{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anti-obesity+Agents", "query": { "condition": "Anti-obesity Agents" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 20, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anti-obesity+Agents&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-06-26T06:33:05.940Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05975580", "title": "Pharmacotherapy in Conjunction With Lifestyle Counseling for Management of Weight Regain After Bariatric Surgery", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Obesity" ], "interventions": [ { "name": "Topiramate", "type": "DRUG" }, { "name": "Phentermine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, Irvine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 120, "start_date": "2023-08-29", "completion_date": "2028-01-31", "has_results": false, "last_update_posted_date": "2026-06-09", "last_synced_at": "2026-06-26T06:33:05.940Z", "location_count": 1, "location_summary": "Orange, California", "locations": [ { "city": "Orange", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05975580" }, { "nct_id": "NCT01739192", "title": "A Novel Anti-Obesity Drug Combination as a Pharmacotherapy for Cocaine Dependence", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Cocaine Use Disorders" ], "interventions": [ { "name": "Bupropion", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Craig Rush", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 34, "start_date": "2013-01", "completion_date": "2018-06", "has_results": false, "last_update_posted_date": "2018-06-26", "last_synced_at": "2026-06-26T06:33:05.940Z", "location_count": 1, "location_summary": "Lexington, Kentucky", "locations": [ { "city": "Lexington", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT01739192" }, { "nct_id": "NCT03779048", "title": "Use of Medication to Improve Weight Loss in Suboptimal Early Responders to Behavioral Treatment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Obesity" ], "interventions": [ { "name": "Behavioral Treatment", "type": "BEHAVIORAL" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Phentermine 15 MG", "type": "DRUG" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "21 Years to 70 Years" }, "enrollment_count": 147, "start_date": "2019-07-15", "completion_date": "2022-05-25", "has_results": true, "last_update_posted_date": "2025-03-11", "last_synced_at": "2026-06-26T06:33:05.940Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT03779048" }, { "nct_id": "NCT01728116", "title": "Safety and Efficacy of EndoBarrier in Subjects With Type 2 Diabetes Who Are Obese", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Type 2 Diabetes", "Obesity" ], "interventions": [ { "name": "EndoBarrier", "type": "DEVICE" }, { "name": "Sham Procedure", "type": "PROCEDURE" } ], "intervention_types": [ "DEVICE", "PROCEDURE" ], "sponsor": "Morphic Medical Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 325, "start_date": "2012-12", "completion_date": "2016-02", "has_results": true, "last_update_posted_date": "2017-02-01", "last_synced_at": "2026-06-26T06:33:05.940Z", "location_count": 25, "location_summary": "Birmingham, Alabama • Scottsdale, Arizona • Little Rock, Arkansas + 20 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Los Angeles", "state": "California" }, { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01728116" }, { "nct_id": "NCT00650806", "title": "A Study of the Safety and Effectiveness of Canagliflozin (JNJ-28431754) in Promoting Weight Loss in Overweight and Obese Patients Who do Not Have Diabetes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Obesity" ], "interventions": [ { "name": "Canagliflozin (JNJ-28431754)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 376, "start_date": "2008-05", "completion_date": "2008-09", "has_results": true, "last_update_posted_date": "2013-05-24", "last_synced_at": "2026-06-26T06:33:05.940Z", "location_count": 35, "location_summary": "Hot Springs, Arkansas • Walnut Creek, California • Westlake Village, California + 32 more", "locations": [ { "city": "Hot Springs", "state": "Arkansas" }, { "city": "Walnut Creek", "state": "California" }, { "city": "Westlake Village", "state": "California" }, { "city": "Destin", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00650806" }, { "nct_id": "NCT00402077", "title": "A Study to Examine the Safety, Tolerability, and Body Weight Effect of Pramlintide Alone and in Combination With Oral Antiobesity Agents in Overweight and Obese Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Overweight", "Obesity" ], "interventions": [ { "name": "pramlintide acetate", "type": "DRUG" }, { "name": "sibutramine", "type": "DRUG" }, { "name": "phentermine", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 258, "start_date": "2006-11", "completion_date": "2007-08", "has_results": false, "last_update_posted_date": "2015-03-06", "last_synced_at": "2026-06-26T06:33:05.940Z", "location_count": 16, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Chula Vista, California + 13 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Chula Vista", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00402077" }, { "nct_id": "NCT07387796", "title": "Clinical and Neurobehavioral Changes With Weight Loss Drug Discontinuation and Reinitiation", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Drug Discontinuation", "Substance Use Disorders", "Eating Behavior Changes", "Tirzepatide" ], "interventions": [ { "name": "Discontinuation and Reinitiation of Tirzepatide", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "The University of Texas at Dallas", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 40, "start_date": "2026-06", "completion_date": "2029-02", "has_results": false, "last_update_posted_date": "2026-05-29", "last_synced_at": "2026-06-26T06:33:05.940Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07387796" }, { "nct_id": "NCT06171152", "title": "Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues", "overall_status": "SUSPENDED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Multiple Sclerosis", "Long COVID", "Long Covid19", "Obese", "Obesity", "Obesity, Morbid", "Acute Leukemia in Remission" ], "interventions": [ { "name": "Liraglutide Pen Injector [Saxenda]", "type": "DRUG" }, { "name": "Medication Diary", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "40 Years", "sex": "ALL", "summary": "18 Years to 40 Years" }, "enrollment_count": 30, "start_date": "2024-01-26", "completion_date": "2027-10-01", "has_results": false, "last_update_posted_date": "2026-03-30", "last_synced_at": "2026-06-26T06:33:05.940Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT06171152" }, { "nct_id": "NCT00044187", "title": "The Assessment of a Weight-Gain Agent for the Treatment of Olanzapine-Associated Anti-Obesity Agent in Patients With Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder, and Bipolar I Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Schizophrenia", "Psychotic Disorders", "Bipolar Disorder" ], "interventions": [ { "name": "Sibutramine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 130, "start_date": "2001-04", "completion_date": "2003-09", "has_results": false, "last_update_posted_date": "2006-07-19", "last_synced_at": "2026-06-26T06:33:05.940Z", "location_count": 16, "location_summary": "El Centro, California • Jacksonville, Florida • Miami, Florida + 13 more", "locations": [ { "city": "El Centro", "state": "California" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Boise", "state": "Idaho" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00044187" }, { "nct_id": "NCT05215847", "title": "Study to Evaluate ARD-101 in Adults Receiving Bariatric Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Bariatric Surgery", "Obesity", "Weight Gain" ], "interventions": [ { "name": "ARD-101", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Aardvark Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 12, "start_date": "2022-03-01", "completion_date": "2023-02-03", "has_results": true, "last_update_posted_date": "2025-02-11", "last_synced_at": "2026-06-26T06:33:05.940Z", "location_count": 1, "location_summary": "San Diego, California", "locations": [ { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05215847" } ] }