{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arrested+Dental+Caries",
    "query": {
      "condition": "Arrested Dental Caries"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 14,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arrested+Dental+Caries&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:46:16.986Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04186663",
      "title": "Pharmacokinetics of Advantage Arrest in Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Silver Diamine Fluoride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Advantage Silver Dental Arrest, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "13 Years",
        "sex": "ALL",
        "summary": "3 Years to 13 Years"
      },
      "enrollment_count": 59,
      "start_date": "2019-08-01",
      "completion_date": "2020-03-31",
      "has_results": true,
      "last_update_posted_date": "2022-03-10",
      "last_synced_at": "2026-05-22T09:46:16.986Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04186663"
    },
    {
      "nct_id": "NCT04255251",
      "title": "Effectiveness Silver Diamine Fluoride Versus Sodium Fluoride in Arresting Caries Around Crown Margins in Older Adults",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Caries Roots",
        "Flouride Varnish",
        "Caries; Dentin",
        "Caries Arrested"
      ],
      "interventions": [
        {
          "name": "Silver Diammine Fluoride",
          "type": "DRUG"
        },
        {
          "name": "Fluoride Varnishes",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of New England",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "65 Years to 85 Years"
      },
      "enrollment_count": 200,
      "start_date": "2021-06-26",
      "completion_date": "2024-01-03",
      "has_results": false,
      "last_update_posted_date": "2021-10-05",
      "last_synced_at": "2026-05-22T09:46:16.986Z",
      "location_count": 1,
      "location_summary": "Portland, Maine",
      "locations": [
        {
          "city": "Portland",
          "state": "Maine"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04255251"
    },
    {
      "nct_id": "NCT03649659",
      "title": "Effectiveness of Silver Diamine Fluoride (SDF) in Arresting Cavitated Caries Lesions",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cavities of Teeth"
      ],
      "interventions": [
        {
          "name": "Silver Diamine Fluoride",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": "71 Months",
        "sex": "ALL",
        "summary": "12 Months to 71 Months"
      },
      "enrollment_count": 830,
      "start_date": "2018-10-08",
      "completion_date": "2023-04-27",
      "has_results": true,
      "last_update_posted_date": "2025-01-07",
      "last_synced_at": "2026-05-22T09:46:16.986Z",
      "location_count": 3,
      "location_summary": "Iowa City, Iowa • Ann Arbor, Michigan • New York, New York",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03649659"
    },
    {
      "nct_id": "NCT04933331",
      "title": "Early Caries Lesion Management Observational Study",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Initial Caries",
        "Arrested Dental Caries",
        "Cavitated Caries",
        "Dental Caries",
        "Dental Caries in Children"
      ],
      "interventions": [
        {
          "name": "Curodont Repair Fluoride Plus",
          "type": "DRUG"
        },
        {
          "name": "Silver Diamine Fluoride",
          "type": "DEVICE"
        },
        {
          "name": "Glass Ionomer Sealant",
          "type": "DEVICE"
        },
        {
          "name": "Fluoride varnish",
          "type": "DEVICE"
        },
        {
          "name": "Fluoride toothpaste",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "CareQuest Institute for Oral Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "4 Years and older"
      },
      "enrollment_count": 744,
      "start_date": "2020-12-07",
      "completion_date": "2024-03-31",
      "has_results": false,
      "last_update_posted_date": "2023-11-24",
      "last_synced_at": "2026-05-22T09:46:16.986Z",
      "location_count": 4,
      "location_summary": "Dothan, Alabama • Westborough, Massachusetts • Bend, Oregon + 1 more",
      "locations": [
        {
          "city": "Dothan",
          "state": "Alabama"
        },
        {
          "city": "Westborough",
          "state": "Massachusetts"
        },
        {
          "city": "Bend",
          "state": "Oregon"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04933331"
    },
    {
      "nct_id": "NCT05670743",
      "title": "Pharmacokinetics of Advantage Arrest in Healthy Children 13-Months to 13-Years of Age",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Dental Caries in Children"
      ],
      "interventions": [
        {
          "name": "38% silver diamine fluoride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Advantage Silver Dental Arrest, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Months",
        "maximum_age": "13 Years",
        "sex": "ALL",
        "summary": "13 Months to 13 Years"
      },
      "enrollment_count": 23,
      "start_date": "2023-03-01",
      "completion_date": "2024-08-01",
      "has_results": false,
      "last_update_posted_date": "2024-08-06",
      "last_synced_at": "2026-05-22T09:46:16.986Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05670743"
