{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Alzheimer%27s+Disease&page=2&q=prodromal", "query": { "q": "prodromal", "condition": "Alzheimer's Disease", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 43, "total_pages": 5, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Alzheimer%27s+Disease&page=3&q=prodromal&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Alzheimer%27s+Disease&page=1&q=prodromal&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-11T17:08:11.693Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01224106", "title": "A Study of Gantenerumab in Participants With Prodromal Alzheimer's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Alzheimer's Disease" ], "interventions": [ { "name": "Gantenerumab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Hoffmann-La Roche", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "50 Years to 85 Years" }, "enrollment_count": 799, "start_date": "2010-11-30", "completion_date": "2020-09-10", "has_results": true, "last_update_posted_date": "2021-12-13", "last_synced_at": "2026-10-11T17:08:11.693Z", "location_count": 24, "location_summary": "Phoenix, Arizona • La Jolla, California • New Haven, Connecticut + 21 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "La Jolla", "state": "California" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "Delray Beach", "state": "Florida" }, { "city": "Hollywood", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01224106" }, { "nct_id": "NCT02956486", "title": "A 24-Month Study to Evaluate the Efficacy and Safety of Elenbecestat (E2609) in Participants With Early Alzheimer's Disease", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Alzheimer's Disease" ], "interventions": [ { "name": "Elenbecestat", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eisai Co., Ltd.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "50 Years to 85 Years" }, "enrollment_count": 2212, "start_date": "2016-10-20", "completion_date": "2020-01-15", "has_results": true, "last_update_posted_date": "2021-02-03", "last_synced_at": "2026-10-11T17:08:11.693Z", "location_count": 88, "location_summary": "Chandler, Arizona • Colton, California • Costa Mesa, California + 68 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Colton", "state": "California" }, { "city": "Costa Mesa", "state": "California" }, { "city": "Fullerton", "state": "California" }, { "city": "Imperial", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02956486" }, { "nct_id": "NCT04937959", "title": "Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping - PAST Extension", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Alzheimer Disease", "Alzheimer's Disease (Incl Subtypes)", "Preclinical Alzheimer's Disease", "Prodromal Alzheimer's Disease", "Mild Cognitive Impairment", "Normal Cognition" ], "interventions": [], "intervention_types": [], "sponsor": "Novoic Limited", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "50 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "50 Years to 85 Years" }, "enrollment_count": 40, "start_date": "2021-01-22", "completion_date": "2022-08-30", "has_results": false, "last_update_posted_date": "2022-04-07", "last_synced_at": "2026-10-11T17:08:11.693Z", "location_count": 1, "location_summary": "Santa Ana, California", "locations": [ { "city": "Santa Ana", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04937959" }, { "nct_id": "NCT04029623", "title": "Partnered Rhythmic Rehabilitation in Prodromal Alzheimer's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Prodromal Alzheimer's Disease" ], "interventions": [ { "name": "Partnered Rhythmic Rehabilitation (PRR)", "type": "OTHER" }, { "name": "Group walking (WALK)", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "50 Years to 80 Years" }, "enrollment_count": 76, "start_date": "2019-10-29", "completion_date": "2025-09-16", "has_results": false, "last_update_posted_date": "2026-05-26", "last_synced_at": "2026-10-11T17:08:11.693Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT04029623" }, { "nct_id": "NCT02640092", "title": "Longitudinal Evaluation of [18F]GTP1 as a PET Radioligand for Imaging Tau in the Brain of Participants With Alzheimer's Disease Compared to Healthy Participants", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Alzheimer's Disease" ], "interventions": [ { "name": "[18F]GTP1", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Genentech, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "50 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "50 Years to 85 Years" }, "enrollment_count": 72, "start_date": "2015-12-23", "completion_date": "2019-06-11", "has_results": false, "last_update_posted_date": "2019-12-23", "last_synced_at": "2026-10-11T17:08:11.693Z", "location_count": 