{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ankle+Fracture+Surgery&page=2",
    "query": {
      "condition": "Ankle Fracture Surgery",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ankle+Fracture+Surgery&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-28T14:24:24.600Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06078371",
      "title": "Opioid-Free Pain Treatment in Trauma Patients",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Femoral Neck Fractures",
        "Intertrochanteric Fractures",
        "Femoral Shaft Fracture",
        "Distal Femur Fracture",
        "Patella Fracture",
        "Tibial Shaft Fracture with or Without Associated Fibula Fracture",
        "Ankle Fracture (bimalleolar Equivalent, Bimalleolar, or Trimalleolar)",
        "Tibial Pilon Fracture",
        "Talar Head, Neck, Body, or Process Fractures",
        "Calcaneus Fractures",
        "Lisfranc Injuries",
        "Isolated or Multiple Metatarsal Fractures",
        "Phalanx Fractures of the Foot, Single or Multiple",
        "Clavicle Fractures",
        "Proximal Humerus Fractures",
        "Humeral Shaft Fractures",
        "Distal Humerus Fractures (intra or Extra-articular)",
        "Olecranon Fractures",
        "Radial Head or Neck Fractures",
        "Elbow Fractures Involving a Combination of Fractures of the Radius and Uln",
        "Forearm Fractures (both Bone Forearm Fractures, Isolated Ulnar Shaft, Isolated Radial Shaft)",
        "Distal Radius Fractures"
      ],
      "interventions": [
        {
          "name": "Opioid-free pain treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 250,
      "start_date": "2023-11-01",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2024-10-26",
      "last_synced_at": "2026-09-28T14:24:24.600Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06078371"
    },
    {
      "nct_id": "NCT05729542",
      "title": "Comparing Clinical Outcomes of Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Injuries",
        "Syndesmotic Injuries",
        "Ankle Fractures"
      ],
      "interventions": [
        {
          "name": "Arthrex Tightrope",
          "type": "DEVICE"
        },
        {
          "name": "Synthes Fibulink",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 140,
      "start_date": "2021-11-18",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-10",
      "last_synced_at": "2026-09-28T14:24:24.600Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05729542"
    },
    {
      "nct_id": "NCT02950558",
      "title": "Anesthesia for Pain After Ankle Fracture Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Chronic Pain",
        "Ankle Fracture Surgery",
        "Regional Anesthesia"
      ],
      "interventions": [
        {
          "name": "Ropivacaine",
          "type": "DRUG"
        },
        {
          "name": "Nerve block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "University of Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 14,
      "start_date": "2018-05-29",
      "completion_date": "2020-06-19",
      "has_results": true,
      "last_update_posted_date": "2021-07-02",
      "last_synced_at": "2026-09-28T14:24:24.600Z",
      "location_count": 2,
      "location_summary": "Cincinnati, Ohio • West Chester, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "West Chester",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02950558"
    },
    {
      "nct_id": "NCT05445960",
      "title": "Correlation Between Intraoperative Tourniquet Use and Limb pH, Functional Measures and Patient-reported Outcomes After Ankle Fracture Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Fractures",
        "Ankle Fracture - Lateral Malleolus",
        "Ankle Fracture, Bimalleolar",
        "Ankle Fracture, Trimalleolar",
        "Ankle Fracture - Medial Malleolus",
        "Maisonneuve's Fracture",
        "Syndesmotic Injuries",
        "Fibula Fracture"
      ],
      "interventions": [
        {
          "name": "Tourniquet",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 390,
      "start_date": "2021-08-17",
      "completion_date": "2027-03-17",
      "has_results": false,
      "last_update_posted_date": "2025-03-24",
      "last_synced_at": "2026-09-28T14:24:24.600Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05445960"
    },
    {
      "nct_id": "NCT00060970",
      "title": "Evaluating Muscle Function After Ankle Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Muscle Atrophy",
        "Muscle Weakness",
        "Fractures"
      ],
      "interventions": [
        {
          "name": "Physical Therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "1995-09",
      "completion_date": "2000-08",
      "has_results": false,
      "last_update_posted_date": "2005-06-24",
      "last_synced_at": "2026-09-28T14:24:24.600Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00060970"
    },
    {
      "nct_id": "NCT07004764",
      "title": "Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Achilles Tendon Repairs/Reconstructions",
        "Pilon Fracture of Tibia",
        "Tibial Plateau Fracture",
        "Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar)",
        "Calcaneus Fractures",
        "Talus Fracture",
        "Wound Infection Deep",
        "Wound Infection Post-Traumatic",
        "Wound Dehiscence, Surgical"
      ],
      "interventions": [
        {
          "name": "Nitroglycerin Ointment 2%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2026-11",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-31",
      "last_synced_at": "2026-09-28T14:24:24.600Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07004764"
    },
    {
      "nct_id": "NCT07052721",
      "title": "Randomized Study of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Shoulder/Foot Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rotator Cuff Tears",
        "Shoulder Injuries",
        "Hallux Valgus",
        "Ankle Arthropathy",
        "Clavicle Fracture"
      ],
      "interventions": [
        {
          "name": "Experimental Treatment",
          "type": "DEVICE"
        },
        {
          "name": "Sham Comparator",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2025-09-05",
      "completion_date": "2026-06-26",
      "has_results": false,
      "last_update_posted_date": "2026-07-27",
      "last_synced_at": "2026-09-28T14:24:24.600Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07052721"
    },
    {
      "nct_id": "NCT07693933",
      "title": "Biodegradable Magnesium Screws for Unstable Ankle Fracture Surgery",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Fractures",
        "Syndesmotic Injury"
      ],
      "interventions": [
        {
          "name": "RemeOs Magnesium-Based Biodegradable Screw",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 28,
      "start_date": "2026-08",
      "completion_date": "2029-03",
      "has_results": false,
      "last_update_posted_date": "2026-07-27",
      "last_synced_at": "2026-09-28T14:24:24.600Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07693933"
    },
    {
      "nct_id": "NCT06949826",
      "title": "Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain, Postoperative",
        "Ankle Fracture Surgery",
        "Opioid Use Disorder",
        "Opioid Dependence",
        "Opioid Analgesia"
      ],
      "interventions": [
        {
          "name": "Buprenorphine Transdermal System",
          "type": "DRUG"
        },
        {
          "name": "Placebo Patch",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jenna-Leigh Wilson",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2025-04-21",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-04-06",
      "last_synced_at": "2026-09-28T14:24:24.600Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06949826"
    },
    {
      "nct_id": "NCT02480621",
      "title": "Liposomal Bupivacaine With Bupivacaine in Ankle Fracture Open Reduction Internal Fixation (ORIF)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Ankle Fracture"
      ],
      "interventions": [
        {
          "name": "Liposomal Bupivacaine with Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jamaica Hospital Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 84,
      "start_date": "2014-12",
      "completion_date": "2016-08-31",
      "has_results": true,
      "last_update_posted_date": "2017-10-20",
      "last_synced_at": "2026-09-28T14:24:24.600Z",
      "location_count": 1,
      "location_summary": "Jamaica, New York",
      "locations": [
        {
          "city": "Jamaica",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02480621"
    }
  ]
}