    },
    {
      "nct_id": "NCT07213661",
      "title": "LT Comparative Effectiveness of 2 Caries Treatments",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "A \"simple medical strategy\" consisting of silver diamine fluoride (SDF)",
          "type": "DEVICE"
        },
        {
          "name": "A \"typical dental strategy\" consisting of atraumatic restorative treatment (ART) with glass ionomer cement + Fluoride Varnish (FV)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Case Western Reserve University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "62 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "62 Years and older"
      },
      "enrollment_count": 480,
      "start_date": "2025-10-08",
      "completion_date": "2030-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-13",
      "last_synced_at": "2026-05-22T09:46:16.986Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07213661"
    },
    {
      "nct_id": "NCT02536040",
      "title": "Stopping Cavities Study: Diammine Silver Fluoride",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "38% diammine silver fluoride",
          "type": "DRUG"
        },
        {
          "name": "Water",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Advantage Dental Services, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "24 Months",
        "maximum_age": "60 Months",
        "sex": "ALL",
        "summary": "24 Months to 60 Months"
      },
      "enrollment_count": 66,
      "start_date": "2016-01",
      "completion_date": "2016-07",
      "has_results": true,
      "last_update_posted_date": "2020-01-23",
      "last_synced_at": "2026-05-22T09:46:16.986Z",
      "location_count": 1,
      "location_summary": "Redmond, Oregon",
      "locations": [
        {
          "city": "Redmond",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02536040"
    },
    {
      "nct_id": "NCT04538963",
      "title": "Arrest of Proximal Caries Using Orthodontic Bands and Glass Ionomer Cement",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries Class II",
        "Dental Caries in Children",
        "Dental Caries on Smooth Surface Limited to Enamel"
      ],
      "interventions": [
        {
          "name": "Orthodontic Band affixed with Glass Ionomer Cement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "209 Months",
        "sex": "ALL",
        "summary": "5 Years to 209 Months"
      },
      "enrollment_count": 38,
      "start_date": "2020-09-03",
      "completion_date": "2023-06",
      "has_results": false,
      "last_update_posted_date": "2021-09-05",
      "last_synced_at": "2026-05-22T09:46:16.986Z",
      "location_count": 2,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04538963"
    },
    {
      "nct_id": "NCT06890676",
      "title": "Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periodontitis",
        "Gingivitis",
        "Periodontal Disease",
        "Periodontal Infections",
        "Oral Infections",
        "Periapical Infections",
        "Pneumonia",
        "Diabetes"
      ],
      "interventions": [
        {
          "name": "Comprehensive Oral Evaluation",
          "type": "OTHER"
        },
        {
          "name": "Intraoral Complete Radiographic Series",
          "type": "OTHER"
        },
        {
          "name": "• Teledentistry-synchronous and asynchronous",
          "type": "OTHER"
        },
        {
          "name": "Periodontal Therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Periodontal Maintenance Procedure",
          "type": "PROCEDURE"
        },
        {
          "name": "Application of Caries Arresting Medicament",
          "type": "PROCEDURE"
        },
        {
          "name": "Oral Hygiene Assistance",
          "type": "OTHER"
        },
        {
          "name": "Referral for Treatment of Acute Oral Infection",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Missouri Department of Health and Senior Services",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "60 Years to 100 Years"
      },
      "enrollment_count": 150,
      "start_date": "2024-03-01",
      "completion_date": "2026-08-28",
      "has_results": false,
      "last_update_posted_date": "2025-03-26",
      "last_synced_at": "2026-05-22T09:46:16.986Z",
      "location_count": 1,
      "location_summary": "Jefferson City, Missouri",
      "locations": [
        {
          "city": "Jefferson City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06890676"
    },
    {
      "nct_id": "NCT03442309",
      "title": "Comparative Effectiveness of School-based Caries Prevention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries",
        "Quality of Life"
      ],
      "interventions": [
        {
          "name": "Silver Diamine Fluoride",
          "type": "DEVICE"
        },
        {
          "name": "Fluoride Varnishes",
          "type": "DEVICE"
        },
        {
          "name": "Glass Ionomer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "NYU College of Dentistry",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "5 Years to 12 Years"
      },
      "enrollment_count": 7418,
      "start_date": "2019-02-01",
      "completion_date": "2023-06-30",
      "has_results": true,
      "last_update_posted_date": "2025-02-26",
      "last_synced_at": "2026-05-22T09:46:16.986Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03442309"
    }
  ]
}