{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Altitude",
    "query": {
      "condition": "Altitude"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 74,
    "total_pages": 8,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Altitude&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:46:52.868Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03433651",
      "title": "Creatine Monohydrate Use for Preventing Altitude Induced Depression",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Depression"
      ],
      "interventions": [
        {
          "name": "Creatine monohydrate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mike O'Callaghan Military Hospital",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2019-01-01",
      "completion_date": "2019-01-07",
      "has_results": false,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-05-22T05:46:52.868Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03433651"
    },
    {
      "nct_id": "NCT04993729",
      "title": "Safety and Efficacy of T89 in the Prevention and Treatment of Adults With Acute Mountain Sickness (AMS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Acute Mountain Sickness (AMS)"
      ],
      "interventions": [
        {
          "name": "T89 capsule",
          "type": "DRUG"
        },
        {
          "name": "Placebo capsule",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tasly Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 853,
      "start_date": "2021-07-21",
      "completion_date": "2023-05-26",
      "has_results": false,
      "last_update_posted_date": "2024-08-13",
      "last_synced_at": "2026-05-22T05:46:52.868Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04993729"
    },
    {
      "nct_id": "NCT00498563",
      "title": "Effects of Mild Hypobaric Hypoxia on Sleep and Post-sleep Performance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Altitude",
        "Hypoxia",
        "Environmental Sleep Disorder"
      ],
      "interventions": [
        {
          "name": "altitude exposure in hypobaric chamber",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Oklahoma State University Center for Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "60 Years",
        "sex": "MALE",
        "summary": "30 Years to 60 Years · Male only"
      },
      "enrollment_count": 34,
      "start_date": "2006-10",
      "completion_date": "2007-08",
      "has_results": false,
      "last_update_posted_date": "2015-04-24",
      "last_synced_at": "2026-05-22T05:46:52.868Z",
      "location_count": 1,
      "location_summary": "Tulsa, Oklahoma",
      "locations": [
        {
          "city": "Tulsa",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00498563"
    },
    {
      "nct_id": "NCT03490916",
      "title": "Effect of Acetazolamide on Subclinical High-Altitude Pulmonary Edema Detected by Lung Ultrasonography",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "High Altitude Pulmonary Edema"
      ],
      "interventions": [
        {
          "name": "Acetazolamide",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vincent Kan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2018-03-23",
      "completion_date": "2018-04-04",
      "has_results": true,
      "last_update_posted_date": "2019-05-10",
      "last_synced_at": "2026-05-22T05:46:52.868Z",
      "location_count": 1,
      "location_summary": "Worcester, Massachusetts",
      "locations": [
        {
          "city": "Worcester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03490916"
    },
    {
      "nct_id": "NCT03851744",
      "title": "High Altitude and Exogenous Carbohydrate Oxidation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Glucose Metabolism",
        "High Altitude"
      ],
      "interventions": [
        {
          "name": "Sea Level",
          "type": "OTHER"
        },
        {
          "name": "High Altitude",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "United States Army Research Institute of Environmental Medicine",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "MALE",
        "summary": "18 Years to 39 Years · Male only"
      },
      "enrollment_count": 10,
      "start_date": "2018-11-28",
      "completion_date": "2020-09-01",
      "has_results": true,
      "last_update_posted_date": "2021-09-02",
      "last_synced_at": "2026-05-22T05:46:52.868Z",
      "location_count": 1,
      "location_summary": "Natick, Massachusetts",
      "locations": [
        {
          "city": "Natick",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03851744"
    },
    {
      "nct_id": "NCT05300477",
      "title": "Pharmacological Countermeasures for High Altitude",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hypobaric Hypoxia"
      ],
      "interventions": [
        {
          "name": "Acetazolamide",
          "type": "DRUG"
        },
        {
          "name": "Erythropoietin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "United States Army Research Institute of Environmental Medicine",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 18,
