{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Aortic+Stenosis+Disease",
    "query": {
      "condition": "Aortic Stenosis Disease"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 340,
    "total_pages": 34,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Aortic+Stenosis+Disease&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T14:43:36.794Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00703443",
      "title": "The Genetics of Cardiomyopathy and Heart Failure",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dilated Cardiomyopathy",
        "Hypertrophic Cardiomyopathy",
        "Mitochondrial Cardiomyopathy",
        "Noncompaction Cardiomyopathy",
        "Restrictive Cardiomyopathy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 0,
      "start_date": "2007-04",
      "completion_date": "2007-04",
      "has_results": false,
      "last_update_posted_date": "2021-01-25",
      "last_synced_at": "2026-06-10T14:43:36.794Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00703443"
    },
    {
      "nct_id": "NCT01225978",
      "title": "Refining Information Technology Support for Genetics in Medicine",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypertrophic Cardiomyopathy",
        "Hearing Loss",
        "Cancer"
      ],
      "interventions": [
        {
          "name": "GeneInsight Clinic (GIC)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 40,
      "start_date": "2009-09",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2014-01-24",
      "last_synced_at": "2026-06-10T14:43:36.794Z",
      "location_count": 8,
      "location_summary": "Boston, Massachusetts • Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01225978"
    },
    {
      "nct_id": "NCT04722250",
      "title": "SMall Annuli Randomized To Evolut™ or SAPIEN™ Trial",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Symptomatic Aortic Stenosis",
        "Aortic Valve Stenosis",
        "Aortic Valve Replacement"
      ],
      "interventions": [
        {
          "name": "Medtronic Evolut PRO, Evolut PRO+ or Evolut FX (where commercially available) TAV Systems",
          "type": "DEVICE"
        },
        {
          "name": "Edwards SAPIEN 3 or SAPIEN 3 Ultra THV Systems",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Cardiovascular",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1103,
      "start_date": "2021-04-02",
      "completion_date": "2027-12",
      "has_results": true,
      "last_update_posted_date": "2026-06-02",
      "last_synced_at": "2026-06-10T14:43:36.794Z",
      "location_count": 61,
      "location_summary": "La Jolla, California • Los Angeles, California • San Francisco, California + 47 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Thousand Oaks",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04722250"
    },
    {
      "nct_id": "NCT05357404",
      "title": "Age and Sex-Specific PREValence of AcqUirEd VALVular Heart DiseasE",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Valvular Heart Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Cardiovascular Research Foundation, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "65 Years to 85 Years"
      },
      "enrollment_count": 2870,
      "start_date": "2022-04-21",
      "completion_date": "2025-04",
      "has_results": false,
      "last_update_posted_date": "2025-02-07",
      "last_synced_at": "2026-06-10T14:43:36.794Z",
      "location_count": 1,
      "location_summary": "Walnut Creek, California",
      "locations": [
        {
          "city": "Walnut Creek",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05357404"
    },
    {
      "nct_id": "NCT07116551",
      "title": "Early Feasibility Study (EFS) of Abbott's Balloon-expandable (BE) TAVI System for the Treatment of Severe, Symptomatic Aortic Stenosis",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Symptomatic Severe Aortic Stenosis"
      ],
      "interventions": [
        {
          "name": "Abbott BE TAVI System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 11,
      "start_date": "2025-10-30",
      "completion_date": "2031-06",
      "has_results": false,
      "last_update_posted_date": "2026-02-06",
      "last_synced_at": "2026-06-10T14:43:36.794Z",
      "location_count": 4,
      "location_summary": "Wichita, Kansas • Minneapolis, Minnesota • New York, New York + 1 more",
      "locations": [
        {
          "city": "Wichita",
          "state": "Kansas"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07116551"
    },
    {
      "nct_id": "NCT04056715",
      "title": "Extended ECG Monitoring in HCM Patients",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypertrophic Cardiomyopathy",
        "Nonsustained Ventricular Tachycardia",
        "Ventricular Tachycardia",
        "Atrial Fibrillation",
        "Arrhythmia"
      ],
      "interventions": [
        {
          "name": "Zio XT",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "iRhythm Technologies, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 250,
      "start_date": "2020-01-14",
      "completion_date": "2022-04-18",
      "has_results": false,
      "last_update_posted_date": "2023-03-01",
      "last_synced_at": "2026-06-10T14:43:36.794Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04056715"
    },
    {
      "nct_id": "NCT00598754",
      "title": "Diagnostic Three Dimensional Echocardiography Study Protocol",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Aortic Valve Stenosis",
        "Aortic Valve Insufficiency"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2001-06",
      "completion_date": "2008-07",
      "has_results": false,
      "last_update_posted_date": "2017-01-11",
      "last_synced_at": "2026-06-10T14:43:36.794Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00598754"
    },
    {
      "nct_id": "NCT03758651",
      "title": "Williams Syndrome Strength, Hormones, Activity & Adiposity, DNA Programming, Eating Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Williams Syndrome",
        "Lipedema"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 144,
      "start_date": "2018-10-01",
      "completion_date": "2023-09-14",
      "has_results": false,
      "last_update_posted_date": "2023-10-19",
      "last_synced_at": "2026-06-10T14:43:36.794Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03758651"
    },
    {
      "nct_id": "NCT03225001",
      "title": "PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - Nested Registry 3/Valve-in-Valve",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Stenosis",
        "Cardiomyopathy, Hypertrophic"
      ],
      "interventions": [
        {
          "name": "Edwards SAPIEN XT transcatheter valve, Model 9300TFX",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Edwards Lifesciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 197,
      "start_date": "2012-06-11",
      "completion_date": "2020-10-28",
      "has_results": true,
      "last_update_posted_date": "2021-03-09",
      "last_synced_at": "2026-06-10T14:43:36.794Z",
      "location_count": 46,
      "location_summary": "La Jolla, California • Los Angeles, California • Sacramento, California + 39 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03225001"
    },
    {
      "nct_id": "NCT02432092",
      "title": "Pediatric Cardiomyopathy Mutation Analysis",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiomyopathies",
        "Dilated Cardiomyopathy",
        "Hypertrophic Cardiomyopathy",
        "Restrictive Cardiomyopathy",
        "Arrhythmogenic Right Ventricular Cardiomyopathy",
        "Left Ventricular Non-compaction Cardiomyopathy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 300,
      "start_date": "2014-04",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-06-26",
      "last_synced_at": "2026-06-10T14:43:36.794Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02432092"
    }
  ]
}