{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Analgesic+Response",
    "query": {
      "condition": "Analgesic Response"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 19,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Analgesic+Response&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T06:47:53.745Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02136784",
      "title": "Analgesic Response to Opioid Analgesics in Buprenorphine-Maintained Individuals",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Analgesic Response"
      ],
      "interventions": [
        {
          "name": "morphine sulfate",
          "type": "DRUG"
        },
        {
          "name": "hydrocodone",
          "type": "DRUG"
        },
        {
          "name": "hydromorphone HCI",
          "type": "DRUG"
        },
        {
          "name": "oxycodone",
          "type": "DRUG"
        },
        {
          "name": "buprenorphine",
          "type": "DRUG"
        },
        {
          "name": "oral tablet placebo",
          "type": "DRUG"
        },
        {
          "name": "sublingual tablet placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "50 Years",
        "sex": "MALE",
        "summary": "20 Years to 50 Years · Male only"
      },
      "enrollment_count": 12,
      "start_date": "2014-04",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2014-05-13",
      "last_synced_at": "2026-07-23T06:47:53.745Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02136784"
    },
    {
      "nct_id": "NCT03893175",
      "title": "Towards Predicting the Analgesic Response to Ibuprofen Following Third-molar Extraction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Impacted Third Molar Tooth",
        "Pain, Acute"
      ],
      "interventions": [
        {
          "name": "Ibuprofen",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Oxycodone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 86,
      "start_date": "2019-05-10",
      "completion_date": "2022-03-02",
      "has_results": false,
      "last_update_posted_date": "2025-07-24",
      "last_synced_at": "2026-07-23T06:47:53.745Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03893175"
    },
    {
      "nct_id": "NCT04470050",
      "title": "Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Opioid Withdrawal"
      ],
      "interventions": [
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "BioXcel Therapeutics Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 225,
      "start_date": "2020-06-09",
      "completion_date": "2021-02-18",
      "has_results": true,
      "last_update_posted_date": "2026-06-03",
      "last_synced_at": "2026-07-23T06:47:53.745Z",
      "location_count": 3,
      "location_summary": "Miami Lakes, Florida • Marlton, New Jersey • New York, New York",
      "locations": [
        {
          "city": "Miami Lakes",
          "state": "Florida"
        },
        {
          "city": "Marlton",
          "state": "New Jersey"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04470050"
    },
    {
      "nct_id": "NCT04395001",
      "title": "Pain Response Evaluation of a Combined Intervention to Cope Effectively",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "duloxetine",
          "type": "DRUG"
        },
        {
          "name": "Web-based Cognitive Behavioral Therapy (CBT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nurse-delivered Motivational Interviewing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 280,
      "start_date": "2021-02-24",
      "completion_date": "2024-07-18",
      "has_results": true,
      "last_update_posted_date": "2025-10-10",
      "last_synced_at": "2026-07-23T06:47:53.745Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04395001"
    },
    {
      "nct_id": "NCT01057381",
      "title": "Dexmedetomidine in Pediatric Tonsillectomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pediatric Adenotonsillectomy",
        "Post Operative Analgesia"
      ],
      "interventions": [
        {
          "name": "Dexmedetomidine 0.75 mcg/kg",
          "type": "DRUG"
        },
        {
          "name": "Morphine 50 mcg/kg",
          "type": "DRUG"
        },
        {
          "name": "Morphine 100 mcg/kg",
          "type": "DRUG"
        },
        {
          "name": "Dexmedetomidine 1 mcg/kg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "3 Years to 17 Years"
      },
      "enrollment_count": 109,
      "start_date": "2005-08",
      "completion_date": "2010-12",
      "has_results": true,
      "last_update_posted_date": "2021-07-27",
      "last_synced_at": "2026-07-23T06:47:53.745Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01057381"
    },
    {
      "nct_id": "NCT00986882",
      "title": "To Evaluate the Safety, Tolerability and Analgesic Efficacy of SAF312 in Postoperative Dental Pain Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "SAF312A",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Ibuprofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 183,
      "start_date": "2009-09",
      "completion_date": "2011-03",
      "has_results": false,
      "last_update_posted_date": "2020-12-19",
      "last_synced_at": "2026-07-23T06:47:53.745Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00986882"
    },
    {
      "nct_id": "NCT00701909",
      "title": "Pain Medicine for Wound Care Procedures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Wound Care",
        "Pain Intensity",
        "Hyperalgesia",
        "Nausea",
        "Vomiting",
        "Hallucinations"
      ],
      "interventions": [
        {
          "name": "Morphine plus Ketamine",
          "type": "DRUG"
        },
        {
          "name": "Morphine plus Saline (placebo)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 12,
      "start_date": "2008-06",
      "completion_date": "2009-04",
      "has_results": true,
      "last_update_posted_date": "2024-03-26",
      "last_synced_at": "2026-07-23T06:47:53.745Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00701909"
    },
    {
      "nct_id": "NCT04862871",
      "title": "Enhancing Analgesia in Chronic Pain Through Exercise",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain",
        "Chronic Widespread Pain",
        "Fibromyalgia"
      ],
      "interventions": [
        {
          "name": "Physical Activity - Pediatric Pain Rehabilitation Center",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "24 Years",
        "sex": "ALL",
        "summary": "10 Years to 24 Years"
      },
      "enrollment_count": 30,
      "start_date": "2022-04-01",
      "completion_date": "2022-11",
      "has_results": false,
      "last_update_posted_date": "2022-05-11",
      "last_synced_at": "2026-07-23T06:47:53.745Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04862871"
    },
    {
      "nct_id": "NCT06539741",
      "title": "Variability in Analgesic Response to Ibuprofen",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Impacted Third Molar Tooth",
        "Pain, Acute"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2025-01-03",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2026-05-06",
      "last_synced_at": "2026-07-23T06:47:53.745Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06539741"
    },
    {
      "nct_id": "NCT07336264",
      "title": "Characterization of Acute Pain",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Pain, Postoperative",
        "Postoperative Pain",
        "Acute Pain"
      ],
      "interventions": [
        {
          "name": "AlgometRx Nociometer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's National Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "6 Years to 21 Years"
      },
      "enrollment_count": 100,
      "start_date": "2025-12-02",
      "completion_date": "2028-06-02",
      "has_results": false,
      "last_update_posted_date": "2026-01-14",
      "last_synced_at": "2026-07-23T06:47:53.745Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07336264"
    }
  ]
}