      "start_date": "2022-05-27",
      "completion_date": "2025-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-03-26",
      "last_synced_at": "2026-05-22T05:46:52.868Z",
      "location_count": 1,
      "location_summary": "Natick, Massachusetts",
      "locations": [
        {
          "city": "Natick",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05300477"
    },
    {
      "nct_id": "NCT07216755",
      "title": "Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Adults",
        "Mechanical Ventilation Dependence",
        "Hypoxia",
        "Exercise Training",
        "Exercise Intolerance",
        "Dietary Supplement",
        "Nitrate Supplementation",
        "Inspiratory Muscle Training"
      ],
      "interventions": [
        {
          "name": "Respiratory Muscle Training (RMT)",
          "type": "DEVICE"
        },
        {
          "name": "Sham Respiratory Muscle Training",
          "type": "DEVICE"
        },
        {
          "name": "Dietary Supplement: Beetroot Juice Concentrate",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "placebo beverage",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Embry-Riddle Aeronautical University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 80,
      "start_date": "2025-09-01",
      "completion_date": "2028-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-15",
      "last_synced_at": "2026-05-22T05:46:52.868Z",
      "location_count": 1,
      "location_summary": "Daytona Beach, Florida",
      "locations": [
        {
          "city": "Daytona Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07216755"
    },
    {
      "nct_id": "NCT01902758",
      "title": "Drug Combination on Exercise Performance at High Altitude",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Acute Mountain Sickness"
      ],
      "interventions": [
        {
          "name": "ambrisentan and theophylline",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Montana",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "MALE",
        "summary": "18 Years to 45 Years · Male only"
      },
      "enrollment_count": 28,
      "start_date": "2013-08",
      "completion_date": "2013-08",
      "has_results": true,
      "last_update_posted_date": "2016-02-26",
      "last_synced_at": "2026-05-22T05:46:52.868Z",
      "location_count": 1,
      "location_summary": "Missoula, Montana",
      "locations": [
        {
          "city": "Missoula",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01902758"
    },
    {
      "nct_id": "NCT04567550",
      "title": "RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Diabetic Retinopathy (DR) With and Without Center Involved-Diabetic Macular Edema (CI-DME)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetic Retinopathy (DR)",
        "Center-Involved Diabetic Macular Edema (CI-DME)"
      ],
      "interventions": [
        {
          "name": "ABBV-RGX-314 Dose 1",
          "type": "GENETIC"
        },
        {
          "name": "ABBV-RGX-314 Dose 2",
          "type": "GENETIC"
        },
        {
          "name": "ABBV-RGX-314 Dose 3",
          "type": "GENETIC"
        },
        {
          "name": "Topical Steroid",
          "type": "DRUG"
        },
        {
          "name": "ABBV-RGX-314 Dose 4",
          "type": "GENETIC"
        },
        {
          "name": "Aflibercept",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "GENETIC",
        "DRUG",
        "BIOLOGICAL"
      ],
      "sponsor": "AbbVie",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "25 Years to 89 Years"
      },
      "enrollment_count": 139,
      "start_date": "2020-11-20",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-09-17",
      "last_synced_at": "2026-05-22T05:46:52.868Z",
      "location_count": 25,
      "location_summary": "Phoenix, Arizona • Bakersfield, California • Beverly Hills, California + 21 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Bakersfield",
          "state": "California"
        },
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Campbell",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04567550"
    },
    {
      "nct_id": "NCT02604173",
      "title": "Altitude Sickness Prevention and Efficacy of Comparative Treatments",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Acute Mountain Sickness"
      ],
      "interventions": [
        {
          "name": "Budesonide",
          "type": "DRUG"
        },
        {
          "name": "Acetazolamide",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 103,
      "start_date": "2016-08",
      "completion_date": "2016-09",
      "has_results": true,
      "last_update_posted_date": "2018-12-12",
      "last_synced_at": "2026-05-22T05:46:52.868Z",
      "location_count": 1,
      "location_summary": "Bishop, California",
      "locations": [
        {
          "city": "Bishop",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02604173"
    }
  ]
}