{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Alzheimer%27s+Disease&page=17&q=early+Alzheimer",
    "query": {
      "q": "early Alzheimer",
      "condition": "Alzheimer's Disease",
      "page": 17
    },
    "page_size": 10
  },
  "pagination": {
    "page": 17,
    "page_size": 10,
    "total_count": 388,
    "total_pages": 39,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Alzheimer%27s+Disease&page=18&q=early+Alzheimer&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Alzheimer%27s+Disease&page=16&q=early+Alzheimer&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-14T03:38:03.603Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06566170",
      "title": "A Real-World Comparative Study of Donanemab (LY3002813) Plus Usual Care Versus Usual Care Alone in US Participants With Early Symptomatic Alzheimer's Disease",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Donanemab",
          "type": "DRUG"
        },
        {
          "name": "Usual Care",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eli Lilly and Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 6250,
      "start_date": "2024-10-07",
      "completion_date": "2033-02",
      "has_results": false,
      "last_update_posted_date": "2025-10-09",
      "last_synced_at": "2026-10-14T03:38:03.603Z",
      "location_count": 1,
      "location_summary": "Huntsville, Alabama",
      "locations": [
        {
          "city": "Huntsville",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06566170"
    },
    {
      "nct_id": "NCT07764146",
      "title": "An Open Label Dose Escalation Study of VY1706 in Participants With Early Alzheimer's Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Alzheimer s Disease"
      ],
      "interventions": [
        {
          "name": "VY1706 Low dose",
          "type": "DRUG"
        },
        {
          "name": "VY1706 Mid dose",
          "type": "DRUG"
        },
        {
          "name": "VY1706 High Dose",
          "type": "DRUG"
        },
        {
          "name": "Anti-AAV9 Total Antibody (TAb) Assay",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Voyager Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "30 Years to 80 Years"
      },
      "enrollment_count": 18,
      "start_date": "2026-09-03",
      "completion_date": "2029-04-28",
      "has_results": false,
      "last_update_posted_date": "2026-09-04",
      "last_synced_at": "2026-10-14T03:38:03.603Z",
      "location_count": 1,
      "location_summary": "Maitland, Florida",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07764146"
    },
    {
      "nct_id": "NCT03287765",
      "title": "Evaluating the Relationship Between Tau PET Imaging and CSF Biomarkers of AD (Alzheimer Disease) in Humans",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "18F-AV-1451",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tammie L. S. Benzinger, MD, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 54,
      "start_date": "2016-05",
      "completion_date": "2021-07-19",
      "has_results": false,
      "last_update_posted_date": "2023-05-08",
      "last_synced_at": "2026-10-14T03:38:03.603Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03287765"
    },
    {
      "nct_id": "NCT00329706",
      "title": "Metabolic Cerebral Imaging in Incipient Dementia (MCI-ID)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dementia"
      ],
      "interventions": [
        {
          "name": "FDG-PET brain scan",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 710,
      "start_date": "2006-06",
      "completion_date": "2017-01",
      "has_results": false,
      "last_update_posted_date": "2017-05-02",
      "last_synced_at": "2026-10-14T03:38:03.603Z",
      "location_count": 9,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Santa Monica, California + 5 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00329706"
    },
    {
      "nct_id": "NCT06597058",
      "title": "Phase 2 Estimation Study of Fixed Dose Drugs Combination Type of Polypill",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "MAR",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Noah Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "50 Years to 85 Years"
      },
      "enrollment_count": 121,
      "start_date": "2024-10-16",
      "completion_date": "2025-12-15",
      "has_results": false,
      "last_update_posted_date": "2026-04-08",
      "last_synced_at": "2026-10-14T03:38:03.603Z",
      "location_count": 16,
      "location_summary": "Scottsdale, Arizona • Huntington Beach, California • DeLand, Florida + 11 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Huntington Beach",
          "state": "California"
        },
        {
          "city": "DeLand",
          "state": "Florida"
        },
        {
          "city": "Jupiter",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06597058"
    },
    {
      "nct_id": "NCT04820335",
      "title": "Promoting Independence With Compensatory Cognitive Rehabilitation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Cognitive Impairment",
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Structured External Memory Aid Treatment (SEMAT)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Delaware",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "60 Years to 90 Years"
      },
      "enrollment_count": 68,
      "start_date": "2022-02-01",
      "completion_date": "2025-09-15",
      "has_results": false,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-10-14T03:38:03.603Z",
      "location_count": 1,
      "location_summary": "Newark, Delaware",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04820335"
    },
    {
      "nct_id": "NCT03098459",
      "title": "Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Delirium",
        "Cognitive Impairment",
        "Alzheimer; Early Onset",
        "Trauma",
        "Polytrauma",
        "Traumatic Brain Injury",
        "ICU",
        "Critical Illness"
      ],
      "interventions": [
        {
          "name": "Non-interventional observational prospective cohort study",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 432,
      "start_date": "2017-11-02",
      "completion_date": "2027-10",
      "has_results": false,
      "last_update_posted_date": "2026-01-13",
      "last_synced_at": "2026-10-14T03:38:03.603Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03098459"
    },
    {
      "nct_id": "NCT05894954",
      "title": "Precision Medicine Approach for Early Dementia & Mild Cognitive Impairment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Mild Cognitive Impairment",
        "Dementia, Mild"
      ],
      "interventions": [
        {
          "name": "Precision Medicine Approach",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Hormones and Medications tailored to lab tests, combined with devices that support stress management and brain exercises",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Standard-of-Care",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Lifestyle including diet, exercise, stress management",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "COMBINATION_PRODUCT",
        "BEHAVIORAL"
      ],
      "sponsor": "Alzheimer's Prevention and Reversal Project, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "76 Years",
        "sex": "ALL",
        "summary": "45 Years to 76 Years"
      },
      "enrollment_count": 73,
      "start_date": "2023-07-31",
      "completion_date": "2026-02-09",
      "has_results": false,
      "last_update_posted_date": "2026-02-18",
      "last_synced_at": "2026-10-14T03:38:03.603Z",
      "location_count": 6,
      "location_summary": "Folsom, California • San Rafael, California • Walnut Creek, California + 3 more",
      "locations": [
        {
          "city": "Folsom",
          "state": "California"
        },
        {
          "city": "San Rafael",
          "state": "California"
        },
        {
          "city": "Walnut Creek",
          "state": "California"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Rocky River",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05894954"
    },
    {
      "nct_id": "NCT05827094",
      "title": "Pilot Mobile for Dementia and Frailty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dementia",
        "Frailty"
      ],
      "interventions": [
        {
          "name": "Mobile app",
          "type": "OTHER"
        },
        {
          "name": "Usual Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 19,
      "start_date": "2023-06-06",
      "completion_date": "2024-03-15",
      "has_results": true,
      "last_update_posted_date": "2025-03-13",
      "last_synced_at": "2026-10-14T03:38:03.603Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05827094"
    },
    {
      "nct_id": "NCT05477056",
      "title": "Quality Improvement PrecivityAD Clinician Survey (QUIP I)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer Disease",
        "Mild Cognitive Impairment",
        "Dementia",
        "Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "PrecivityAD blood test",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "C2N Diagnostics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 366,
      "start_date": "2021-03-01",
      "completion_date": "2022-10-06",
      "has_results": false,
      "last_update_posted_date": "2025-02-20",
      "last_synced_at": "2026-10-14T03:38:03.603Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05477056"
    }
  ]
}