{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Alzheimer%27s+Disease+or+Vascular+Dementia",
    "query": {
      "condition": "Alzheimer's Disease or Vascular Dementia"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T11:35:33.489Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00056524",
      "title": "Safety Study of AVP-923 in the Treatment of IEED (Involuntary Emotional Expression Disorder) Also Known as Pseudobulbar Affect (Episodes of Uncontrolled Crying and/or Laughter)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Alzheimer's Disease",
        "Stroke",
        "Parkinson's Disease",
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "AVP-923",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Avanir Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 600,
      "start_date": "2003-02",
      "completion_date": "2007-06",
      "has_results": false,
      "last_update_posted_date": "2016-07-14",
      "last_synced_at": "2026-06-26T11:35:33.489Z",
      "location_count": 39,
      "location_summary": "Phoenix, Arizona • La Jolla, California • Los Angeles, California + 31 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Darien",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00056524"
    },
    {
      "nct_id": "NCT02886494",
      "title": "A Study to Evaluate Efficacy and Safety of BAC in Patient With Alzheimer's Disease or Vascular Dementia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Alzheimer's Disease or Vascular Dementia"
      ],
      "interventions": [
        {
          "name": "BAC treatment",
          "type": "DRUG"
        },
        {
          "name": "Matched vehicle",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Charsire Biotechnology Corp.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2016-12",
      "completion_date": "2018-11-01",
      "has_results": true,
      "last_update_posted_date": "2022-10-13",
      "last_synced_at": "2026-06-26T11:35:33.489Z",
      "location_count": 10,
      "location_summary": "Tempe, Arizona • Little Rock, Arkansas • Rogers, Arkansas + 7 more",
      "locations": [
        {
          "city": "Tempe",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Rogers",
          "state": "Arkansas"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02886494"
    },
    {
      "nct_id": "NCT03724136",
      "title": "Alzheimer's Autism and Cognitive Impairment Stem Cell Treatment Study",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease",
        "Alzheimer Dementia",
        "Vascular Dementia",
        "Lewy Body Disease",
        "Lewy Body Dementia With Behavioral Disturbance (Disorder)",
        "Dementia, Mixed",
        "Parkinson-Dementia Syndrome",
        "Chronic Traumatic Encephalopathy",
        "Huntington's Dementia",
        "Wernicke Korsakoff Syndrome",
        "Traumatic Brain Injury",
        "Dementia, Multi-Infarct",
        "Autism",
        "Autism Spectrum Disorder",
        "Autistic Behavior",
        "Autistic Disorder, Current or Active State",
        "Cadasil",
        "LATE Limbic-predominant Age-related TDP-43 Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Intravenous Bone Marrow Stem Cell (BMSC) Fraction",
          "type": "PROCEDURE"
        },
        {
          "name": "Intranasal Topical Bone Marrow Stem Cell (BMSC) Fraction",
          "type": "PROCEDURE"
        },
        {
          "name": "Near Infrared Light",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "MD Stem Cells",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2018-10-24",
      "completion_date": "2025-07-31",
      "has_results": false,
      "last_update_posted_date": "2024-04-15",
      "last_synced_at": "2026-06-26T11:35:33.489Z",
      "location_count": 2,
      "location_summary": "Westport, Connecticut • Coral Springs, Florida",
      "locations": [
        {
          "city": "Westport",
          "state": "Connecticut"
        },
        {
          "city": "Coral Springs",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03724136"
    },
    {
      "nct_id": "NCT07392723",
      "title": "ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cognitive Dysfunction",
        "Alzheimer Disease",
        "Blood-Brain Barrier",
        "Apolipoprotein E, Deficiency or Defect of",
        "Brain Aging",
        "Fatty Acids, Omega-3"
      ],
      "interventions": [
        {
          "name": "Alpha-Linolenic Acid (2.6 g/day)",
          "type": "DRUG"
        },
        {
          "name": "Placebo Control Group",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Michal Schnaider Beeri, Ph.D.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2025-01-12",
      "completion_date": "2027-10",
      "has_results": false,
      "last_update_posted_date": "2026-02-06",
      "last_synced_at": "2026-06-26T11:35:33.489Z",
      "location_count": 1,
      "location_summary": "New Brunswick, New Jersey",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07392723"
    },
    {
      "nct_id": "NCT05635266",
      "title": "Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Age-Related Macular Degeneration",
        "Allergies",
        "Alpha-Gal Syndrome",
        "Alzheimer Disease",
        "Amyloidosis",
        "Ankylosing Spondylitis",
        "Arthritis",
        "Alopecia Areata",
        "Asthma",
        "Atopic Dermatitis",
        "Autism",
        "Autoimmune Hepatitis",
        "Behcet's Disease",
        "Beta-Thalassemia",
        "Cancer",
        "Celiac Disease",
        "Kidney Diseases",
        "COPD",
        "Crohn Disease",
        "Cystic Fibrosis",
        "Diabetes",
        "Dravet Syndrome",
        "DMD",
        "Fibromyalgia",
        "Graves Disease",
        "Thyroid Diseases",
        "Hepatitis",
        "Hidradenitis Suppurativa",
        "ITP",
        "Leukemia",
        "ALS",
        "Lupus or SLE",
        "Lymphoma",
        "Multiple Sclerosis",
        "Myasthenia Gravis",
        "Heart Diseases",
        "Parkinson Disease",
        "Pemphigus Vulgaris",
        "Cirrhosis",
        "Psoriasis",
        "Schizophrenia",
        "Scleroderma",
        "Sickle Cell Disease",
        "Stroke",
        "Ulcerative Colitis",
        "Vasculitis",
        "Vitiligo"
      ],
      "interventions": [
        {
          "name": "Specimen sample",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Sanguine Biosciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 20000,
      "start_date": "2021-10-26",
      "completion_date": "2025-10",
      "has_results": false,
      "last_update_posted_date": "2024-05-07",
      "last_synced_at": "2026-06-26T11:35:33.489Z",
      "location_count": 1,
      "location_summary": "Waltham, Massachusetts",
      "locations": [
        {
          "city": "Waltham",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05635266"
    },
    {
      "nct_id": "NCT05734638",
      "title": "Stress and Blood Pressure Management for Caregivers",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension",
        "Stress, Psychological"
      ],
      "interventions": [
        {
          "name": "MIM-DASH",
          "type": "BEHAVIORAL"
        },
        {
          "name": "MIM Only",
          "type": "BEHAVIORAL"
        },
        {
          "name": "DASH Only",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "40 Years and older · Female only"
      },
      "enrollment_count": 90,
      "start_date": "2023-09-11",
      "completion_date": "2026-07-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-23",
      "last_synced_at": "2026-06-26T11:35:33.489Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05734638"
    },
    {
      "nct_id": "NCT00597376",
      "title": "Study of the Effects of Cerefolin NAC on Inflammation Blood Markers in Older Individuals With Memory Complaints",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Subjective Memory Loss in Older Persons"
      ],
      "interventions": [
        {
          "name": "Cerefolin NAC (a medical food)",
          "type": "OTHER"
        },
        {
          "name": "Cerefolin NAC placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 104,
      "start_date": "2007-11",
      "completion_date": "2011-05",
      "has_results": true,
      "last_update_posted_date": "2013-05-23",
      "last_synced_at": "2026-06-26T11:35:33.489Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00597376"
    }
  ]
}