{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Amputation%2C+Surgical",
    "query": {
      "condition": "Amputation, Surgical"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 28,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Amputation%2C+Surgical&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T04:50:53.561Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06071715",
      "title": "Cryoanalgesia to Treat Phantom Limb Pain Following Above-Knee Amputation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation, Surgical",
        "Amputation, Traumatic",
        "Phantom Limb Pain",
        "Phantom Pain Following Amputation of Lower Limb"
      ],
      "interventions": [
        {
          "name": "ACTIVE cryoneurolysis",
          "type": "DEVICE"
        },
        {
          "name": "SHAM cryoneurolysis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2024-02-12",
      "completion_date": "2025-10-09",
      "has_results": true,
      "last_update_posted_date": "2026-04-08",
      "last_synced_at": "2026-05-22T04:50:53.561Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06071715"
    },
    {
      "nct_id": "NCT00942890",
      "title": "Strength, Pain and Function in Operation Iraqi Freedom/Operation Enduring Freedom Amputees: A Nurse-Managed Program",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Amputation"
      ],
      "interventions": [
        {
          "name": "NMES (EMPI 300PV stimulator) plus standard of care",
          "type": "DEVICE"
        },
        {
          "name": "TMARP standard of care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Tennessee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 44,
      "start_date": "2009-04",
      "completion_date": "2015-08",
      "has_results": true,
      "last_update_posted_date": "2018-04-10",
      "last_synced_at": "2026-05-22T04:50:53.561Z",
      "location_count": 3,
      "location_summary": "San Diego, California • Bethesda, Maryland • Memphis, Tennessee",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00942890"
    },
    {
      "nct_id": "NCT03351387",
      "title": "Wound Necrosis in Lower Extremity Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Extremity Lower Wounds"
      ],
      "interventions": [
        {
          "name": "SPY Intra-operative Angiography",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2017-10-20",
      "completion_date": "2018-04-18",
      "has_results": false,
      "last_update_posted_date": "2021-12-17",
      "last_synced_at": "2026-05-22T04:50:53.561Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03351387"
    },
    {
      "nct_id": "NCT03461120",
      "title": "Improving Postamputation Functioning by Decreasing Phantom Pain With Perioperative Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Lower Extremity Surgical Amputation",
        "Post-amputation Phantom Limb Pain"
      ],
      "interventions": [
        {
          "name": "Experimental continuous peripheral nerve blocks",
          "type": "DRUG"
        },
        {
          "name": "Control continuous peripheral nerve blocks",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 203,
      "start_date": "2018-03-23",
      "completion_date": "2026-11-18",
      "has_results": false,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-05-22T04:50:53.561Z",
      "location_count": 8,
      "location_summary": "San Diego, California • Boston, Massachusetts • Cleveland, Ohio + 1 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03461120"
    },
    {
      "nct_id": "NCT03250442",
      "title": "Evaluating the Outcomes for Incisional Application of Negative Pressure for Nontraumatic Amputations",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgical Wound",
        "Wound Heal",
        "Amputation"
      ],
      "interventions": [
        {
          "name": "PrevenaTM Device",
          "type": "DEVICE"
        },
        {
          "name": "Standard Dry Dressing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Georgetown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 112,
      "start_date": "2017-11-01",
      "completion_date": "2021-09",
      "has_results": false,
      "last_update_posted_date": "2019-09-25",
      "last_synced_at": "2026-05-22T04:50:53.561Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03250442"
    },
    {
      "nct_id": "NCT04865679",
      "title": "Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Symptomatic Neuroma",
        "Amputation",
        "Chronic Nerve Pain"
      ],
      "interventions": [
        {
          "name": "Axoguard Nerve Cap®",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Axogen Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 15,
      "start_date": "2022-03-02",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-05-02",
      "last_synced_at": "2026-05-22T04:50:53.561Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Lubbock, Texas",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04865679"
    },
    {
      "nct_id": "NCT02395497",
      "title": "Human Penile Allotransplantation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Amputation",
        "Wounds and Injuries",
        "Amputation, Traumatic",
        "Urologic Surgical Procedures, Male",
        "Amputation, Traumatic/Surgery",
        "Penis/Transplantation",
        "Penis/Surgery",
        "Penis/Injuries",
        "Congenital Anomaly, Male Genitalia"
      ],
      "interventions": [
        {
          "name": "Monoclonal Antibody (Humanized Anti-CD52)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Tacrolimus",
          "type": "DRUG"
        },
        {
          "name": "Penile Allotransplantation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "69 Years",
        "sex": "MALE",
        "summary": "18 Years to 69 Years · Male only"
      },
      "enrollment_count": 60,
      "start_date": "2014-06",
      "completion_date": "2039-06",
      "has_results": false,
      "last_update_posted_date": "2025-07-07",
      "last_synced_at": "2026-05-22T04:50:53.561Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02395497"
    },
    {
      "nct_id": "NCT03787862",
      "title": "Investigation of the Use of Hyperspectral Imaging in Foot Surgery Patients",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Foot Ulcers",
        "Osteomyelitis",
        "Amputation"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2014-06-13",
      "completion_date": "2015-06-13",
      "has_results": false,
      "last_update_posted_date": "2018-12-26",
      "last_synced_at": "2026-05-22T04:50:53.561Z",
      "location_count": 2,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03787862"
    },
    {
      "nct_id": "NCT04204668",
      "title": "Surgical Treatments for Neuroma Pain in Amputees",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain, Neuropathic",
        "Amputation Neuroma",
        "Phantom Limb Pain"
      ],
      "interventions": [
        {
          "name": "TMR",
          "type": "PROCEDURE"
        },
        {
          "name": "RPNI",
          "type": "PROCEDURE"
        },
        {
          "name": "VDMT",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2021-04-01",
      "completion_date": "2025-02-12",
      "has_results": false,
      "last_update_posted_date": "2025-06-03",
      "last_synced_at": "2026-05-22T04:50:53.561Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04204668"
    },
    {
      "nct_id": "NCT05009394",
      "title": "Surgical Treatments for Postamputation Pain",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Residual Limb Pain",
        "Amputation Neuroma",
        "Phantom Limb Pain",
        "Pain, Neuropathic",
        "Pain, Nerve"
      ],
      "interventions": [
        {
          "name": "Targeted Muscle Reinnervation (TMR)",
          "type": "PROCEDURE"
        },
        {
          "name": "Regenerative Peripheral Nerve Interface (RPNI)",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard neuroma treatment, neuroma excision, and muscle burying",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Prometei Pain Rehabilitation Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2023-06-20",
      "completion_date": "2029-06",
      "has_results": false,
      "last_update_posted_date": "2025-01-09",
      "last_synced_at": "2026-05-22T04:50:53.561Z",
      "location_count": 3,
      "location_summary": "Chicago, Illinois • Boston, Massachusetts • Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05009394"
    }
  ]
}