{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ankle",
    "query": {
      "condition": "Ankle"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 425,
    "total_pages": 43,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ankle&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T03:00:25.861Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03481725",
      "title": "Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation: A Department of Defense Funded Multicenter Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rotator Cuff Repair",
        "Anterior Cruciate Ligament Reconstruction",
        "Ankle Arthrodesis or Arthroplasty",
        "Hallux Valgus Correction"
      ],
      "interventions": [
        {
          "name": "ACTIVE peripheral nerve stimulation with a percutaneously inserted lead and wearable stimulator (SPR Therapeutics, Cleveland, Ohio)",
          "type": "DEVICE"
        },
        {
          "name": "SHAM peripheral nerve stimulation with a percutaneously inserted lead and wearable SHAM stimulator (SPR Therapeutics, Cleveland, Ohio)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2018-07-14",
      "completion_date": "2021-01-07",
      "has_results": true,
      "last_update_posted_date": "2021-03-18",
      "last_synced_at": "2026-07-22T03:00:25.861Z",
      "location_count": 6,
      "location_summary": "San Diego, California • Bethesda, Maryland • Fort Bragg, North Carolina + 2 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Fort Bragg",
          "state": "North Carolina"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03481725"
    },
    {
      "nct_id": "NCT06428448",
      "title": "Study to Evaluate the REMEDY SPECTRUM GV IM Spacer Nail in the Treatment of Ankle-Related Infections",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Periprosthetic Joint Infection"
      ],
      "interventions": [
        {
          "name": "REMEDY Spectrum IM Spacer Nail",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "OsteoRemedies, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2026-02-01",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-07-22T03:00:25.861Z",
      "location_count": 3,
      "location_summary": "Lansing, Michigan • Charlotte, North Carolina • Durham, North Carolina",
      "locations": [
        {
          "city": "Lansing",
          "state": "Michigan"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06428448"
    },
    {
      "nct_id": "NCT02334618",
      "title": "Insole Sensor to Determine Optimal Limb Loading in the Rehabilitation of Ankle Fractures",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ankle Fracture"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 38,
      "start_date": "2014-08",
      "completion_date": "2017-07-13",
      "has_results": false,
      "last_update_posted_date": "2017-10-26",
      "last_synced_at": "2026-07-22T03:00:25.861Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02334618"
    },
    {
      "nct_id": "NCT00601471",
      "title": "Effects of Proximal and Distal Tibiofibular Joint Manipulation on Lower Extremity Muscle Activation, Ankle Range of Motion, and Functional Outcome Scores in Individuals With Chronic Ankle Instability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Sprain",
        "Ankle Injuries",
        "Sprain"
      ],
      "interventions": [
        {
          "name": "proximal tibiofibular manipulation",
          "type": "OTHER"
        },
        {
          "name": "distal tibiofibular manipulation",
          "type": "OTHER"
        },
        {
          "name": "no intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 61,
      "start_date": "2007-04",
      "completion_date": "2010-01",
      "has_results": false,
      "last_update_posted_date": "2010-06-24",
      "last_synced_at": "2026-07-22T03:00:25.861Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00601471"
    },
    {
      "nct_id": "NCT06719609",
      "title": "Enovis High Ankle Sprain Brace Testing",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Athletes in Cutting Sports"
      ],
      "interventions": [
        {
          "name": "Ankle tape",
          "type": "OTHER"
        },
        {
          "name": "Standard lace-up ankle brace",
          "type": "OTHER"
        },
        {
          "name": "Standard high ankle-sprain (HAS) brace",
          "type": "OTHER"
        },
        {
          "name": "Low-profile HAS brace",
          "type": "OTHER"
        },
        {
          "name": "No ankle brace or tape",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 30,
      "start_date": "2026-08",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2026-05-29",
      "last_synced_at": "2026-07-22T03:00:25.861Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06719609"
    },
    {
      "nct_id": "NCT04930406",
      "title": "Impact of Physical Therapy Intervention on Foot and Ankle Function",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neoplasms",
        "Physical Therapy Modalities",
        "Survivorship"
      ],
      "interventions": [
        {
          "name": "Physical therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Children's Hospitals and Clinics of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "7 Years to 30 Years"
      },
      "enrollment_count": 80,
      "start_date": "2012-12-18",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-02-20",
      "last_synced_at": "2026-07-22T03:00:25.861Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04930406"
    },
    {
      "nct_id": "NCT00494403",
      "title": "Chronic Ankle Instability and Proprioception",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Ankle Sprains"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Logan College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "20 Years to 65 Years"
      },
      "enrollment_count": 60,
      "start_date": "2009-08",
      "completion_date": "2010-08",
      "has_results": false,
      "last_update_posted_date": "2013-05-03",
      "last_synced_at": "2026-07-22T03:00:25.861Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00494403"
    },
    {
      "nct_id": "NCT06692686",
      "title": "AFO Prescription to Optimize Post-Stroke Function",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Foot Orthosis (AFO)",
        "Stroke Patients",
        "Post-Stroke Hemiparesis"
      ],
      "interventions": [
        {
          "name": "Pre-fabricated (PF) ankle-foot orthosis (AFO)",
          "type": "DEVICE"
        },
        {
          "name": "Carbon-strut (CS) ankle-foot orthosis (AFO)",
          "type": "DEVICE"
        },
        {
          "name": "Multifunctional articulating (MA) ankle-foot orthosis (AFO)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2025-07-08",
      "completion_date": "2027-10",
      "has_results": false,
      "last_update_posted_date": "2025-08-21",
      "last_synced_at": "2026-07-22T03:00:25.861Z",
      "location_count": 4,
      "location_summary": "Downey, California • Jacksonville, Florida • Charleston, South Carolina + 1 more",
      "locations": [
        {
          "city": "Downey",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06692686"
    },
    {
      "nct_id": "NCT04575688",
      "title": "Periarticular Injection Versus Popliteal Block",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Foot Surgery",
        "Ankle Surgery"
      ],
      "interventions": [
        {
          "name": "Exparel",
          "type": "DRUG"
        },
        {
          "name": "Bupivicaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Campbell Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 100,
      "start_date": "2021-07-13",
      "completion_date": "2027-02-28",
      "has_results": false,
      "last_update_posted_date": "2025-12-24",
      "last_synced_at": "2026-07-22T03:00:25.861Z",
      "location_count": 1,
      "location_summary": "Germantown, Tennessee",
      "locations": [
        {
          "city": "Germantown",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04575688"
    },
    {
      "nct_id": "NCT00927641",
      "title": "HKT-500 in the Treatment of Adult Patients With Ankle Sprain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Ankle Sprain"
      ],
      "interventions": [
        {
          "name": "Ketoprofen Patch",
          "type": "DRUG"
        },
        {
          "name": "Placebo Patch",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Hisamitsu Pharmaceutical Co., Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 240,
      "start_date": "2009-07",
      "completion_date": "2010-11",
      "has_results": false,
      "last_update_posted_date": "2015-06-04",
      "last_synced_at": "2026-07-22T03:00:25.861Z",
      "location_count": 25,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 21 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Hot Springs",
          "state": "Arkansas"
        },
        {
          "city": "Anaheim",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00927641"
    }
  ]
}