{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anencephaly-Spina+Bifida",
    "query": {
      "condition": "Anencephaly-Spina Bifida"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 5,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T06:46:32.105Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06904612",
      "title": "Using Iodized Salt to Improve Serum Folate, B12 and Iron Levels",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neural Tube Defects",
        "Folic Acid Deficiency",
        "Spina Bifida",
        "Anencephaly-Spina Bifida",
        "B12 Deficiency Vitamin",
        "Anemia",
        "Iron Deficiency Anaemia Due to Dietary Causes"
      ],
      "interventions": [
        {
          "name": "Micronutrient fortified iodized salt",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Hydrocephalus and Neuroscience Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 200,
      "start_date": "2022-06-01",
      "completion_date": "2022-11-30",
      "has_results": false,
      "last_update_posted_date": "2025-07-14",
      "last_synced_at": "2026-05-22T06:46:32.105Z",
      "location_count": 1,
      "location_summary": "Orlando, Florida",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06904612"
    },
    {
      "nct_id": "NCT01253746",
      "title": "Genetics of Neural Tube Defects",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neural Tube Defects"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "John P. Hussman Institute for Human Genomics",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 6000,
      "start_date": "2009-04",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2010-12-03",
      "last_synced_at": "2026-05-22T06:46:32.105Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01253746"
    },
    {
      "nct_id": "NCT00636233",
      "title": "Genetics of Spina Bifida and Anencephaly",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anencephaly",
        "Acrania"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 10000,
      "start_date": "1993-05",
      "completion_date": "2017-08-02",
      "has_results": false,
      "last_update_posted_date": "2020-04-02",
      "last_synced_at": "2026-05-22T06:46:32.105Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00636233"
    },
    {
      "nct_id": "NCT00031122",
      "title": "Study of Genetic Risk Factors for Spina Bifida and Anencephaly",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spina Bifida",
        "Anencephaly"
      ],
      "interventions": [
        {
          "name": "No Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1100,
      "start_date": "2000-09",
      "completion_date": "2012-09",
      "has_results": false,
      "last_update_posted_date": "2010-10-05",
      "last_synced_at": "2026-05-22T06:46:32.105Z",
      "location_count": 2,
      "location_summary": "Philadelphia, Pennsylvania • Houston, Texas",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00031122"
    },
    {
      "nct_id": "NCT06174883",
      "title": "Salt-FA to Increase Folate Levels",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neural Tube Defects",
        "Folic Acid Deficiency",
        "Spina Bifida",
        "Anencephaly-Spina Bifida"
      ],
      "interventions": [
        {
          "name": "Folic acid fortified iodized salt",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Hydrocephalus and Neuroscience Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 80,
      "start_date": "2022-06-01",
      "completion_date": "2022-11-30",
      "has_results": false,
      "last_update_posted_date": "2023-12-19",
      "last_synced_at": "2026-05-22T06:46:32.105Z",
      "location_count": 1,
      "location_summary": "Orlando, Florida",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06174883"
    }
  ]
}