{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anal+Canal&page=2",
    "query": {
      "condition": "Anal Canal",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 62,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anal+Canal&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anal+Canal&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-15T04:35:18.685Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03403465",
      "title": "Intratreatment FDG-PET During Radiation Therapy for Gynecologic and Gastrointestinal Cancers",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cancer of the Cervix",
        "Vulvar Cancer",
        "Esophageal Cancer",
        "Anal Canal Cancer"
      ],
      "interventions": [
        {
          "name": "FDG PET scan",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2018-03-27",
      "completion_date": "2028-04-05",
      "has_results": false,
      "last_update_posted_date": "2026-10-22",
      "last_synced_at": "2026-11-15T04:35:18.685Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03403465"
    },
    {
      "nct_id": "NCT00003867",
      "title": "Irinotecan and Capecitabine in Treating Patients With Solid Tumors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Cancer"
      ],
      "interventions": [
        {
          "name": "capecitabine",
          "type": "DRUG"
        },
        {
          "name": "irinotecan hydrochloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "120 Years",
        "sex": "ALL",
        "summary": "18 Years to 120 Years"
      },
      "enrollment_count": 30,
      "start_date": "1999-03",
      "completion_date": "2003-03",
      "has_results": false,
      "last_update_posted_date": "2018-09-10",
      "last_synced_at": "2026-11-15T04:35:18.685Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00003867"
    },
    {
      "nct_id": "NCT02189161",
      "title": "A Safety and Tolerability of Circumferential Anal Canal Radiofrequency Ablation For Anal Intraepithelial Neoplasia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anal Intraepithelial Neoplasia (AIN)",
        "High-grade Squamous Intraepithelial Lesions (HSIL)"
      ],
      "interventions": [
        {
          "name": "Radiofrequency Ablation (Barrx™)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic - MITG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 10,
      "start_date": "2014-07",
      "completion_date": "2015-08",
      "has_results": true,
      "last_update_posted_date": "2016-07-14",
      "last_synced_at": "2026-11-15T04:35:18.685Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02189161"
    },
    {
      "nct_id": "NCT04276935",
      "title": "Development of a Health-Related Symptom Index for Participants With and Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "High Grade Anal Canal Squamous Intraepithelial Neoplasia",
        "Human Immunodeficiency Virus"
      ],
      "interventions": [
        {
          "name": "Interview",
          "type": "OTHER"
        },
        {
          "name": "Quality-of-Life Assessment",
          "type": "OTHER"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "AIDS Malignancy Consortium",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2018-11-06",
      "completion_date": "2020-03-01",
      "has_results": true,
      "last_update_posted_date": "2025-03-07",
      "last_synced_at": "2026-11-15T04:35:18.685Z",
      "location_count": 4,
      "location_summary": "San Francisco, California • Miami, Florida • Chicago, Illinois + 1 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04276935"
    },
    {
      "nct_id": "NCT01104181",
      "title": "Hybrid Capture 2 Human Papiloma Virus (HPV) High-Risk Anal DNA Test",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anal Canal HPV Infection Diagnosis",
        "Anal Dysplasia Diagnosis",
        "Anal Cancer"
      ],
      "interventions": [
        {
          "name": "HC2 collection kit with a swab or brush",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Laser Surgery Care",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 300,
      "start_date": "2010-03",
      "completion_date": "2011-03",
      "has_results": false,
      "last_update_posted_date": "2011-06-22",
      "last_synced_at": "2026-11-15T04:35:18.685Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01104181"
    },
    {
