{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anterior+Cruciate+Ligament+%28ACL%29+Tears",
    "query": {
      "condition": "Anterior Cruciate Ligament (ACL) Tears"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 59,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anterior+Cruciate+Ligament+%28ACL%29+Tears&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-03T17:13:33.240Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04572256",
      "title": "MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "ACL Injury",
        "Meniscus Tear",
        "Post-traumatic Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Montelukast",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Austin V Stone",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "25 Years to 50 Years"
      },
      "enrollment_count": 30,
      "start_date": "2021-02-01",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-06-10",
      "last_synced_at": "2026-10-03T17:13:33.240Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04572256"
    },
    {
      "nct_id": "NCT02664545",
      "title": "Bridge-Enhanced ACL Repair vs ACL Reconstruction",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Tear"
      ],
      "interventions": [
        {
          "name": "BEAR Scaffold",
          "type": "DEVICE"
        },
        {
          "name": "Tendon Graft",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Miach Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "14 Years to 35 Years"
      },
      "enrollment_count": 100,
      "start_date": "2016-04",
      "completion_date": "2028-05-31",
      "has_results": true,
      "last_update_posted_date": "2025-12-30",
      "last_synced_at": "2026-10-03T17:13:33.240Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02664545"
    },
    {
      "nct_id": "NCT07115056",
      "title": "Extended Oral Tranexamic Acid After Anterior Cruciate Ligament Reconstruction",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "ACL Injury",
        "ACL Tears",
        "ACL Surgery"
      ],
      "interventions": [
        {
          "name": "Tranexamic Acid (TXA)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Campbell Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "22 Years",
        "sex": "ALL",
        "summary": "14 Years to 22 Years"
      },
      "enrollment_count": 0,
      "start_date": "2026-04-01",
      "completion_date": "2029-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-03",
      "last_synced_at": "2026-10-03T17:13:33.240Z",
      "location_count": 6,
      "location_summary": "Evanston, Illinois • Chesterfield, Missouri • Durham, North Carolina + 3 more",
      "locations": [
        {
          "city": "Evanston",
          "state": "Illinois"
        },
        {
          "city": "Chesterfield",
          "state": "Missouri"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07115056"
    },
    {
      "nct_id": "NCT04374968",
      "title": "Use of Blood Flow Restriction Therapy Following ACL Tear",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Tear",
        "Knee Injuries",
        "Sport Injury"
      ],
      "interventions": [
        {
          "name": "Blood flood restriction cuff",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 50,
      "start_date": "2020-07-28",
      "completion_date": "2022-05-01",
      "has_results": false,
      "last_update_posted_date": "2023-07-19",
      "last_synced_at": "2026-10-03T17:13:33.240Z",
      "location_count": 1,
      "location_summary": "West Bloomfield, Michigan",
      "locations": [
        {
          "city": "West Bloomfield",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04374968"
    },
    {
      "nct_id": "NCT03243162",
      "title": "Improving ACL Reconstruction Outcomes: CBPT",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL Injury",
        "ACL - Anterior Cruciate Ligament Rupture",
        "ACL Sprain",
        "ACL Tear"
      ],
      "interventions": [
        {
          "name": "CBPT-ACLR",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Education",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "14 Years to 35 Years"
      },
      "enrollment_count": 90,
      "start_date": "2017-07-01",
      "completion_date": "2020-04-17",
      "has_results": false,
      "last_update_posted_date": "2020-05-20",
      "last_synced_at": "2026-10-03T17:13:33.240Z",
      "location_count": 2,
      "location_summary": "Garfield Heights, Ohio • Nashville, Tennessee",
      "locations": [
        {
          "city": "Garfield Heights",
          "state": "Ohio"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03243162"
    },
    {
      "nct_id": "NCT03497780",
      "title": "Longitudinal Assessment of Cartilage Injury and Remodeling After Anterior Cruciate Ligament Rupture and Reconstruction:",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "ACL - Anterior Cruciate Ligament Rupture",
        "ACL Injury",
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Anterior cruciate ligament reconstruction",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 13,
      "start_date": "2018-11-08",
      "completion_date": "2021-03-25",
      "has_results": false,
      "last_update_posted_date": "2023-04-05",
      "last_synced_at": "2026-10-03T17:13:33.240Z",
      "location_count": 2,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03497780"
    },
    {
      "nct_id": "NCT04682392",
      "title": "ACL Bone Health and Loading Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL Tear"
      ],
      "interventions": [
        {
          "name": "Delfi's PTS Personalized Tourniquet System for Blood Flow Restriction Group",
          "type": "DEVICE"
        },
        {
          "name": "Standard ACL rehab",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Candice Dunkin, MS, LAT, ATC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "22 Years",
        "sex": "ALL",
        "summary": "16 Years to 22 Years"
      },
      "enrollment_count": 19,
      "start_date": "2021-02-17",
      "completion_date": "2025-05-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-10-03T17:13:33.240Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04682392"
    },
    {
      "nct_id": "NCT06340932",
      "title": "Impact of Opioid Avoidance Protocol for ACL Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "ACL Tear",
        "Post Operative Pain"
      ],
      "interventions": [
        {
          "name": "Iovera",
          "type": "DEVICE"
        },
        {
          "name": "Celecoxib",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "Oxycodone",
          "type": "DRUG"
        },
        {
          "name": "Tramadol",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine Hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen 500Mg Cap",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Matthew Varacallo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "15 Years and older"
      },
      "enrollment_count": 32,
      "start_date": "2024-04-27",
      "completion_date": "2025-02-01",
      "has_results": false,
      "last_update_posted_date": "2025-03-07",
      "last_synced_at": "2026-10-03T17:13:33.240Z",
      "location_count": 1,
      "location_summary": "DuBois, Pennsylvania",
      "locations": [
        {
          "city": "DuBois",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06340932"
    },
    {
      "nct_id": "NCT01148784",
      "title": "Comparison of Doubled Quadrupled Versus Quadrupled Allograft Tissue Constructs for Anterior Cruciate Ligament (ACL) Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament",
        "Injury"
      ],
      "interventions": [
        {
          "name": "ACL reconstruction",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 102,
      "start_date": "2010-06",
      "completion_date": "2014-04-05",
      "has_results": false,
      "last_update_posted_date": "2019-07-11",
      "last_synced_at": "2026-10-03T17:13:33.240Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01148784"
    },
    {
      "nct_id": "NCT03983941",
      "title": "IPACK Versus Popliteal Sciatic Nerve Block in ACL Reconstruction",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Tear"
      ],
      "interventions": [
        {
          "name": "Ropivacaine injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sujana Dontukurthy",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "Up to 21 Years"
      },
      "enrollment_count": 7,
      "start_date": "2019-08-30",
      "completion_date": "2019-11-07",
      "has_results": true,
      "last_update_posted_date": "2021-09-16",
      "last_synced_at": "2026-10-03T17:13:33.240Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03983941"
    }
  ]
}