{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Alzheimers+Disease%2C+Familial&page=2", "query": { "condition": "Alzheimers Disease, Familial", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Alzheimers+Disease%2C+Familial&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-06-10T20:37:43.862Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06647498", "title": "A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Alzheimers Disease", "Dementia", "Alzheimers Disease, Familial" ], "interventions": [ { "name": "Remternetug", "type": "DRUG" }, { "name": "Matching Placebo (Remternetug)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 280, "start_date": "2024-11-22", "completion_date": "2034-08", "has_results": false, "last_update_posted_date": "2026-02-13", "last_synced_at": "2026-06-10T20:37:43.862Z", "location_count": 12, "location_summary": "Birmingham, Alabama • La Jolla, California • New Haven, Connecticut + 9 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "La Jolla", "state": "California" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Park Ridge", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT06647498" }, { "nct_id": "NCT05916664", "title": "Efficacy Study of Kinto Care Coaching for Dementia Family Caregivers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dementia", "Alzheimer Disease", "Lewy Body Disease", "Vascular Dementia", "Frontotemporal Dementia", "Mixed Dementia" ], "interventions": [ { "name": "Kinto Care Coaching", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Kinto", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 495, "start_date": "2023-05-18", "completion_date": "2024-04-22", "has_results": true, "last_update_posted_date": "2025-03-05", "last_synced_at": "2026-06-10T20:37:43.862Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT05916664" }, { "nct_id": "NCT05776641", "title": "Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People At Risk for Alzheimer's Disease", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Alzheimer Disease", "Family Members" ], "interventions": [ { "name": "GENUS", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "55 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "55 Years to 90 Years" }, "enrollment_count": 200, "start_date": "2024-01-10", "completion_date": "2026-05", "has_results": false, "last_update_posted_date": "2025-01-10", "last_synced_at": "2026-06-10T20:37:43.862Z", "location_count": 2, "location_summary": "Boston, Massachusetts • Cambridge, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Cambridge", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05776641" }, { "nct_id": "NCT05637801", "title": "A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (HOPE Study)", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Alzheimer Disease", "Alzheimer Disease 1", "Alzheimer Disease 2", "Alzheimer Disease 3", "Alzheimer Disease, Early Onset", "Alzheimer Disease, Late Onset", "Alzheimer Disease 9", "Alzheimer Disease 4", "Alzheimer Disease 7", "Alzheimer Disease 17", "Alzheimer's Dementia Late Onset", "Alzheimer Disease 5", "Alzheimer Disease 6", "Alzheimer Disease 8", "Alzheimer Disease 10", "Alzheimer Disease 11", "Alzheimer Disease 12", "Alzheimer Disease 13", "Alzheimer Disease 14", "Alzheimer Disease 15", "Alzheimer Disease 16", "Alzheimer Disease 18", "Alzheimer Disease 19", "Dementia", "Dementia Alzheimers", "Dementia, Mild", "Dementia of Alzheimer Type", "Dementia Moderate", "Dementia Senile", "Mild Cognitive Impairment", "Mild Dementia", "MCI", "Cognitive Impairment", "Cognitive Decline", "Cognitive Impairment, Mild" ], "interventions": [ { "name": "Spectris™ AD - Active", "type": "DEVICE" }, { "name": "Spectris™ AD - Sham", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Cognito Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "50 Years to 90 Years" }, "enrollment_count": 670, "start_date": "2022-12-13", "completion_date": "2026-07", "has_results": false, "last_update_posted_date": "2026-05-05", "last_synced_at": "2026-06-10T20:37:43.862Z", "location_count": 68, "location_summary": "Gilbert, Arizona • Phoenix, Arizona • Sun City, Arizona + 62 more", "locations": [ { "city": "Gilbert", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Sun City", "state": "Arizona" }, { "city": "Anaheim", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05637801" }, { "nct_id": "NCT03431896", "title": "Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Amyloidosis", "Amyloid", "Amyloid