{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Amputation%3B+Traumatic%2C+Limb%2C+Lower&page=2",
    "query": {
      "condition": "Amputation; Traumatic, Limb, Lower",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Amputation%3B+Traumatic%2C+Limb%2C+Lower&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T18:12:14.911Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04038580",
      "title": "A Comparative Assessment of Transfemoral Prosthetic Sockets",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation",
        "Amputation; Traumatic, Leg, Lower"
      ],
      "interventions": [
        {
          "name": "Laminated Socket",
          "type": "DEVICE"
        },
        {
          "name": "Quatro",
          "type": "DEVICE"
        },
        {
          "name": "Infinite Socket",
          "type": "DEVICE"
        },
        {
          "name": "CJ Socket",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2019-08-15",
      "completion_date": "2024-07-01",
      "has_results": true,
      "last_update_posted_date": "2025-09-29",
      "last_synced_at": "2026-06-10T18:12:14.911Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois • Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04038580"
    },
    {
      "nct_id": "NCT04070105",
      "title": "No Power Bionic Lower Extremity Prosthesis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation",
        "Amputation, Traumatic",
        "Amputation; Traumatic, Leg, Lower"
      ],
      "interventions": [
        {
          "name": "Compliant Adaptive Energy Storage and Return Foot",
          "type": "DEVICE"
        },
        {
          "name": "AllPro",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2020-09-01",
      "completion_date": "2022-12-31",
      "has_results": true,
      "last_update_posted_date": "2024-03-27",
      "last_synced_at": "2026-06-10T18:12:14.911Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04070105"
    },
    {
      "nct_id": "NCT02318979",
      "title": "What is the Optimal Stiffness and Height of a Running-specific Prosthesis?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation, Traumatic",
        "Traumatic Amputation of Lower Extremity",
        "Wounds and Injuries"
      ],
      "interventions": [
        {
          "name": "Otto Bock prosthesis",
          "type": "DEVICE"
        },
        {
          "name": "Ossur prosthesis",
          "type": "DEVICE"
        },
        {
          "name": "Freedom Innovations prosthesis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA Eastern Colorado Health Care System",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 30,
      "start_date": "2013-10",
      "completion_date": "2018-01",
      "has_results": true,
      "last_update_posted_date": "2019-07-30",
      "last_synced_at": "2026-06-10T18:12:14.911Z",
      "location_count": 1,
      "location_summary": "Boulder, Colorado",
      "locations": [
        {
          "city": "Boulder",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02318979"
    },
    {
      "nct_id": "NCT06071715",
      "title": "Cryoanalgesia to Treat Phantom Limb Pain Following Above-Knee Amputation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation, Surgical",
        "Amputation, Traumatic",
        "Phantom Limb Pain",
        "Phantom Pain Following Amputation of Lower Limb"
      ],
      "interventions": [
        {
          "name": "ACTIVE cryoneurolysis",
          "type": "DEVICE"
        },
        {
          "name": "SHAM cryoneurolysis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2024-02-12",
      "completion_date": "2025-10-09",
      "has_results": true,
      "last_update_posted_date": "2026-04-08",
      "last_synced_at": "2026-06-10T18:12:14.911Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06071715"
    },
    {
      "nct_id": "NCT01340807",
      "title": "A Comparison of External Mechanical Work Between Different Prosthetic Feet",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Amputation of Lower Extremity"
      ],
      "interventions": [
        {
          "name": "Specialized Functional Prosthetic Training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Miami VA Healthcare System",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "40 Years to 65 Years"
      },
      "enrollment_count": 15,
      "start_date": "2008-03",
      "completion_date": "2011-01",
      "has_results": false,
      "last_update_posted_date": "2011-04-25",
      "last_synced_at": "2026-06-10T18:12:14.911Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01340807"
    },
    {
      "nct_id": "NCT06371209",
      "title": "Kinematics of Ewing Amputees",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lower Extremity Amputation",
        "Trans-Tibial Amputation",
        "Traumatic Lower Extremity Amputation",
        "Agonist-Antagonist Myoneural Interface"
      ],
      "interventions": [
        {
          "name": "Modified Amputation",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard Amputation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 32,
      "start_date": "2022-05-17",
      "completion_date": "2026-07-01",
      "has_results": false,
      "last_update_posted_date": "2025-02-05",
      "last_synced_at": "2026-06-10T18:12:14.911Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06371209"
    },
    {
      "nct_id": "NCT00985842",
      "title": "Study to Determine if Different Prosthetic Sockets Effect How Much Oxygen is in the Tissue of Lower Limb Amputees While They Are Walking",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation",
        "Diabetes Complications",
        "Leg Injuries",
        "Traumatic Amputation"
      ],
      "interventions": [
        {
          "name": "Pe-Lite and sleeve suspension socket",
          "type": "DEVICE"
        },
        {
          "name": "Total Surface bearing a socket with a sleeve suspension but without suction",
          "type": "DEVICE"
        },
        {
          "name": "Total surface bearing suction socket with a pin lock suspension",
          "type": "DEVICE"
        },
        {
          "name": "Total surface bearing suction socket with a sleeve suspension",
          "type": "DEVICE"
        },
        {
          "name": "Vacuum-assisted socket system (Harmony System, Otto Bock)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 7,
      "start_date": "2009-11-01",
      "completion_date": "2012-10-26",
      "has_results": false,
      "last_update_posted_date": "2018-06-29",
      "last_synced_at": "2026-06-10T18:12:14.911Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00985842"
    },
    {
      "nct_id": "NCT00117793",
      "title": "Vacuum Suspension: Effects on Tissue Oxygenation, Activity and Fit",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation",
        "Diabetes",
        "Leg Injuries",
        "Traumatic Amputations"
      ],
      "interventions": [
        {
          "name": "Total Surface Bearing Suction Socket",
          "type": "DEVICE"
        },
        {
          "name": "Vacuum assisted socket system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 20,
      "start_date": "2005-08",
      "completion_date": "2008-09",
      "has_results": true,
      "last_update_posted_date": "2014-08-15",
      "last_synced_at": "2026-06-10T18:12:14.911Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00117793"
    },
    {
      "nct_id": "NCT03027947",
      "title": "Spinal Root and Spinal Cord Stimulation for Restoration of Function in Lower-Limb Amputees",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Amputation of Lower Extremity",
        "Phantom Limb Pain"
      ],
      "interventions": [
        {
          "name": "Spinal cord stimulator",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 5,
      "start_date": "2017-03-16",
      "completion_date": "2021-09-08",
      "has_results": false,
      "last_update_posted_date": "2022-04-12",
      "last_synced_at": "2026-06-10T18:12:14.911Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03027947"
    },
    {
      "nct_id": "NCT04484805",
      "title": "Socket Cooling Effectiveness Take Home Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation",
        "Amputation; Traumatic, Leg, Lower",
        "Amputation Stump",
        "Limb; Absence, Congenital, Lower",
        "Prosthesis User",
        "Lower Limb Amputation Below Knee (Injury)"
      ],
      "interventions": [
        {
          "name": "ICE Condition",
          "type": "DEVICE"
        },
        {
          "name": "Sham Condition",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Liberating Technologies, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 12,
      "start_date": "2019-08-01",
      "completion_date": "2020-11-03",
      "has_results": true,
      "last_update_posted_date": "2024-10-22",
      "last_synced_at": "2026-06-10T18:12:14.911Z",
      "location_count": 2,
      "location_summary": "Holliston, Massachusetts • Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Holliston",
          "state": "Massachusetts"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04484805"
    }
  ]
}