{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ankle+Pathology",
    "query": {
      "condition": "Ankle Pathology"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 85,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ankle+Pathology&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T20:50:01.490Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00060970",
      "title": "Evaluating Muscle Function After Ankle Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Muscle Atrophy",
        "Muscle Weakness",
        "Fractures"
      ],
      "interventions": [
        {
          "name": "Physical Therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "1995-09",
      "completion_date": "2000-08",
      "has_results": false,
      "last_update_posted_date": "2005-06-24",
      "last_synced_at": "2026-07-22T20:50:01.490Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00060970"
    },
    {
      "nct_id": "NCT01550094",
      "title": "A Comparison of Two Injection Locations in Obese Patients Having Lower Leg/Foot Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Strain of Muscle and/or Tendon of Lower Leg",
        "Fracture of Lower Leg",
        "Crushing Injury of Lower Leg",
        "Fracture Malunion - Ankle and/ or Foot",
        "Complete Tear, Ankle and/or Foot Ligament",
        "Pathological Fracture - Ankle and/or Foot",
        "Loose Body in Joint of Ankle and/or Foot"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Jose Soberon, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2012-03",
      "completion_date": "2015-10",
      "has_results": false,
      "last_update_posted_date": "2015-10-14",
      "last_synced_at": "2026-07-22T20:50:01.490Z",
      "location_count": 1,
      "location_summary": "New Orleans, Louisiana",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01550094"
    },
    {
      "nct_id": "NCT02285868",
      "title": "ATI Evidence-based Guide Investigating Clinical Services",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Body Region (Arranged Most Common to Least)",
        "Lumbar/SI",
        "Knee",
        "Shoulder",
        "Cervical/Thoracic",
        "Foot/Ankle",
        "Hip",
        "Elbow",
        "Neurological",
        "Vestibular",
        "Pelvic Floor",
        "TMJ",
        "Fibromyalgia",
        "Headaches",
        "Lymphedema"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "ATI Holdings, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 4000000,
      "start_date": "2026-02-24",
      "completion_date": "2029-02-24",
      "has_results": false,
      "last_update_posted_date": "2026-03-05",
      "last_synced_at": "2026-07-22T20:50:01.490Z",
      "location_count": 1,
      "location_summary": "Downers Grove, Illinois",
      "locations": [
        {
          "city": "Downers Grove",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02285868"
    },
    {
      "nct_id": "NCT01336517",
      "title": "Evaluation of the Effect of an Ankle Foot Orthoses for Ambulatory Function",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hemiplegia, Spastic"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Kessler Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 20,
      "start_date": "2007-08",
      "completion_date": "2008-12",
      "has_results": false,
      "last_update_posted_date": "2011-04-18",
      "last_synced_at": "2026-07-22T20:50:01.490Z",
      "location_count": 1,
      "location_summary": "West Orange, New Jersey",
      "locations": [
        {
          "city": "West Orange",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01336517"
    },
    {
      "nct_id": "NCT06284525",
      "title": "Ankle Assistance and Resistance in Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Sarcopenia"
      ],
      "interventions": [
        {
          "name": "Ankle resistance and biofeedback",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Northern Arizona University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "65 Years to 85 Years"
      },
      "enrollment_count": 9,
      "start_date": "2023-02-01",
      "completion_date": "2024-02-20",
      "has_results": true,
      "last_update_posted_date": "2025-10-01",
      "last_synced_at": "2026-07-22T20:50:01.490Z",
      "location_count": 1,
      "location_summary": "Flagstaff, Arizona",
      "locations": [
        {
          "city": "Flagstaff",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06284525"
    },
    {
      "nct_id": "NCT05939843",
      "title": "Brief Mindfulness for Foot and Ankle Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Pain Coping Information",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mindfulness Practice (alone)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mindfulness Introduction + Mindfulness Practice",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pain Introduction + Mindfulness Introduction + Mindfulness Practice",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 28,
      "start_date": "2023-07-12",
      "completion_date": "2023-07-27",
      "has_results": false,
      "last_update_posted_date": "2025-06-19",
      "last_synced_at": "2026-07-22T20:50:01.490Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05939843"
    },
    {
      "nct_id": "NCT07212114",
      "title": "Efficacy of EXPAREL vs. Bupivacaine",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Total Ankle Arthroplasty",
        "Postsurgical Analgesia"
      ],
      "interventions": [
        {
          "name": "EXPAREL",
          "type": "DRUG"
        },
        {
          "name": "0.25% bupivacaine (HCl): 50 ml",
          "type": "DRUG"
        },
        {
          "name": "0.25% bupivacaine (HCl): 30 ml",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 104,
      "start_date": "2025-11-17",
      "completion_date": "2029-08",
      "has_results": false,
      "last_update_posted_date": "2026-02-23",
      "last_synced_at": "2026-07-22T20:50:01.490Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07212114"
    },
    {
      "nct_id": "NCT06264596",
      "title": "Epinephrine in Irrigation Fluid for Visualization During Ankle Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Intraoperative Bleeding"
      ],
      "interventions": [
        {
          "name": "Epinephrine",
          "type": "DRUG"
        },
        {
          "name": "Normal Saline irrigation fluid",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "The Guthrie Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2024-08",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2024-10-15",
      "last_synced_at": "2026-07-22T20:50:01.490Z",
      "location_count": 1,
      "location_summary": "Sayre, Pennsylvania",
      "locations": [
        {
          "city": "Sayre",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06264596"
    },
    {
      "nct_id": "NCT02950558",
      "title": "Anesthesia for Pain After Ankle Fracture Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Chronic Pain",
        "Ankle Fracture Surgery",
        "Regional Anesthesia"
      ],
      "interventions": [
        {
          "name": "Ropivacaine",
          "type": "DRUG"
        },
        {
          "name": "Nerve block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "University of Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 14,
      "start_date": "2018-05-29",
      "completion_date": "2020-06-19",
      "has_results": true,
      "last_update_posted_date": "2021-07-02",
      "last_synced_at": "2026-07-22T20:50:01.490Z",
      "location_count": 2,
      "location_summary": "Cincinnati, Ohio • West Chester, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "West Chester",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02950558"
    },
    {
      "nct_id": "NCT05364606",
      "title": "Patient Specific Talus Spacer Post Approval Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Avascular Necrosis of the Talus"
      ],
      "interventions": [
        {
          "name": "Patient Specific Talus Spacer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Paragon 28",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2022-07-08",
      "completion_date": "2029-11-30",
      "has_results": false,
      "last_update_posted_date": "2024-11-07",
      "last_synced_at": "2026-07-22T20:50:01.490Z",
      "location_count": 6,
      "location_summary": "Santa Rosa, California • Fort Wayne, Indiana • Baltimore, Maryland + 3 more",
      "locations": [
        {
          "city": "Santa Rosa",
          "state": "California"
        },
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Morrisville",
          "state": "North Carolina"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05364606"
    }
  ]
}