{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anesthesia%3B+Reaction",
    "query": {
      "condition": "Anesthesia; Reaction"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anesthesia%3B+Reaction&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T06:43:31.717Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05358535",
      "title": "Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Anesthesia",
        "Propofol Adverse Reaction",
        "Etomidate Adverse Reaction",
        "Anesthesia Complication",
        "Anesthesia; Adverse Effect",
        "Anesthesia; Reaction"
      ],
      "interventions": [
        {
          "name": "Admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2)",
          "type": "DRUG"
        },
        {
          "name": "Admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2022-09-19",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2026-01-20",
      "last_synced_at": "2026-05-22T06:43:31.717Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05358535"
    },
    {
      "nct_id": "NCT05109000",
      "title": "Comparison of Subcutaneous Injection of Normal Saline and Bacteriostatic Saline",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Injection Site Irritation",
        "Injection Site Bruising",
        "Injection Site Discomfort",
        "Benzoic Acid Adverse Reaction",
        "Anesthesia, Local"
      ],
      "interventions": [
        {
          "name": "Sodium Chloride 0.9% Inj",
          "type": "DRUG"
        },
        {
          "name": "Bacteriostatic Sodium Chloride 0.9 % INJECTION VIAL (ML)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jeffrey Alan Klein, MD",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 32,
      "start_date": "2021-11",
      "completion_date": "2022-01",
      "has_results": false,
      "last_update_posted_date": "2021-11-05",
      "last_synced_at": "2026-05-22T06:43:31.717Z",
      "location_count": 1,
      "location_summary": "San Juan Capistrano, California",
      "locations": [
        {
          "city": "San Juan Capistrano",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05109000"
    },
    {
      "nct_id": "NCT04435834",
      "title": "Individual Cerebral Hemodynamic Oxygenation Relationships",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Anesthesia",
        "Anesthesia; Reaction"
      ],
      "interventions": [
        {
          "name": "Propofol or Sevoflurane",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Matthew Borzage",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": 30,
      "start_date": "2020-06-09",
      "completion_date": "2026-09-10",
      "has_results": false,
      "last_update_posted_date": "2024-09-03",
      "last_synced_at": "2026-05-22T06:43:31.717Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04435834"
    },
    {
      "nct_id": "NCT05383417",
      "title": "No Post Intubation Laryngeal Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sore-throat",
        "Dysphonia",
        "Dysphagia",
        "Intubation Complication",
        "Anesthesia Intubation Complication",
        "Anesthesia Morbidity",
        "Anesthesia Complication",
        "Anesthesia; Adverse Effect",
        "Anesthesia; Reaction",
        "Throat Disorder",
        "Throat; Wound",
        "Throat Injury"
      ],
      "interventions": [
        {
          "name": "EndoClip",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2022-11-08",
      "completion_date": "2023-09-21",
      "has_results": true,
      "last_update_posted_date": "2025-09-10",
      "last_synced_at": "2026-05-22T06:43:31.717Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05383417"
    },
    {
      "nct_id": "NCT02361944",
      "title": "Risk of Oxygen During Cardiac Surgery Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Cardiac Surgery"
      ],
      "interventions": [
        {
          "name": "Oxygen - normoxia",
          "type": "DRUG"
        },
        {
          "name": "Oxygen - hyperoxia",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 213,
      "start_date": "2016-04-05",
      "completion_date": "2021-01-08",
      "has_results": true,
      "last_update_posted_date": "2024-02-01",
      "last_synced_at": "2026-05-22T06:43:31.717Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02361944"
    },
    {
      "nct_id": "NCT06326983",
      "title": "Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tonsillitis",
        "Post-operative Nausea and Vomiting (PONV)",
        "Emergence Delirium",
        "Opioid Analgesic Adverse Reaction",
        "Anesthesia",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "Ketorolac",
          "type": "DRUG"
        },
        {
          "name": "Morphine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "3 Years to 17 Years"
      },
      "enrollment_count": 62,
      "start_date": "2024-05-09",
      "completion_date": "2026-03-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-18",
      "last_synced_at": "2026-05-22T06:43:31.717Z",
      "location_count": 1,
      "location_summary": "Waltham, Massachusetts",
      "locations": [
        {
          "city": "Waltham",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06326983"
    },
    {
      "nct_id": "NCT07577726",
      "title": "Prospective Observational Multimodal Neuromonitoring During High-Risk Adult Surgery",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Postoperative Cognitive Complications",
        "Delirium",
        "Perioperative/Postoperative Complications",
        "Brain Injuries",
        "Anesthesia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2026-07",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-05-11",
      "last_synced_at": "2026-05-22T06:43:31.717Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07577726"
    },
    {
      "nct_id": "NCT03839784",
      "title": "Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cognitive Decline",
        "Cognitive Change",
        "Cognitive Impairment",
        "Postoperative Delirium",
        "Anesthesia; Reaction",
        "Anesthesia; Adverse Effect"
      ],
      "interventions": [
        {
          "name": "Neurocognition Interventions",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 250,
      "start_date": "2020-09-01",
      "completion_date": "2030-08-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-23",
      "last_synced_at": "2026-05-22T06:43:31.717Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03839784"
    },
    {
      "nct_id": "NCT05899686",
      "title": "Effect of Location of Tetanic Stimuli on Photoplethysmogram Under General Anesthesia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress Reaction"
      ],
      "interventions": [
        {
          "name": "Tetanic Stimulus",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2016-01-27",
      "completion_date": "2016-05-12",
      "has_results": true,
      "last_update_posted_date": "2024-05-16",
      "last_synced_at": "2026-05-22T06:43:31.717Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05899686"
    },
    {
      "nct_id": "NCT02862912",
      "title": "Chloroprocaine Spinal Anesthesia for Cervical Cerclage (CP Spinal)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Adverse Reaction to Spinal Anesthetic",
        "Maternal Care for Cervical Incompetence"
      ],
      "interventions": [
        {
          "name": "Chloroprocaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Fentanyl",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 43,
      "start_date": "2016-11-08",
      "completion_date": "2020-01-31",
      "has_results": true,
      "last_update_posted_date": "2020-12-24",
      "last_synced_at": "2026-05-22T06:43:31.717Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02862912"
    }
  ]
}