{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Apnea+of+Prematurity&page=2",
    "query": {
      "condition": "Apnea of Prematurity",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Apnea+of+Prematurity&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T02:07:53.130Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01751724",
      "title": "Caffeine to Reduce Mechanical Ventilation in Preterm Infants",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prematurity",
        "Apnea",
        "Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Caffeine citrate",
          "type": "DRUG"
        },
        {
          "name": "Normal saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "5 Days",
        "sex": "ALL",
        "summary": "1 Day to 5 Days"
      },
      "enrollment_count": 87,
      "start_date": "2012-12",
      "completion_date": "2016-01",
      "has_results": true,
      "last_update_posted_date": "2017-06-19",
      "last_synced_at": "2026-06-11T02:07:53.130Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01751724"
    },
    {
      "nct_id": "NCT02293824",
      "title": "Effect of Feedings on Caffeine in Premature Infants",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Apnea of Prematurity",
        "Premature Newborn",
        "Caffeine"
      ],
      "interventions": [
        {
          "name": "Caffeine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "15 Days",
        "sex": "ALL",
        "summary": "Up to 15 Days"
      },
      "enrollment_count": 50,
      "start_date": "2014-12",
      "completion_date": "2017-06-30",
      "has_results": false,
      "last_update_posted_date": "2017-09-13",
      "last_synced_at": "2026-06-11T02:07:53.130Z",
      "location_count": 2,
      "location_summary": "Chapel Hill, North Carolina • Durham, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02293824"
    },
    {
      "nct_id": "NCT03414671",
      "title": "The Effect of Standardizing the Definition of a Clinically Significant Cardiopulmonary Event on Length of Stay",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Apnea of Prematurity"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Pediatrix",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "23 Weeks",
        "maximum_age": "29 Weeks",
        "sex": "ALL",
        "summary": "23 Weeks to 29 Weeks"
      },
      "enrollment_count": 160,
      "start_date": "2018-06-01",
      "completion_date": "2021-09-21",
      "has_results": false,
      "last_update_posted_date": "2021-10-04",
      "last_synced_at": "2026-06-11T02:07:53.130Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03414671"
    },
    {
      "nct_id": "NCT02524249",
      "title": "Early Versus Late Caffeine for ELBW Newborns",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bronchopulmonary Dysplasia",
        "Apnea of Prematurity"
      ],
      "interventions": [
        {
          "name": "Caffeine",
          "type": "DRUG"
        },
        {
          "name": "Placebo (dextrose)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wayne State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "4 Weeks",
        "sex": "ALL",
        "summary": "Up to 4 Weeks"
      },
      "enrollment_count": 110,
      "start_date": "2015-09",
      "completion_date": "2019-06",
      "has_results": false,
      "last_update_posted_date": "2022-05-02",
      "last_synced_at": "2026-06-11T02:07:53.130Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02524249"
    },
    {
      "nct_id": "NCT00296231",
      "title": "Nasal High Frequency Ventilation in Preterm Infants: A Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Infant Respiratory Distress Syndrome",
        "Respiratory Insufficiency",
        "Apnea of Prematurity"
      ],
      "interventions": [
        {
          "name": "Nasal high frequency ventilation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Tarah T Colaizy",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Days",
        "maximum_age": "3 Months",
        "sex": "ALL",
        "summary": "7 Days to 3 Months"
      },
      "enrollment_count": 14,
      "start_date": "2006-02",
      "completion_date": "2008-02",
      "has_results": true,
      "last_update_posted_date": "2018-02-09",
      "last_synced_at": "2026-06-11T02:07:53.130Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00296231"
    },
    {
      "nct_id": "NCT03695900",
      "title": "Arterial Oxygen Saturation on Ventilatory Stability in Extremely Premature Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Apnea of Prematurity",
        "Desaturation of Blood",
        "Central Apnea",
        "Periodic Breathing",
        "Obstructive Apnea of Newborn"
      ],
      "interventions": [
        {
          "name": "Targeting SpO2 at 93-95%",
          "type": "OTHER"
        },
        {
          "name": "Targeting SpO2 at 90-92%",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Weeks",
        "sex": "ALL",
        "summary": "Up to 18 Weeks"
      },
      "enrollment_count": 19,
      "start_date": "2018-11-01",
      "completion_date": "2019-11-08",
      "has_results": false,
      "last_update_posted_date": "2023-05-10",
      "last_synced_at": "2026-06-11T02:07:53.130Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03695900"
    },
    {
      "nct_id": "NCT03333161",
      "title": "Prematurity Related Ventilatory Control (PRE-VENT) - Specific Aim 2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infant,Premature"
      ],
      "interventions": [
        {
          "name": "Cardiorespiratory monitoring",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "15 Days",
        "sex": "ALL",
        "summary": "1 Day to 15 Days"
      },
      "enrollment_count": 25,
      "start_date": "2018-04-09",
      "completion_date": "2021-03-30",
      "has_results": false,
      "last_update_posted_date": "2021-09-21",
      "last_synced_at": "2026-06-11T02:07:53.130Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03333161"
    },
    {
      "nct_id": "NCT03340727",
      "title": "Moderately Preterm Infants With Caffeine at Home for Apnea (MoCHA) Trial",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Apnea of Prematurity"
      ],
      "interventions": [
        {
          "name": "Caffeine Citrate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "29 Weeks",
        "maximum_age": "33 Weeks",
        "sex": "ALL",
        "summary": "29 Weeks to 33 Weeks"
      },
      "enrollment_count": 827,
      "start_date": "2019-02-27",
      "completion_date": "2023-03-20",
      "has_results": true,
      "last_update_posted_date": "2024-07-31",
      "last_synced_at": "2026-06-11T02:07:53.130Z",
      "location_count": 16,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • Atlanta, Georgia + 12 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03340727"
    },
    {
      "nct_id": "NCT03670732",
      "title": "CPAP vs.Unsynchronized NIPPV at Equal Mean Airway Pressure",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prematurity",
        "Respiratory Distress Syndrome",
        "Apnea of Prematurity"
      ],
      "interventions": [
        {
          "name": "continuous positive airway pressure",
          "type": "OTHER"
        },
        {
          "name": "nasal intermittent positive pressure ventilation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Women and Infants Hospital of Rhode Island",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "Up to 6 Months"
      },
      "enrollment_count": 52,
      "start_date": "2017-09-30",
      "completion_date": "2020-06-30",
      "has_results": false,
      "last_update_posted_date": "2024-07-30",
      "last_synced_at": "2026-06-11T02:07:53.130Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03670732"
    },
    {
      "nct_id": "NCT07570121",
      "title": "Pharmacokinetics and Placental Transfer of Caffeine",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Preterm Labor With Preterm Delivery",
        "Premature Birth",
        "Apnea of Prematurity",
        "Respiratory Distress Syndrome",
        "Bronchopulmonary Dysplasia"
      ],
      "interventions": [
        {
          "name": "Caffeine citrate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2026-06-01",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-06-04",
      "last_synced_at": "2026-06-11T02:07:53.130Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07570121"
    }
  ]
}