{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Alzheimer+Disease+2&page=4",
    "query": {
      "condition": "Alzheimer Disease 2",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 152,
    "total_pages": 16,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Alzheimer+Disease+2&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Alzheimer+Disease+2&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-09T14:32:00.319Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02246075",
      "title": "Study of the Safety of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease Currently Receiving Memantine",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Alzheimer's Disease",
        "Dementia",
        "Cognition"
      ],
      "interventions": [
        {
          "name": "EVP-6124",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "FORUM Pharmaceuticals Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "55 Years to 85 Years"
      },
      "enrollment_count": 0,
      "start_date": "2015-07",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2015-10-15",
      "last_synced_at": "2026-10-09T14:32:00.319Z",
      "location_count": 2,
      "location_summary": "Delray Beach, Florida • Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Delray Beach",
          "state": "Florida"
        },
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02246075"
    },
    {
      "nct_id": "NCT01224106",
      "title": "A Study of Gantenerumab in Participants With Prodromal Alzheimer's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "Gantenerumab",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hoffmann-La Roche",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "50 Years to 85 Years"
      },
      "enrollment_count": 799,
      "start_date": "2010-11-30",
      "completion_date": "2020-09-10",
      "has_results": true,
      "last_update_posted_date": "2021-12-13",
      "last_synced_at": "2026-10-09T14:32:00.319Z",
      "location_count": 24,
      "location_summary": "Phoenix, Arizona • La Jolla, California • New Haven, Connecticut + 21 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Delray Beach",
          "state": "Florida"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01224106"
    },
    {
      "nct_id": "NCT03823404",
      "title": "GAIN Trial: Phase 2/3 Study of COR388 in Subjects With Alzheimer's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "COR388 capsule",
          "type": "DRUG"
        },
        {
          "name": "Placebo capsule",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cortexyme Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "55 Years to 80 Years"
      },
      "enrollment_count": 643,
      "start_date": "2019-03-28",
      "completion_date": "2022-01-01",
      "has_results": true,
      "last_update_posted_date": "2023-02-23",
      "last_synced_at": "2026-10-09T14:32:00.319Z",
      "location_count": 58,
      "location_summary": "Phoenix, Arizona • Sun City, Arizona • Costa Mesa, California + 48 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Sun City",
          "state": "Arizona"
        },
        {
          "city": "Costa Mesa",
          "state": "California"
        },
        {
          "city": "Long Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03823404"
    },
    {
      "nct_id": "NCT02346201",
      "title": "Apathy in Dementia Methylphenidate Trial 2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Apathy",
        "Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "Methylphenidate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins Bloomberg School of Public Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 200,
      "start_date": "2016-01",
      "completion_date": "2020-07-15",
      "has_results": true,
      "last_update_posted_date": "2023-06-13",
      "last_synced_at": "2026-10-09T14:32:00.319Z",
      "location_count": 9,
      "location_summary": "Phoenix, Arizona • Little Rock, Arkansas • New Haven, Connecticut + 6 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02346201"
    },
    {
      "nct_id": "NCT03534687",
      "title": "Exercise and the Receptor for Advanced Glycation End Products (RAGE)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 2"
      ],
      "interventions": [
        {
          "name": "Aerobic Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "40 Years to 75 Years"
      },
      "enrollment_count": 50,
      "start_date": "2018-12-20",
      "completion_date": "2023-05-08",
      "has_results": true,
      "last_update_posted_date": "2024-08-13",
      "last_synced_at": "2026-10-09T14:32:00.319Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03534687"
    },
    {
      "nct_id": "NCT04049643",
      "title": "Hearing Aid and Individuals With Cognitive Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Presbycusis, Bilateral",
        "Alzheimer Disease 2 Due to Apoe4 Isoform",
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Audiologist-based fitting",
          "type": "DEVICE"
        },
        {
          "name": "Service-only Fitting",
          "type": "DEVICE"
        },
        {
          "name": "Device-only fitting",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Yu-Hsiang Wu",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "55 Years to 85 Years"
      },
      "enrollment_count": 17,
      "start_date": "2019-12-01",
      "completion_date": "2024-11-07",
      "has_results": true,
