{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anxiety+Depression&page=42",
    "query": {
      "condition": "Anxiety Depression",
      "page": 42
    },
    "page_size": 10
  },
  "pagination": {
    "page": 42,
    "page_size": 10,
    "total_count": 1311,
    "total_pages": 132,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anxiety+Depression&page=43&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anxiety+Depression&page=41&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-27T20:32:22.841Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02445937",
      "title": "PARTNER II: Improving Patient and Family Centered Care in Advanced Critical Illness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety",
        "Depression"
      ],
      "interventions": [
        {
          "name": "PARTNER II",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 848,
      "start_date": "2015-06-01",
      "completion_date": "2019-09-18",
      "has_results": false,
      "last_update_posted_date": "2019-10-15",
      "last_synced_at": "2026-10-27T20:32:22.841Z",
      "location_count": 2,
      "location_summary": "Erie, Pennsylvania • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Erie",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02445937"
    },
    {
      "nct_id": "NCT06820723",
      "title": "A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Depression",
        "Anxiety",
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "CYB003",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2026-11-01",
      "completion_date": "2028-11",
      "has_results": false,
      "last_update_posted_date": "2026-10-20",
      "last_synced_at": "2026-10-27T20:32:22.841Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06820723"
    },
    {
      "nct_id": "NCT03609450",
      "title": "Integrating Mindfulness Into the Patient-Centered Medical Home (Phase 3)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Anxiety Disorders",
        "Stress Related Disorder",
        "Adjustment Disorders",
        "Chronic Illness"
      ],
      "interventions": [
        {
          "name": "Mindfulness Training for Primary Care",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Low-Dose Comparator",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Cambridge Health Alliance",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 96,
      "start_date": "2019-01-30",
      "completion_date": "2020-08-01",
      "has_results": false,
      "last_update_posted_date": "2020-11-20",
      "last_synced_at": "2026-10-27T20:32:22.841Z",
      "location_count": 1,
      "location_summary": "Somerville, Massachusetts",
      "locations": [
        {
          "city": "Somerville",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03609450"
    },
    {
      "nct_id": "NCT03965897",
      "title": "Preventing Persistent Post-Surgical Pain and Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain",
        "Function",
        "Anxiety",
        "Depression",
        "Arthroplasty, Replacement, Knee",
        "Veterans"
      ],
      "interventions": [
        {
          "name": "Acceptance and Commitment Therapy (ACT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Attention Control (AC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 402,
      "start_date": "2019-07-29",
      "completion_date": "2024-01-30",
      "has_results": true,
      "last_update_posted_date": "2026-05-06",
      "last_synced_at": "2026-10-27T20:32:22.841Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03965897"
    },
    {
      "nct_id": "NCT00438685",
      "title": "Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Substance-Related Disorders",
        "Depressive Disorder",
        "Anxiety Disorder"
      ],
      "interventions": [
        {
          "name": "Outpatient MST/OPTION-A",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Services",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "12 Years to 17 Years"
      },
      "enrollment_count": 40,
      "start_date": "2004-10",
      "completion_date": "2010-09",
      "has_results": false,
      "last_update_posted_date": "2018-06-14",
      "last_synced_at": "2026-10-27T20:32:22.841Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00438685"
    },
    {
      "nct_id": "NCT05466851",
      "title": "An Exploratory Study Examining Biopsychosocial Markers of Anxiety and Depression",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Depression",
        "Anxiety Disorders",
        "Stress Related Disorder"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Singula Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 200,
      "start_date": "2023-03-01",
      "completion_date": "2032-03-31",
      "has_results": false,
      "last_update_posted_date": "2024-04-17",
      "last_synced_at": "2026-10-27T20:32:22.841Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05466851"
    },
    {
      "nct_id": "NCT00016731",
      "title": "Adolescence, Puberty, and Emotion Regulation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mood Disorder",
        "Neurobehavioral Manifestation",
        "Healthy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "8 Years to 55 Years"
      },
      "enrollment_count": 300,
      "start_date": "2001-05-29",
      "completion_date": "2017-10-18",
      "has_results": false,
      "last_update_posted_date": "2019-12-17",
      "last_synced_at": "2026-10-27T20:32:22.841Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00016731"
    },
    {
      "nct_id": "NCT02656641",
      "title": "Using the PHQ-9 and GAD-7 as Feedback Instruments in Brief Psychotherapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depressive Symptoms",
        "Anxiety States, Neurotic"
      ],
      "interventions": [
        {
          "name": "Continuous Client Feedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Continuous Self Feedback",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Christiana Care Health Services",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 81,
      "start_date": "2015-11",
      "completion_date": "2016-08-31",
      "has_results": false,
      "last_update_posted_date": "2017-07-19",
      "last_synced_at": "2026-10-27T20:32:22.841Z",
      "location_count": 1,
      "location_summary": "Wilmington, Delaware",
      "locations": [
        {
          "city": "Wilmington",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02656641"
    },
    {
      "nct_id": "NCT05455905",
      "title": "Voice Biomarkers Predictive of Depression and Anxiety",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Depression, Anxiety",
        "Healthy",
        "Mental Health Wellness 1"
      ],
      "interventions": [
        {
          "name": "Patient Health Questionnaire-9",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Generalized Anxiety Disorder-7",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Hamilton Depression Rating Scale",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Hamilton Anxiety Rating Scale",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Kintsugi Mindful Wellness, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 19533,
      "start_date": "2021-09-14",
      "completion_date": "2022-09-11",
      "has_results": false,
      "last_update_posted_date": "2022-09-15",
      "last_synced_at": "2026-10-27T20:32:22.841Z",
      "location_count": 1,
      "location_summary": "Berkeley, California",
      "locations": [
        {
          "city": "Berkeley",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05455905"
    },
    {
      "nct_id": "NCT06789731",
      "title": "Mindfulness-Based Interventions Targeting First-Generation College Student Retention in Rural Environments",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "Mindfulness Meditation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Psychoeducation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of South Dakota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 64,
      "start_date": "2025-01-01",
      "completion_date": "2026-08-24",
      "has_results": false,
      "last_update_posted_date": "2026-09-03",
      "last_synced_at": "2026-10-27T20:32:22.841Z",
      "location_count": 1,
      "location_summary": "Sioux Falls, South Dakota",
      "locations": [
        {
          "city": "Sioux Falls",
          "state": "South Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06789731"
    }
  ]
}