      "nct_id": "NCT04505553",
      "title": "Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Appendix Carcinoma",
        "Colon Carcinoma",
        "Esophageal Carcinoma",
        "Gastric Carcinoma",
        "Liver and Intrahepatic Bile Duct Carcinoma",
        "Malignant Digestive System Neoplasm",
        "Pancreatic Carcinoma",
        "Rectal Carcinoma",
        "Small Intestinal Carcinoma",
        "Anal Carcinoma",
        "Digestive System Carcinoma",
        "Digestive System Neuroendocrine Tumor",
        "Pancreatic Neuroendocrine Tumor"
      ],
      "interventions": [
        {
          "name": "Acupuncture Therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Acupressure Therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Oral Cryotherapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        },
        {
          "name": "Quality-of-Life Assessment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 78,
      "start_date": "2021-06-01",
      "completion_date": "2024-03-31",
      "has_results": true,
      "last_update_posted_date": "2026-01-21",
      "last_synced_at": "2026-11-15T04:35:18.685Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04505553"
    },
    {
      "nct_id": "NCT02560298",
      "title": "Cisplatin and Fluorouracil Compared With Carboplatin and Paclitaxel in Treating Patients With Inoperable Locally Recurrent or Metastatic Anal Cancer",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anal Basaloid Carcinoma",
        "Anal Canal Cloacogenic Carcinoma",
        "Anal Squamous Cell Carcinoma",
        "Metastatic Anal Canal Carcinoma",
        "Recurrent Anal Canal Carcinoma",
        "Stage IIIB Anal Canal Cancer",
        "Stage IV Anal Canal Cancer"
      ],
      "interventions": [
        {
          "name": "Capecitabine",
          "type": "DRUG"
        },
        {
          "name": "Carboplatin",
          "type": "DRUG"
        },
        {
          "name": "Cisplatin",
          "type": "DRUG"
        },
        {
          "name": "Fluorouracil",
          "type": "DRUG"
        },
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "Paclitaxel",
          "type": "DRUG"
        },
        {
          "name": "Quality-of-Life Assessment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "ECOG-ACRIN Cancer Research Group",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 91,
      "start_date": "2016-08-23",
      "completion_date": "2023-08",
      "has_results": false,
      "last_update_posted_date": "2023-06-22",
      "last_synced_at": "2026-11-15T04:35:18.685Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02560298"
    },
    {
      "nct_id": "NCT04907643",
      "title": "Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer Pain",
        "Visceral Pain",
        "Gastrointestinal Neoplasms",
        "Cancer of Gastrointestinal Tract",
        "Small Intestine Cancer",
        "Pancreas Cancer",
        "Liver Cancer",
        "Colon Cancer",
        "Biliary Tract Cancer",
        "Stomach Cancer",
        "Rectum Cancer",
        "Peritoneal Cancer",
        "Gastrointestinal Cancer Metastatic",
        "Gastrointestinal Cancers - Anus",
        "Gastrointestinal Cancers - Stomach",
        "Gastrointestinal Cancers - Colorectal",
        "Gastrointestinal Cancers - Small Intestine",
        "Small Intestine Cancer Stage III",
        "Small Intestine Cancer Stage IV",
        "Small Intestine Cancer, Recurrent",
        "Pancreas Cancer, Stage III",
        "Pancreas Cancer, Stage IV",
        "Pancreas Cancer, Metastatic",
        "Pancreas Cancer, Recurrent",
        "Liver Cancer Stage IIIa",
        "Liver Cancer Stage IIIb",
        "Liver Cancer Stage IIIc",
        "Liver Cancer Stage IV",
        "Colon Cancer Stage III",
        "Colon Cancer Stage IV",
        "Stomach Cancer Stage III",
        "Stomach Cancer Stage IV",
        "Stomach Cancer Recurrent",
        "Rectum Cancer, Recurrent",
        "Gastrointestinal Cancers - Liver",
        "Anal Cancer",
        "Anal Cancer Stage III",
        "Anal Cancer Stage IV",
        "Anal Cancer Recurrent",
        "Anal Cancer Metastatic",
        "Anal Cancer, Stage IIIA",
        "Anal Cancer, Stage IIIB",
        "Appendix Cancer",
        "Ampullary Cancer",
        "Bile Duct Cancer",
        "Bile Duct Cancer Stage III",
        "Bile Duct Cancer Stage IV",