      "last_update_posted_date": "2025-04-17",
      "last_synced_at": "2026-10-09T14:32:00.319Z",
      "location_count": 2,
      "location_summary": "Iowa City, Iowa • Nashville, Tennessee",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04049643"
    },
    {
      "nct_id": "NCT04100889",
      "title": "A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Alzheimer's Disease",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer Disease",
        "Alzheimer Disease 1",
        "Alzheimer Disease 2",
        "Alzheimer Disease 3",
        "Alzheimer Disease 4",
        "Alzheimer Disease 5",
        "Alzheimer Disease 6",
        "Alzheimer Disease 7",
        "Alzheimer Disease 8",
        "Alzheimer Disease 9, Late-Onset",
        "Alzheimer Disease 10",
        "Alzheimer Disease 11",
        "Alzheimer Disease 12",
        "Alzheimer Disease 13",
        "Alzheimer Disease 14",
        "Alzheimer Disease 15",
        "Alzheimer Disease 16",
        "Alzheimer Disease 17",
        "Alzheimer Disease 18",
        "Alzheimer Disease 19",
        "Alzheimer Disease, Early Onset",
        "Alzheimer Disease, Late Onset",
        "Alzheimer Disease Focal"
      ],
      "interventions": [
        {
          "name": "No Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "ProgenaBiome",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2020-03-02",
      "completion_date": "2030-07",
      "has_results": false,
      "last_update_posted_date": "2025-06-05",
      "last_synced_at": "2026-10-09T14:32:00.319Z",
      "location_count": 1,
      "location_summary": "Ventura, California",
      "locations": [
        {
          "city": "Ventura",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04100889"
    },
    {
      "nct_id": "NCT06691256",
      "title": "Preventing Medication Mismanagement in People Living With Dementia Through Automated Medication Dispensing With Facial Recognition and Video Observation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Alzheimer Disease",
        "Dementia",
        "Medication Adherence",
        "Type 2 Diabetes Mellitus (T2DM)"
      ],
      "interventions": [
        {
          "name": "HiDO-ALZ",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "HiDO Technologies",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2024-09-05",
      "completion_date": "2025-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-10-07",
      "last_synced_at": "2026-10-09T14:32:00.319Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06691256"
    },
    {
      "nct_id": "NCT05027789",
      "title": "Brain Boosters 2 in Persons at Risk for Alzheimer's Disease: a Digital Application Supported Intervention",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Memory Disorders",
        "Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Self-Guided",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Structured Group",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "65 Years to 90 Years"
      },
      "enrollment_count": 263,
      "start_date": "2021-08-13",
      "completion_date": "2026-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-08",
      "last_synced_at": "2026-10-09T14:32:00.319Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05027789"
    },
    {
      "nct_id": "NCT05637801",
      "title": "A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (HOPE Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease",
        "Alzheimer Disease 1",
        "Alzheimer Disease 2",
        "Alzheimer Disease 3",
        "Alzheimer Disease, Early Onset",
        "Alzheimer Disease, Late Onset",
        "Alzheimer Disease 9",
        "Alzheimer Disease 4",
        "Alzheimer Disease 7",
        "Alzheimer Disease 17",
        "Alzheimer's Dementia Late Onset",
        "Alzheimer Disease 5",
        "Alzheimer Disease 6",
        "Alzheimer Disease 8",
        "Alzheimer Disease 10",
        "Alzheimer Disease 11",
        "Alzheimer Disease 12",
        "Alzheimer Disease 13",
        "Alzheimer Disease 14",
        "Alzheimer Disease 15",
        "Alzheimer Disease 16",
        "Alzheimer Disease 18",
        "Alzheimer Disease 19",
        "Dementia",
        "Dementia Alzheimers",
        "Dementia, Mild",
        "Dementia of Alzheimer Type",
        "Dementia Moderate",
        "Dementia Senile",
        "Mild Cognitive Impairment",
        "Mild Dementia",
        "MCI",
        "Cognitive Impairment",
        "Cognitive Decline",
        "Cognitive Impairment, Mild"
      ],
      "interventions": [
        {
          "name": "Spectris™ AD - Active",
          "type": "DEVICE"
        },
        {
          "name": "Spectris™ AD - Sham",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cognito Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "50 Years to 90 Years"
      },
      "enrollment_count": 673,
      "start_date": "2022-12-13",
      "completion_date": "2026-08-17",
      "has_results": false,
      "last_update_posted_date": "2026-09-09",
      "last_synced_at": "2026-10-09T14:32:00.319Z",
      "location_count": 68,
      "location_summary": "Gilbert, Arizona • Phoenix, Arizona • Sun City, Arizona + 62 more",
      "locations": [
        {
          "city": "Gilbert",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Sun City",
          "state": "Arizona"
        },
        {
          "city": "Anaheim",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05637801"
    }
  ]
}