{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anesthesia%3B+Adverse+Effect",
    "query": {
      "condition": "Anesthesia; Adverse Effect"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 25,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anesthesia%3B+Adverse+Effect&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:44:20.699Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06093893",
      "title": "Hypotensive Anesthesia for Orthognathic Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hypotensive Anesthesia",
        "Orthognathic Surgery"
      ],
      "interventions": [
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        },
        {
          "name": "Nicardipine",
          "type": "DRUG"
        },
        {
          "name": "Labetalol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2025-03-04",
      "completion_date": "2026-02-06",
      "has_results": false,
      "last_update_posted_date": "2026-03-31",
      "last_synced_at": "2026-05-22T05:44:20.699Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06093893"
    },
    {
      "nct_id": "NCT04679818",
      "title": "Postoperative Consequences of Intraoperative NOL Titration",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Anesthesia; Adverse Effect"
      ],
      "interventions": [
        {
          "name": "Routine opioid management",
          "type": "DRUG"
        },
        {
          "name": "PMD-200 Nol-guided opioid administration",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "21 Years to 85 Years"
      },
      "enrollment_count": 72,
      "start_date": "2020-12-30",
      "completion_date": "2023-01-10",
      "has_results": true,
      "last_update_posted_date": "2024-06-21",
      "last_synced_at": "2026-05-22T05:44:20.699Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04679818"
    },
    {
      "nct_id": "NCT05358535",
      "title": "Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Anesthesia",
        "Propofol Adverse Reaction",
        "Etomidate Adverse Reaction",
        "Anesthesia Complication",
        "Anesthesia; Adverse Effect",
        "Anesthesia; Reaction"
      ],
      "interventions": [
        {
          "name": "Admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2)",
          "type": "DRUG"
        },
        {
          "name": "Admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2022-09-19",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2026-01-20",
      "last_synced_at": "2026-05-22T05:44:20.699Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05358535"
    },
    {
      "nct_id": "NCT05109000",
      "title": "Comparison of Subcutaneous Injection of Normal Saline and Bacteriostatic Saline",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Injection Site Irritation",
        "Injection Site Bruising",
        "Injection Site Discomfort",
        "Benzoic Acid Adverse Reaction",
        "Anesthesia, Local"
      ],
      "interventions": [
        {
          "name": "Sodium Chloride 0.9% Inj",
          "type": "DRUG"
        },
        {
          "name": "Bacteriostatic Sodium Chloride 0.9 % INJECTION VIAL (ML)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jeffrey Alan Klein, MD",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 32,
      "start_date": "2021-11",
      "completion_date": "2022-01",
      "has_results": false,
      "last_update_posted_date": "2021-11-05",
      "last_synced_at": "2026-05-22T05:44:20.699Z",
      "location_count": 1,
      "location_summary": "San Juan Capistrano, California",
      "locations": [
        {
          "city": "San Juan Capistrano",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05109000"
    },
    {
      "nct_id": "NCT03699696",
      "title": "A Pilot Analysis of the Association Between Anesthesia Induction Dosing and AKI in the Elderly Population",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Kidney Injury",
        "Hypotension",
        "Anesthesia; Adverse Effect"
      ],
      "interventions": [
        {
          "name": "Propofol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 541,
      "start_date": "2014-12-01",
      "completion_date": "2018-07-08",
      "has_results": false,
      "last_update_posted_date": "2019-01-24",
      "last_synced_at": "2026-05-22T05:44:20.699Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03699696"
    },
    {
      "nct_id": "NCT04688346",
      "title": "Cardiovascular Effects of Racemic Epinephrine Pellets",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Epinephrine Causing Adverse Effects in Therapeutic Use"
      ],
      "interventions": [
        {
          "name": "HemeRX epinephrine pellets",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "9 Years",
        "sex": "ALL",
        "summary": "2 Years to 9 Years"
      },
      "enrollment_count": 13,
      "start_date": "2019-06-10",
      "completion_date": "2019-11-30",
      "has_results": true,
      "last_update_posted_date": "2021-05-13",
      "last_synced_at": "2026-05-22T05:44:20.699Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04688346"
    },
    {
      "nct_id": "NCT03882788",
      "title": "The Effect of Anesthesia on Neurodevelopmental Outcome (NDO)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anesthesia; Adverse Effect",
        "Congenital Heart Disease",
        "Neurodevelopmental Disorders"
      ],
      "interventions": [
        {
          "name": "Isoflurane",
          "type": "DRUG"
        },
        {
          "name": "Fentanyl (high dose)",
          "type": "DRUG"
        },
        {
          "name": "Fentanyl (low dose)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "36 Months",
        "sex": "ALL",
        "summary": "1 Day to 36 Months"
      },
      "enrollment_count": 153,
      "start_date": "2013-04-22",
      "completion_date": "2020-11-19",
      "has_results": true,
      "last_update_posted_date": "2022-05-09",
      "last_synced_at": "2026-05-22T05:44:20.699Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03882788"
    },
    {
      "nct_id": "NCT04322994",
      "title": "THRIVE Use in Pediatric Populations- Multi Site",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Oxygen Deficiency",
        "Desaturation of Blood",
        "Hypoventilation",
        "Anesthesia; Adverse Effect"
      ],
      "interventions": [
        {
          "name": "Transnasal Humidified Rapid-Insufflation Ventilatory Echange",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 175,
      "start_date": "2020-10-21",
      "completion_date": "2024-01-19",
      "has_results": true,
      "last_update_posted_date": "2025-03-27",
      "last_synced_at": "2026-05-22T05:44:20.699Z",
      "location_count": 5,
      "location_summary": "Palo Alto, California • Chicago, Illinois • Boston, Massachusetts + 2 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04322994"
    },
    {
      "nct_id": "NCT02850887",
      "title": "Patient Positioning and Airway Management During ERCP",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Airway Management"
      ],
      "interventions": [
        {
          "name": "general endotracheal anesthesia",
          "type": "OTHER"
        },
        {
          "name": "deep sedation without endotracheal intubation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2016-07-25",
      "completion_date": "2018-01-04",
      "has_results": false,
      "last_update_posted_date": "2018-02-06",
      "last_synced_at": "2026-05-22T05:44:20.699Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02850887"
    },
    {
      "nct_id": "NCT02101047",
      "title": "Phenylephrine Dose and Mode of Administration for Spinal Anesthesia Induced Hypotension",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Complications; Cesarean Section",
        "Spinal Anesthetics Causing Adverse Effects in Therapeutic Use"
      ],
      "interventions": [
        {
          "name": "Phenylephrine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2015-08",
      "completion_date": "2016-12-31",
      "has_results": false,
      "last_update_posted_date": "2017-11-08",
      "last_synced_at": "2026-05-22T05:44:20.699Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02101047"
    }
  ]
}