{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Alpha-amylase",
    "query": {
      "condition": "Alpha-amylase"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T07:27:49.065Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03530943",
      "title": "Pet Partners for Promotion of Academic Life Skills",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress Prevention",
        "Cortisol",
        "Anxiety Disorders and Symptoms",
        "Depression Disorders and Symptoms",
        "Executive Functioning",
        "Motivation and Learning",
        "Momentary Emotion",
        "Study Strategies",
        "Perceived Stress",
        "Animal Behavior",
        "Animal Stress",
        "Dyadic Interaction",
        "Alpha-amylase"
      ],
      "interventions": [
        {
          "name": "Animal Assisted Activities",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Academic Stress Management tools",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Washington State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 300,
      "start_date": "2016-08",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2018-05-21",
      "last_synced_at": "2026-06-10T07:27:49.065Z",
      "location_count": 1,
      "location_summary": "Pullman, Washington",
      "locations": [
        {
          "city": "Pullman",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03530943"
    },
    {
      "nct_id": "NCT02490280",
      "title": "Examining Cortisol and Alpha Amylase in a Healthy Sample of Youth and Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "Trier Social Stress Test",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "34 Years",
        "sex": "ALL",
        "summary": "11 Years to 34 Years"
      },
      "enrollment_count": 50,
      "start_date": "2013-04",
      "completion_date": "2015-04",
      "has_results": false,
      "last_update_posted_date": "2015-07-03",
      "last_synced_at": "2026-06-10T07:27:49.065Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02490280"
    },
    {
      "nct_id": "NCT01196117",
      "title": "Sleepiness and the Effects of CPAP on Salivary Cortisol and Alpha-Amylase Levels in Patients With Sleep Apnea",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Apnea",
        "Sleep Disordered Breathing"
      ],
      "interventions": [
        {
          "name": "14 days of placebo therapy",
          "type": "DEVICE"
        },
        {
          "name": "14 days of CPAP therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 18,
      "start_date": "2004-11-15",
      "completion_date": "2011-12-15",
      "has_results": true,
      "last_update_posted_date": "2020-04-01",
      "last_synced_at": "2026-06-10T07:27:49.065Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01196117"
    },
    {
      "nct_id": "NCT04004520",
      "title": "Feasibility of Collecting Stress Biomarkers Among Youth Experiencing Homelessness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress, Physiological"
      ],
      "interventions": [
        {
          "name": "Virtual Reality with Meditation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Audio Control",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Virtual reality Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "24 Years",
        "sex": "ALL",
        "summary": "18 Years to 24 Years"
      },
      "enrollment_count": 30,
      "start_date": "2019-07-24",
      "completion_date": "2019-08-19",
      "has_results": false,
      "last_update_posted_date": "2022-07-13",
      "last_synced_at": "2026-06-10T07:27:49.065Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04004520"
    },
    {
      "nct_id": "NCT07079683",
      "title": "RCT: Enzyme Blend Toothpaste on Dental Biofilm Plaque Accumulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Biofilm Accumulation"
      ],
      "interventions": [
        {
          "name": "Toothpaste Product",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Novozymes A/S",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 132,
      "start_date": "2023-10-30",
      "completion_date": "2023-12-13",
      "has_results": false,
      "last_update_posted_date": "2025-08-08",
      "last_synced_at": "2026-06-10T07:27:49.065Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07079683"
    },
    {
      "nct_id": "NCT06730425",
      "title": "Examining Stress Salivary Biomarkers in Pediatric Patients Undergoing Dental Procedures",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dental Anxiety",
        "Dental Fear",
        "Stress",
        "Pediatric Population"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Midwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "7 Years to 17 Years"
      },
      "enrollment_count": 66,
      "start_date": "2024-09-09",
      "completion_date": "2025-05-30",
      "has_results": false,
      "last_update_posted_date": "2025-08-17",
      "last_synced_at": "2026-06-10T07:27:49.065Z",
      "location_count": 1,
      "location_summary": "Downers Grove, Illinois",
      "locations": [
        {
          "city": "Downers Grove",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06730425"
    },
    {
      "nct_id": "NCT00831194",
      "title": "Stress, Dietary Lapse and Weight Loss Among Adults With Type 2 Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Type 2 Diabetes"
      ],
      "interventions": [
        {
          "name": "Personalized diet plan and PDA self reporting.",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins Bloomberg School of Public Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 70,
      "start_date": "2009-03",
      "completion_date": "2012-07",
      "has_results": false,
      "last_update_posted_date": "2012-08-02",
      "last_synced_at": "2026-06-10T07:27:49.065Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00831194"
    },
    {
      "nct_id": "NCT03854539",
      "title": "Salivary Alpha Amylase as a Biomarker of Transdermal Vagus Nerve Stimulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "No Condition Salivary Alpha Amylase"
      ],
      "interventions": [
        {
          "name": "Transdermal Vagus Nerve Stimulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Arkansas Tech University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2018-03-31",
      "completion_date": "2020-06-08",
      "has_results": false,
      "last_update_posted_date": "2020-06-18",
      "last_synced_at": "2026-06-10T07:27:49.065Z",
      "location_count": 1,
      "location_summary": "Russellville, Arkansas",
      "locations": [
        {
          "city": "Russellville",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03854539"
    },
    {
      "nct_id": "NCT03786952",
      "title": "Stress, Sex, and the Generalization of Fear",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Psychological Stress"
      ],
      "interventions": [
        {
          "name": "Stress immediately before learning in males",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham control immediately before learning in males",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stress 30 minutes before learning in males",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham control 30 minutes before learning in males",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stress immediately before learning in females",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham control immediately before learning in females",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stress 30 minutes before learning in females",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham control 30 minutes before learning in females",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Ohio Northern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 606,
      "start_date": "2019-01-25",
      "completion_date": "2022-06-30",
      "has_results": true,
      "last_update_posted_date": "2023-03-23",
      "last_synced_at": "2026-06-10T07:27:49.065Z",
      "location_count": 1,
      "location_summary": "Ada, Ohio",
      "locations": [
        {
          "city": "Ada",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03786952"
    }
  ]
}