{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ankle+Injury&page=2",
    "query": {
      "condition": "Ankle Injury",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ankle+Injury&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T04:07:49.600Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00869180",
      "title": "Diclofenac Patch for Treatment of Acute Pain Due to Mild to Moderate Ankle Sprain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Acute Pain",
        "Ankle Sprain"
      ],
      "interventions": [
        {
          "name": "Diclofenac Sodium",
          "type": "DRUG"
        },
        {
          "name": "Matching Placebo Patch",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cerimon Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "17 Years to 75 Years"
      },
      "enrollment_count": 219,
      "start_date": "2009-02",
      "completion_date": "2009-08",
      "has_results": false,
      "last_update_posted_date": "2010-01-28",
      "last_synced_at": "2026-06-11T04:07:49.600Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00869180"
    },
    {
      "nct_id": "NCT01117909",
      "title": "Effects of Talocrural Joint Mobilizations in the Treatment of Subacute Lateral Ankle Sprains",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Sprain"
      ],
      "interventions": [
        {
          "name": "Mobilization therapy in addition to standard therapy",
          "type": "OTHER"
        },
        {
          "name": "Sham intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 60,
      "start_date": "2010-04",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2011-05-30",
      "last_synced_at": "2026-06-11T04:07:49.600Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01117909"
    },
    {
      "nct_id": "NCT07312032",
      "title": "The Effects of Footplate Stiffness on Foot Loading Within Carbon Fiber Custom Dynamic Orthoses",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Trauma Injury"
      ],
      "interventions": [
        {
          "name": "Carbon Fiber Custom Dynamic Orthosis",
          "type": "DEVICE"
        },
        {
          "name": "Carbon Fiber Footplate",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Jason Wilken",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2025-12-13",
      "completion_date": "2027-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-12-31",
      "last_synced_at": "2026-06-11T04:07:49.600Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07312032"
    },
    {
      "nct_id": "NCT04972578",
      "title": "Comparison of Gait in Syndesmosis Injuries Treated With Screw Fixation vs Suture Button",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Disruption of Ankle Syndesmosis"
      ],
      "interventions": [
        {
          "name": "Suture Button vs Screw Fixation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2021-10-01",
      "completion_date": "2026-01-09",
      "has_results": false,
      "last_update_posted_date": "2026-01-13",
      "last_synced_at": "2026-06-11T04:07:49.600Z",
      "location_count": 3,
      "location_summary": "Bellevue, Nebraska • Omaha, Nebraska",
      "locations": [
        {
          "city": "Bellevue",
          "state": "Nebraska"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04972578"
    },
    {
      "nct_id": "NCT06484712",
      "title": "Electrical Stimulation Effect on Ankle Instability During Walking in Virtual Reality Setup",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Sprains",
        "Ankle Instability"
      ],
      "interventions": [
        {
          "name": "Stochastic Resonance (SR)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Delaware",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 32,
      "start_date": "2024-05-29",
      "completion_date": "2025-01-09",
      "has_results": false,
      "last_update_posted_date": "2025-04-11",
      "last_synced_at": "2026-06-11T04:07:49.600Z",
      "location_count": 1,
      "location_summary": "Newark, Delaware",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06484712"
    },
    {
      "nct_id": "NCT05568784",
      "title": "Straight Leg Raise Continuation",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Quadriceps Muscle Atrophy",
        "Leg Injury"
      ],
      "interventions": [
        {
          "name": "Straight Leg Raise exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Andrews Research & Education Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 100,
      "start_date": "2021-04-11",
      "completion_date": "2024-07-03",
      "has_results": false,
      "last_update_posted_date": "2024-02-21",
      "last_synced_at": "2026-06-11T04:07:49.600Z",
      "location_count": 1,
      "location_summary": "Gulf Breeze, Florida",
      "locations": [
        {
          "city": "Gulf Breeze",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05568784"
    },
    {
      "nct_id": "NCT00950183",
      "title": "Motorized Continuous Cold Therapy Versus Standard Post-op Icing Protocol for Two Foot and Ankle Procedures",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Narcotic Consumption",
        "Pain",
        "Wound Healing",
        "Patient Satisfaction"
      ],
      "interventions": [
        {
          "name": "Iceman® Cold Therapy unit (djOrtho)",
          "type": "DEVICE"
        },
        {
          "name": "Ice",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "OrthoCarolina Research Institute, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 36,
      "start_date": "2007-02",
      "completion_date": "2010-12",
      "has_results": true,
      "last_update_posted_date": "2016-08-22",
      "last_synced_at": "2026-06-11T04:07:49.600Z",
      "location_count": 1,
      "location_summary": "Charlotte, North Carolina",
      "locations": [
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00950183"
    },
    {
      "nct_id": "NCT02032966",
      "title": "Surgical Versus Nonsurgical Treatment of Fibular Fractures: A Prospective Randomized Study",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Fracture",
        "Malleolus Fracture",
        "Medial Malleolus Fracture",
        "Bimalleolar Fracture",
        "Trimalleolar Fracture"
      ],
      "interventions": [
        {
          "name": "Nonsurgical",
          "type": "PROCEDURE"
        },
        {
          "name": "Surgical",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Tennessee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2011-04",
      "completion_date": "2019-12",
      "has_results": false,
      "last_update_posted_date": "2018-11-28",
      "last_synced_at": "2026-06-11T04:07:49.600Z",
      "location_count": 1,
      "location_summary": "Chattanooga, Tennessee",
      "locations": [
        {
          "city": "Chattanooga",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02032966"
    },
    {
      "nct_id": "NCT01639144",
      "title": "Use of Platelet-Rich Plasma (PRP) and Platelet-Poor Plasma (PPP) to Prevent Infection and Delayed Wound Healing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Elective Foot and Ankle Surgery."
      ],
      "interventions": [
        {
          "name": "PRP and PPP",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Gary M. Kiebzak, Ph.D.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 515,
      "start_date": "2012-07",
      "completion_date": "2015-03",
      "has_results": true,
      "last_update_posted_date": "2015-05-22",
      "last_synced_at": "2026-06-11T04:07:49.600Z",
      "location_count": 1,
      "location_summary": "Coral Gables, Florida",
      "locations": [
        {
          "city": "Coral Gables",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01639144"
    },
    {
      "nct_id": "NCT06127316",
      "title": "The Effects of Heel Distraction Height on Foot Loading With Carbon Fiber Custom Dynamic Orthoses",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Lower Limb Injury"
      ],
      "interventions": [
        {
          "name": "Carbon Fiber Custom Dynamic Orthosis (CDO)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2024-08-16",
      "completion_date": "2026-06-01",
      "has_results": false,
      "last_update_posted_date": "2026-01-15",
      "last_synced_at": "2026-06-11T04:07:49.600Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06127316"
    }
  ]
}