to 89 Years"
      },
      "enrollment_count": 184,
      "start_date": "2019-03-12",
      "completion_date": "2025-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-01",
      "last_synced_at": "2026-07-24T11:40:51.825Z",
      "location_count": 2,
      "location_summary": "Cleveland, Ohio • South Euclid, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "South Euclid",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04518059"
    },
    {
      "nct_id": "NCT02459886",
      "title": "Single-Ascending Dose Study of BIIB054 in Healthy Participants and Early Parkinson's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Parkinson's Disease",
        "Healthy"
      ],
      "interventions": [
        {
          "name": "BIIB054",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Biogen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 66,
      "start_date": "2015-07-01",
      "completion_date": "2017-11-20",
      "has_results": false,
      "last_update_posted_date": "2019-08-08",
      "last_synced_at": "2026-07-24T11:40:51.825Z",
      "location_count": 9,
      "location_summary": "Washington D.C., District of Columbia • Hallandale, Florida • Oviedo, Florida + 6 more",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Hallandale",
          "state": "Florida"
        },
        {
          "city": "Oviedo",
          "state": "Florida"
        },
        {
          "city": "Evansville",
          "state": "Indiana"
        },
        {
          "city": "Farmington Hills",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02459886"
    },
    {
      "nct_id": "NCT03623672",
      "title": "North American Prodromal Synucleinopathy Consortium",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "REM Sleep Behavior Disorder",
        "Parkinson Disease",
        "Lewy Body Disease",
        "Dementia With Lewy Bodies",
        "Multiple System Atrophy",
        "REM Sleep Parasomnias"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2018-08-29",
      "completion_date": "2026-07-31",
      "has_results": false,
      "last_update_posted_date": "2024-11-06",
      "last_synced_at": "2026-07-24T11:40:51.825Z",
      "location_count": 9,
      "location_summary": "Sun City, Arizona • Los Angeles, California • Redwood City, California + 6 more",
      "locations": [
        {
          "city": "Sun City",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Redwood City",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03623672"
    }
  ]
}