Neuropathies, Familial", "Amyloid Cardiomyopathy", "Amyloid - Primary", "Transthyretin Amyloidosis", "AL Amyloidosis" ], "interventions": [], "intervention_types": [], "sponsor": "The Cleveland Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 37, "start_date": "2018-02-01", "completion_date": "2026-03-09", "has_results": false, "last_update_posted_date": "2026-03-12", "last_synced_at": "2026-06-10T20:37:43.862Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT03431896" }, { "nct_id": "NCT04715399", "title": "UPenn Observational Research Repository on Neurodegenerative Disease", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Frontotemporal Degeneration(FTD)", "Primary Progressive Aphasia(PPA)", "Familial Frontotemporal Lobar Degeneration (fFTLD)", "Amyotrophic Lateral Sclerosis(ALS)", "Lewy Body Disease(LBD)", "Progressive Supranuclear Palsy(PSP)", "Corticobasal Syndrome(CBS)", "Posterior Cortical Atrophy(PCA)", "Alzheimer's Disease(AD)" ], "interventions": [ { "name": "No intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1000, "start_date": "2020-05-29", "completion_date": "2070-05-30", "has_results": false, "last_update_posted_date": "2026-01-22", "last_synced_at": "2026-06-10T20:37:43.862Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT04715399" }, { "nct_id": "NCT05465109", "title": "Traumatic Brain Injury and Alzheimer's Disease/Related Dementias Caregiver Support Intervention", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Caregiver Burden", "Caregiver Stress Syndrome", "Caregiver Burnout" ], "interventions": [ { "name": "TBI-AD/ADRD Caregiver Support Intervention (TACSI)", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 95, "start_date": "2022-07-01", "completion_date": "2025-06-28", "has_results": false, "last_update_posted_date": "2025-12-22", "last_synced_at": "2026-06-10T20:37:43.862Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT05465109" }, { "nct_id": "NCT04100889", "title": "A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Alzheimer's Disease", "overall_status": "WITHDRAWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Alzheimer Disease", "Alzheimer Disease 1", "Alzheimer Disease 2", "Alzheimer Disease 3", "Alzheimer Disease 4", "Alzheimer Disease 5", "Alzheimer Disease 6", "Alzheimer Disease 7", "Alzheimer Disease 8", "Alzheimer Disease 9, Late-Onset", "Alzheimer Disease 10", "Alzheimer Disease 11", "Alzheimer Disease 12", "Alzheimer Disease 13", "Alzheimer Disease 14", "Alzheimer Disease 15", "Alzheimer Disease 16", "Alzheimer Disease 17", "Alzheimer Disease 18", "Alzheimer Disease 19", "Alzheimer Disease, Early Onset", "Alzheimer Disease, Late Onset", "Alzheimer Disease Focal" ], "interventions": [ { "name": "No Intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "ProgenaBiome", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2020-03-02", "completion_date": "2030-07", "has_results": false, "last_update_posted_date": "2025-06-05", "last_synced_at": "2026-06-10T20:37:43.862Z", "location_count": 1, "location_summary": "Ventura, California", "locations": [ { "city": "Ventura", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04100889" }, { "nct_id": "NCT05942040", "title": "Translating Data Science to Palliative Care", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Alzheimer's Disease and Related Dementias" ], "interventions": [ { "name": "Tailored Palliative Care Information", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Rutgers, The State University of New Jersey", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 301, "start_date": "2024-02-15", "completion_date": "2024-09-30", "has_results": true, "last_update_posted_date": "2025-11-18", "last_synced_at": "2026-06-10T20:37:43.862Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05942040" }, { "nct_id": "NCT04103580", "title": "Caregiver Speaks: A Technologically Mediated Storytelling Intervention", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Alzheimer Disease" ], "interventions": [ { "name": "Photo elicitation", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 457, "start_date": "2020-03-01", "completion_date": "2023-08-31", "has_results": true, "last_update_posted_date": "2025-02-26", "last_synced_at": "2026-06-10T20:37:43.862Z", "location_count": 1, "location_summary": "Columbia, Missouri", "locations": [ { "city": "Columbia", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT04103580" } ] }