16, "location_summary": "New Haven, Connecticut • Stamford, Connecticut • Fort Myers, Florida + 13 more", "locations": [ { "city": "New Haven", "state": "Connecticut" }, { "city": "Stamford", "state": "Connecticut" }, { "city": "Fort Myers", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Orlando", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02640092" }, { "nct_id": "NCT02547818", "title": "Safety and Efficacy Study of ALZT-OP1 in Subjects With Evidence of Early Alzheimer's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Alzheimer's Disease" ], "interventions": [ { "name": "ALZT-OP1a", "type": "DRUG" }, { "name": "ALZT-OP1b", "type": "DRUG" }, { "name": "Placebo ALZT-OP1a", "type": "OTHER" }, { "name": "Placebo ALZT-OP1b", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "AZTherapies, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "55 Years", "maximum_age": "79 Years", "sex": "ALL", "summary": "55 Years to 79 Years" }, "enrollment_count": 620, "start_date": "2015-09-15", "completion_date": "2020-11-18", "has_results": false, "last_update_posted_date": "2021-11-10", "last_synced_at": "2026-10-11T17:08:11.693Z", "location_count": 69, "location_summary": "Gilbert, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 56 more", "locations": [ { "city": "Gilbert", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Laguna Hills", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02547818" }, { "nct_id": "NCT05479552", "title": "A Diagnostic Test for Dementia With Lewy Bodies", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "MCI-AD, Early Stage Alzheimer's Disease", "MCI-DLB, Early Stage Dementia With Lewy Bodies" ], "interventions": [ { "name": "Syn-One Test", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "CND Life Sciences", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "50 Years to 85 Years" }, "enrollment_count": 80, "start_date": "2022-08-15", "completion_date": "2025-10-31", "has_results": false, "last_update_posted_date": "2025-01-15", "last_synced_at": "2026-10-11T17:08:11.693Z", "location_count": 12, "location_summary": "Scottsdale, Arizona • La Jolla, California • Englewood, Colorado + 8 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "La Jolla", "state": "California" }, { "city": "Englewood", "state": "Colorado" }, { "city": "Boca Raton", "state": "Florida" }, { "city": "Winter Park", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05479552" }, { "nct_id": "NCT06956300", "title": "TMS for Cognitive Decline in Aging and Preclinical AD", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Prodromal Alzheimer's Disease", "Preclinical Alzheimer's Disease", "Healthy Aging", "Cognitive Decline" ], "interventions": [ { "name": "Active rTMS", "type": "DEVICE" }, { "name": "Sham rTMS", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "40 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "40 Years to 99 Years" }, "enrollment_count": 80, "start_date": "2025-04-07", "completion_date": "2029-08-31", "has_results": false, "last_update_posted_date": "2026-02-20", "last_synced_at": "2026-10-11T17:08:11.693Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT06956300" }, { "nct_id": "NCT05019014", "title": "Olfactory Deficits in Neurologic Disease", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Alzheimer Disease", "Traumatic Brain Injury", "Amyotrophic Lateral Sclerosis", "Frontotemporal Dementia", "Lewy Body Disease", "Mild Cognitive Impairment" ], "interventions": [], "intervention_types": [], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 201, "start_date": "2011-08-10", "completion_date": "2020-07-03", "has_results": false, "last_update_posted_date": "2021-08-24", "last_synced_at": "2026-10-11T17:08:11.693Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05019014" }, { "nct_id": "NCT01727622", "title": "Arterial Spin Labeling (ASL) MRI for Cognitive Decline", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Mild Cognitive Impairment", "Alzheimer's Disease" ], "interventions": [ { "name": "FDG-PET", "type": "DRUG" }, { "name": "ASL-MRI", "type": "OTHER" }, { "name": "Lumbar Puncture", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "OTHER", "PROCEDURE" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "55 Years", "maximum_age": "89 Years", "sex": "ALL", "summary": "55 Years to 89 Years" }, "enrollment_count": 102, "start_date": "2012-08", "completion_date": "2018-05-31", "has_results": false, "last_update_posted_date": "2020-09-28", "last_synced_at": "2026-10-11T17:08:11.693Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01727622" } ] }