{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ankle+Foot+Orthosis+%28AFO%29",
    "query": {
      "condition": "Ankle Foot Orthosis (AFO)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ankle+Foot+Orthosis+%28AFO%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T06:07:39.502Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06692686",
      "title": "AFO Prescription to Optimize Post-Stroke Function",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Foot Orthosis (AFO)",
        "Stroke Patients",
        "Post-Stroke Hemiparesis"
      ],
      "interventions": [
        {
          "name": "Pre-fabricated (PF) ankle-foot orthosis (AFO)",
          "type": "DEVICE"
        },
        {
          "name": "Carbon-strut (CS) ankle-foot orthosis (AFO)",
          "type": "DEVICE"
        },
        {
          "name": "Multifunctional articulating (MA) ankle-foot orthosis (AFO)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2025-07-08",
      "completion_date": "2027-10",
      "has_results": false,
      "last_update_posted_date": "2025-08-21",
      "last_synced_at": "2026-07-22T06:07:39.502Z",
      "location_count": 4,
      "location_summary": "Downey, California • Jacksonville, Florida • Charleston, South Carolina + 1 more",
      "locations": [
        {
          "city": "Downey",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06692686"
    },
    {
      "nct_id": "NCT02819011",
      "title": "OHI--Randomized Control Trial to Evaluate Efficacy, Acceptability, and Perception of Benefit of an Innovative Custom AFO",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Accidental Falls",
        "Fall Due to Loss of Equilibrium",
        "High Risk of Falls Due to Mobility Limitation",
        "Diabetes",
        "Arthritis",
        "Cancer",
        "Peripheral Arterial Disease",
        "Parkinson's Disease",
        "End Stage Renal Failure on Dialysis"
      ],
      "interventions": [
        {
          "name": "MBB AFO",
          "type": "DEVICE"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Bijan Najafi, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2016-05",
      "completion_date": "2019-04-04",
      "has_results": true,
      "last_update_posted_date": "2020-02-27",
      "last_synced_at": "2026-07-22T06:07:39.502Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02819011"
    },
    {
      "nct_id": "NCT07434492",
      "title": "Smart AFO and 5-Azacitidine to Enhance Mobility in Children With Cerebral Palsy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cerebral Palsy"
      ],
      "interventions": [
        {
          "name": "Smart Ankle-Foot Orthosis",
          "type": "DEVICE"
        },
        {
          "name": "5-Azacitidine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Shirley Ryan AbilityLab",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "8 Years to 17 Years"
      },
      "enrollment_count": 60,
      "start_date": "2026-05-28",
      "completion_date": "2030-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-01",
      "last_synced_at": "2026-07-22T06:07:39.502Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07434492"
    },
    {
      "nct_id": "NCT01798927",
      "title": "Effect of Lower Extremity Ankle Foot Orthoses in Parkinson's Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson's Disease"
      ],
      "interventions": [
        {
          "name": "Ankle foot orthosis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "50 Years to 75 Years"
      },
      "enrollment_count": 4,
      "start_date": "2012-12",
      "completion_date": "2013-07",
      "has_results": true,
      "last_update_posted_date": "2015-08-03",
      "last_synced_at": "2026-07-22T06:07:39.502Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01798927"
    },
    {
      "nct_id": "NCT01138995",
      "title": "Clinical Study of the L300 Versus Ankle-foot Orthosis (AFO) on Post-Stroke Subjects With Foot Drop",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sensorimotor Gait Disorder",
        "Neurologic Ambulation Disorder",
        "Gait, Drop Foot",
        "Poststroke Hemiparesis",
        "Post-Cerebrovascular Accident (CVA) Hemiparesis"
      ],
      "interventions": [
        {
          "name": "Ness L300",
          "type": "DEVICE"
        },
        {
          "name": "Ankle-foot orthosis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Bioness Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 197,
      "start_date": "2010-05",
      "completion_date": "2013-02",
      "has_results": true,
      "last_update_posted_date": "2016-04-28",
      "last_synced_at": "2026-07-22T06:07:39.502Z",
      "location_count": 11,
      "location_summary": "Downey, California • Long Beach, California • San Diego, California + 8 more",
      "locations": [
        {
          "city": "Downey",
          "state": "California"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01138995"
    },
    {
      "nct_id": "NCT01796860",
      "title": "Effectiveness of Ankle Foot Orthoses on Gait in Multiple Sclerosis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "AFO",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 10,
      "start_date": "2012-09",
      "completion_date": "2013-08",
      "has_results": true,
      "last_update_posted_date": "2015-08-21",
      "last_synced_at": "2026-07-22T06:07:39.502Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01796860"
    },
    {
      "nct_id": "NCT06127264",
      "title": "Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy",
        "Ankle Foot Orthosis (AFO)",
        "Peripheral Neuropathy"
      ],
      "interventions": [
        {
          "name": "Carbon Fiber Custom Dynamic Orthosis (CDO)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 60,
      "start_date": "2024-03-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-31",
      "last_synced_at": "2026-07-22T06:07:39.502Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06127264"
    },
    {
      "nct_id": "NCT05619484",
      "title": "Smart Ankle-Foot Orthosis to Improve Stroke Outcomes: Smart AFO",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Stroke"
      ],
      "interventions": [
        {
          "name": "Smart AFO",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Orthocare Innovations, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2022-08-15",
      "completion_date": "2024-08-31",
      "has_results": false,
      "last_update_posted_date": "2023-10-10",
      "last_synced_at": "2026-07-22T06:07:39.502Z",
      "location_count": 3,
      "location_summary": "Troy, Michigan • Salt Lake City, Utah • Edmonds, Washington",
      "locations": [
        {
          "city": "Troy",
          "state": "Michigan"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        },
        {
          "city": "Edmonds",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05619484"
    },
    {
      "nct_id": "NCT01336517",
      "title": "Evaluation of the Effect of an Ankle Foot Orthoses for Ambulatory Function",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hemiplegia, Spastic"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Kessler Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 20,
      "start_date": "2007-08",
      "completion_date": "2008-12",
      "has_results": false,
      "last_update_posted_date": "2011-04-18",
      "last_synced_at": "2026-07-22T06:07:39.502Z",
      "location_count": 1,
      "location_summary": "West Orange, New Jersey",
      "locations": [
        {
          "city": "West Orange",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01336517"
    },
    {
      "nct_id": "NCT04800484",
      "title": "The Effects of AFO Heel Height and Stiffness on Gait",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Musculoskeletal Injury",
        "Musculoskeletal Diseases",
        "Peripheral Nervous System Diseases"
      ],
      "interventions": [
        {
          "name": "Tall Soft",
          "type": "DEVICE"
        },
        {
          "name": "Tall Firm",
          "type": "DEVICE"
        },
        {
          "name": "Short Soft",
          "type": "DEVICE"
        },
        {
          "name": "Short Firm",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 40,
      "start_date": "2019-11-07",
      "completion_date": "2027-01-01",
      "has_results": false,
      "last_update_posted_date": "2025-12-31",
      "last_synced_at": "2026-07-22T06:07:39.502Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04800484"
    }
  ]
}