{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anxiety+and+Distress",
    "query": {
      "condition": "Anxiety and Distress"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 103,
    "total_pages": 11,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Anxiety+and+Distress&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T03:09:04.575Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03662698",
      "title": "Effect of Guided Imagery for Radiotherapy-Related Distress in Patients With Head and Neck Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Head and Neck Cancer"
      ],
      "interventions": [
        {
          "name": "Guided Imagery",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Treatment as Usual",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 57,
      "start_date": "2018-10-12",
      "completion_date": "2021-01-08",
      "has_results": true,
      "last_update_posted_date": "2025-03-13",
      "last_synced_at": "2026-07-24T03:09:04.575Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03662698"
    },
    {
      "nct_id": "NCT03904186",
      "title": "Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Human Immunodeficiency Virus",
        "Smoking Cessation",
        "Smoking, Cigarette",
        "Smoking",
        "Anxiety",
        "Depression",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "QUIT",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Time-Matched Control (TM)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 131,
      "start_date": "2019-12-19",
      "completion_date": "2025-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-02-09",
      "last_synced_at": "2026-07-24T03:09:04.575Z",
      "location_count": 3,
      "location_summary": "Boston, Massachusetts • Houston, Texas",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03904186"
    },
    {
      "nct_id": "NCT05981794",
      "title": "Heating Pad for in Office Cystoscopy and Urodynamic Testing",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety",
        "Pain",
        "Distress, Emotional"
      ],
      "interventions": [
        {
          "name": "Electrical heating pad",
          "type": "DEVICE"
        },
        {
          "name": "Sham heating pad",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2025-01",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2025-05-23",
      "last_synced_at": "2026-07-24T03:09:04.575Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05981794"
    },
    {
      "nct_id": "NCT02986152",
      "title": "Cancer Distress Coach Mobile App Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Posttraumatic Stress Disorder",
        "Cancer"
      ],
      "interventions": [
        {
          "name": "Cancer Distress Coach Mobile App",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 569,
      "start_date": "2017-06-01",
      "completion_date": "2019-04-13",
      "has_results": false,
      "last_update_posted_date": "2019-11-26",
      "last_synced_at": "2026-07-24T03:09:04.575Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02986152"
    },
    {
      "nct_id": "NCT05712057",
      "title": "Neurostimulation Versus Therapy for Problems With Emotions",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Emotion Regulation",
        "Mood Disorders",
        "Stress Disorder",
        "Anxiety Disorders",
        "OCD",
        "Impulse Control Disorder",
        "Eating Disorders",
        "Emotional Dysfunction",
        "Emotional Instability",
        "Emotional Distress",
        "Emotional Maladjustment",
        "Emotional Impulsivity",
        "Obsessive-Compulsive Disorder",
        "Emotion Dysregulation",
        "Borderline Personality Disorder"
      ],
      "interventions": [
        {
          "name": "Repetitive Transcranial Magnetic Stimulation (rTMS)",
          "type": "DEVICE"
        },
        {
          "name": "electrical scalp stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Cognitive Restructuring",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Emotional Awareness Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 240,
      "start_date": "2023-05-15",
      "completion_date": "2027-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-04",
      "last_synced_at": "2026-07-24T03:09:04.575Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05712057"
    },
    {
      "nct_id": "NCT04953806",
      "title": "The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical Activity",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "COPD",
        "Depression",
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "Step-CBT",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2021-11-02",
      "completion_date": "2026-10-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-03",
      "last_synced_at": "2026-07-24T03:09:04.575Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04953806"
    },
    {
      "nct_id": "NCT05625360",
      "title": "REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Postoperative Pain, Acute",
        "Postoperative Depression",
        "Anxiety",
        "Sleep Disturbance",
        "Malignant Female Reproductive System Neoplasm"
      ],
      "interventions": [
        {
          "name": "eHealth Mindful Movement and Breathing",
          "type": "OTHER"
        },
        {
          "name": "Life Impacts Reflection",
          "type": "OTHER"
        },
        {
          "name": "PROMIS Questionnaires",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 160,
      "start_date": "2023-06-13",
      "completion_date": "2026-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-15",
      "last_synced_at": "2026-07-24T03:09:04.575Z",
      "location_count": 2,
      "location_summary": "Charlotte, North Carolina • Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05625360"
    },
    {
      "nct_id": "NCT04892160",
      "title": "Distracting Through Procedural Pain and Distress",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Illness",
        "Hematologic Malignancy",
        "Bone Marrow Transplant Infection",
        "Oncology",
        "Sickle Cell Disease"
      ],
      "interventions": [
        {
          "name": "Guided Imagery",
          "type": "OTHER"
        },
        {
          "name": "Virtual Reality",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "8 Years to 25 Years"
      },
      "enrollment_count": 67,
      "start_date": "2018-02-15",
      "completion_date": "2019-04-29",
      "has_results": false,
      "last_update_posted_date": "2021-05-19",
      "last_synced_at": "2026-07-24T03:09:04.575Z",
      "location_count": 2,
      "location_summary": "Milwaukee, Wisconsin • Wauwatosa, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        },
        {
          "city": "Wauwatosa",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04892160"
    },
    {
      "nct_id": "NCT01084694",
      "title": "Caregiver Burden and Distress in Hematopoeitic Stem Cell Transplant",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Depression",
        "Anxiety",
        "Fatigue",
        "Distress"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Northside Hospital, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 100,
      "start_date": "2010-04-19",
      "completion_date": "2018-03-30",
      "has_results": true,
      "last_update_posted_date": "2020-01-07",
      "last_synced_at": "2026-07-24T03:09:04.575Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01084694"
    },
    {
      "nct_id": "NCT06625437",
      "title": "ACT for HIV-Positive Men",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress",
        "Anxiety",
        "Mental Disorder",
        "Distress-based Psychopathology"
      ],
      "interventions": [
        {
          "name": "Acceptance and commitment therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 1,
      "start_date": "2025-01-15",
      "completion_date": "2026-04-16",
      "has_results": false,
      "last_update_posted_date": "2026-04-20",
      "last_synced_at": "2026-07-24T03:09:04.575Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06625437"
    }
  ]
}