{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ankle+Pain&page=2",
    "query": {
      "condition": "Ankle Pain",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ankle+Pain&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T21:02:42.856Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05552430",
      "title": "Virtual Reality for Pain in Acute Orthopedic Injuries",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Injuries",
        "Injury Arm",
        "Injury;Sports",
        "Injury, Knee",
        "Injury Wrist",
        "Injury, Ankle",
        "Injury Foot",
        "Injury, Hand",
        "Injury Finger",
        "Injury Leg"
      ],
      "interventions": [
        {
          "name": "RelieveVRx",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2022-10-17",
      "completion_date": "2023-10-12",
      "has_results": true,
      "last_update_posted_date": "2024-08-22",
      "last_synced_at": "2026-06-10T21:02:42.856Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05552430"
    },
    {
      "nct_id": "NCT06949826",
      "title": "Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain, Postoperative",
        "Ankle Fracture Surgery",
        "Opioid Use Disorder",
        "Opioid Dependence",
        "Opioid Analgesia"
      ],
      "interventions": [
        {
          "name": "Buprenorphine Transdermal System",
          "type": "DRUG"
        },
        {
          "name": "Placebo Patch",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jenna-Leigh Wilson",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2025-04-21",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-04-06",
      "last_synced_at": "2026-06-10T21:02:42.856Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06949826"
    },
    {
      "nct_id": "NCT05285007",
      "title": "Limited Ankle Dorsiflexion and Effect on Single Limb Squats in Individuals With Patellofemoral Pain",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patellofemoral Pain"
      ],
      "interventions": [
        {
          "name": "Mobilization with Movement",
          "type": "OTHER"
        },
        {
          "name": "No mobilization with movement and education",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "59 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 59 Years · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2022-03-02",
      "completion_date": "2026-05",
      "has_results": false,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-06-10T21:02:42.856Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05285007"
    },
    {
      "nct_id": "NCT02480621",
      "title": "Liposomal Bupivacaine With Bupivacaine in Ankle Fracture Open Reduction Internal Fixation (ORIF)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Ankle Fracture"
      ],
      "interventions": [
        {
          "name": "Liposomal Bupivacaine with Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jamaica Hospital Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 84,
      "start_date": "2014-12",
      "completion_date": "2016-08-31",
      "has_results": true,
      "last_update_posted_date": "2017-10-20",
      "last_synced_at": "2026-06-10T21:02:42.856Z",
      "location_count": 1,
      "location_summary": "Jamaica, New York",
      "locations": [
        {
          "city": "Jamaica",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02480621"
    },
    {
      "nct_id": "NCT04164563",
      "title": "Even-Up to Minimize Secondary Site Pain For Ankle Fracture",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthralgia",
        "Trouble Balancing"
      ],
      "interventions": [
        {
          "name": "Even-Up",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2019-11-14",
      "completion_date": "2020-09-10",
      "has_results": true,
      "last_update_posted_date": "2022-10-18",
      "last_synced_at": "2026-06-10T21:02:42.856Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04164563"
    },
    {
      "nct_id": "NCT02285868",
      "title": "ATI Evidence-based Guide Investigating Clinical Services",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Body Region (Arranged Most Common to Least)",
        "Lumbar/SI",
        "Knee",
        "Shoulder",
        "Cervical/Thoracic",
        "Foot/Ankle",
        "Hip",
        "Elbow",
        "Neurological",
        "Vestibular",
        "Pelvic Floor",
        "TMJ",
        "Fibromyalgia",
        "Headaches",
        "Lymphedema"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "ATI Holdings, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 4000000,
      "start_date": "2026-02-24",
      "completion_date": "2029-02-24",
      "has_results": false,
      "last_update_posted_date": "2026-03-05",
      "last_synced_at": "2026-06-10T21:02:42.856Z",
      "location_count": 1,
      "location_summary": "Downers Grove, Illinois",
      "locations": [
        {
          "city": "Downers Grove",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02285868"
    },
    {
      "nct_id": "NCT00351104",
      "title": "Efficacy and Safety of Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Ankle Sprain or Strain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Sprain",
        "Strain"
      ],
      "interventions": [
        {
          "name": "Ketoprofen Topical Patch 20%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "APR Applied Pharma Research s.a.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2006-06",
      "completion_date": "2007-03",
      "has_results": false,
      "last_update_posted_date": "2020-02-19",
      "last_synced_at": "2026-06-10T21:02:42.856Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00351104"
    },
    {
      "nct_id": "NCT01484535",
      "title": "Aspiration for Pain Relief Following Ankle Fracture",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Fracture"
      ],
      "interventions": [
        {
          "name": "Ankle Aspiration",
          "type": "PROCEDURE"
        },
        {
          "name": "Ankle aspiration Standard Anterolateral",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 130,
      "start_date": "2011-09",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2015-07-17",
      "last_synced_at": "2026-06-10T21:02:42.856Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01484535"
    },
    {
      "nct_id": "NCT04520854",
      "title": "Telehealth Delivered Physical Rehabilitation for an Ankle Sprain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Sprains",
        "Telerehabilitation",
        "Analgesic, Opioid",
        "Analgesics, Non-narcotic",
        "Anti-Inflammatory Agents, Non-Steroidal",
        "Implementation Science",
        "Acute Pain",
        "Quality of Life"
      ],
      "interventions": [
        {
          "name": "Telehealth Protocol",
          "type": "OTHER"
        },
        {
          "name": "Usual Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Kyle Kosik",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "15 Years to 35 Years"
      },
      "enrollment_count": 21,
      "start_date": "2021-01-01",
      "completion_date": "2025-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-07-28",
      "last_synced_at": "2026-06-10T21:02:42.856Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04520854"
    },
    {
      "nct_id": "NCT02629731",
      "title": "Orthotic Dose Response Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Osteoarthritis",
        "Flat Foot or Pes Planus"
      ],
      "interventions": [
        {
          "name": "custom orthoses with varying degrees of hindfoot posting",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 35,
      "start_date": "2016-07-01",
      "completion_date": "2023-12-29",
      "has_results": false,
      "last_update_posted_date": "2024-06-21",
      "last_synced_at": "2026-06-10T21:02:42.856Z",
      "location_count": 2,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02629731"
    }
  ]
}