        "Bile Duct Cancer Stage IVA",
        "Bile Duct Cancer Stage IVB",
        "Bile Duct Cancer Recurrent",
        "Carcinoid Tumor",
        "Carcinoid Tumor of Pancreas",
        "Carcinoid Tumor of Large Intestine",
        "Carcinoid Tumor of GI System",
        "Carcinoid Tumor of Colon",
        "Carcinoid Tumor of Liver",
        "Carcinoid Tumor of Cecum",
        "Carcinoid Tumor of Ileum",
        "Carcinoid Tumor of Rectum",
        "Carcinoid Tumor of the Small Bowel",
        "Carcinoid Tumor of the Stomach",
        "Large Intestine Cancer",
        "Esophagus Cancer",
        "Esophagus Cancer, Stage III",
        "Esophagus Cancer, Stage IV",
        "Esophagus Cancer, Recurrent",
        "Gallbladder Cancer",
        "Gallbladder Cancer Stage III",
        "Gallbladder Cancer Stage IV",
        "Gastric (Stomach) Cancer",
        "Neuroendocrine Tumor",
        "Peritoneum Cancer",
        "Rectal Cancer",
        "Esophagus Cancer, Stage I",
        "Esophagus Cancer, Stage II",
        "Gallbladder Cancer Stage I",
        "Gallbladder Cancer Stage II",
        "Bile Duct Cancer Stage I",
        "Bile Duct Cancer Stage II"
      ],
      "interventions": [
        {
          "name": "PICO G2 4k",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 360,
      "start_date": "2021-10-05",
      "completion_date": "2027-04-16",
      "has_results": false,
      "last_update_posted_date": "2026-11-12",
      "last_synced_at": "2026-11-15T04:35:18.685Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04907643"
    },
    {
      "nct_id": "NCT02437851",
      "title": "Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anal Squamous Cell Carcinoma",
        "HIV Infection",
        "Stage 0 Anal Canal Cancer",
        "Stage I Anal Canal Cancer"
      ],
      "interventions": [
        {
          "name": "Therapeutic Conventional Surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "AIDS Malignancy Consortium",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 16,
      "start_date": "2015-04",
      "completion_date": "2026-04-15",
      "has_results": false,
      "last_update_posted_date": "2026-04-20",
      "last_synced_at": "2026-11-15T04:35:18.685Z",
      "location_count": 5,
      "location_summary": "San Francisco, California • Atlanta, Georgia • Boston, Massachusetts + 2 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02437851"
    },
    {
      "nct_id": "NCT03896958",
      "title": "The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cancer, All Types",
        "Cancer of Liver",
        "Cancer of Stomach",
        "Cancer of Head and Neck",
        "Cancer of Rectum",
        "Cancer of Kidney",
        "Cancer of Esophagus",
        "Cancer of Colon",
        "Cancer Skin",
        "Cancer of Cervix",
        "Cancer, Metastatic",
        "Cancer of Larynx",
        "Cancer of Neck",
        "Cancer of Lung",
        "Cancer of Brain and Nervous System",
        "Cancer of Vulva, Disseminated",
        "Cancer of Pancreas",
        "Sarcoma",
        "GIST",
        "Small-cell Lung Cancer",
        "Adenocarcinoma Lung",
        "Cancer of Prostate",
        "Cancer, Advanced",
        "Adrenal Cancer",
        "Testicular Cancer",
        "Uterine Cancer",
        "Bronchoalveolar Cell Lung Cancer",
        "Cancer Unknown Primary",
        "Glioblastoma Multiforme",
        "Oligodendroglioma",
        "Breast Cancer",
        "Renal Cell Carcinoma",
        "Hepatocellular Carcinoma",
        "Cholangiocarcinoma",
        "Squamous Cell Carcinoma",
        "Transitional Cell Carcinoma",
        "Cancer, Other",
        "Cancer, Anal",
        "Melanoma",
        "Cancer, Bile Duct",
        "Cancer, Bladder",
        "Cancer Cords Vocal",
        "Cancers Cell Neuroendocrine",
        "Cancer Differentiated Poorly",
        "Cancer, Anaplastic Thyroid"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "SpeciCare",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "1 Month to 99 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2019-03-21",
      "completion_date": "2024-03-12",
      "has_results": false,
      "last_update_posted_date": "2020-12-04",
      "last_synced_at": "2026-11-15T04:35:18.685Z",
      "location_count": 1,
      "location_summary": "Gainesville, Georgia",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03896958"
    }
  ]
}